7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE
- CAS No.
- 99365-69-2
- Chemical Name:
- 7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE
- Synonyms
- 7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLINE HCL;1,2,3,4-tetrahydro-7-nitroisoquinoline hydrochloride;7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE;7-Nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride, 97+%;7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1);Isoquinoline,1,2,3,4-tetrahydro-7-nitro-, hydrochloride (1:1)
- CBNumber:
- CB1227282
- Molecular Formula:
- C9H11ClN2O2
- Molecular Weight:
- 214.65
- MDL Number:
- MFCD07371494
- MOL File:
- 99365-69-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 285403 | 1g | $382 |
| 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 285403 | 2g | $571 |
| 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 285403 | 5g | $947 |
| 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 285403 | 10g | $1426 |
| 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 285403 | 25g | $2575 |
| More product size | |||
| Melting point | 214-216 °C(Solv: methanol (67-56-1)) |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| Appearance | Light brown to gray Solid |
| CAS DataBase Reference | 99365-69-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| HS Code | 2933499090 | |||||||||
| NFPA 704 |
|
7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 285403 | 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 99365-69-2 | 1g | $382 | 2026-06-03 | Buy |
| Usbiological | 285403 | 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 99365-69-2 | 2g | $571 | 2026-06-03 | Buy |
| Usbiological | 285403 | 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 99365-69-2 | 5g | $947 | 2026-06-03 | Buy |
| Usbiological | 285403 | 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 99365-69-2 | 10g | $1426 | 2026-06-03 | Buy |
| Usbiological | 285403 | 7-Nitro-1,2,3,4-tetrahydroisoquinoline HCl Asreported | 99365-69-2 | 25g | $2575 | 2026-06-03 | Buy |
7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE Chemical Properties,Uses,Production
Synthesis
91-21-4
99365-69-2
7-Nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride was synthesized as follows: 1,2,3,4-tetrahydroisoquinoline (13.3 g, 0.1 mol) was dissolved in concentrated sulfuric acid (50 mL) and cooled to 0-5°C. At this temperature, potassium nitrate (11.12 g, 1.1 mol) was added in batches to ensure that the temperature of the reaction did not exceed 5°C. After addition, the reaction was allowed to proceed. After addition, the mixture was stirred at room temperature overnight. After completion of the reaction, the mixture was slowly poured into ice water. The pH was adjusted to alkaline with ammonium hydroxide solution and subsequently extracted with dichloromethane (CH2Cl2). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated to dryness under reduced pressure. The crude product was dissolved in ethanol (100 mL) and 2.8 M ethanol solution of hydrogen chloride (40 mL) was added. The precipitated solid was collected by filtration and recrystallized from methanol to give the white solid product 7-nitro-1,2,3,4-tetrahydroisoquinoline hydrochloride (10.30 g, 48% yield). The melting point of the product was 268-270°C. IR (KBr, cm-1): 2944, 2764, 1589, 1523, 1429, 1345, 1090. 1H NMR (300 MHz, DMSO-d6) δ ppm: 3.13 (t, J = 6.15 Hz, 2H), 3.35 (t, J = 6.22 Hz, 2H), 4.35 (s, 2H). 4.35 (s, 2H), 7.50 (d, J = 8.49 Hz, 1H), 8.08 (dd, J = 8.49, 2.49 Hz, 1H), 8.19 (d, J = 2.34 Hz, 1H), 9.96 (s, 2H).
References
[1] Patent: US2010/234340, 2010, A1. Location in patent: Page/Page column 21
[2] Patent: US2006/40978, 2006, A1. Location in patent: Page/Page column 9
[3] Chemistry - A European Journal, 2009, vol. 15, # 4, p. 885 - 900
[4] Patent: EP3363803, 2018, A1. Location in patent: Paragraph 0153
[5] Patent: EP3401315, 2018, A1. Location in patent: Paragraph 0148; 0149
7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Famo Biotech Co Ltd | +86-36680037 +86-18550473860 | mayan@famobiotech.com;sales@famobiotech.com | China | 528 | 58 |
View Lastest Price from 7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-02-02 | 7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE
99365-69-2
|
$3.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 7-NITRO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE HYDROCHLORIDE
99365-69-2
- $3.00
- 98%
- Career Henan Chemical Co
