ChemicalBook >> CAS DataBase List >>3,5-Dichloro-4-fluorobenzotrifluoride
3,5-Dichloro-4-fluorobenzotrifluoride
- CAS No.
- 77227-81-7
- Chemical Name:
- 3,5-Dichloro-4-fluorobenzotrifluoride
- Synonyms
- 1,3-DICHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZENE;3,5-Dichloro-4-fluoronitrobezene;3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE;3,5-dichloro-4- chlorobenzotrifluoride;3,5-Dichloro-4-fluorobenzotrifluoride98%;3,5-Dichloro-4-fluorobenzotrifluoride 98%;2,6-Dichloro-4-trifluoromethylfluorobenzene;Benzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)-;3,5-DICHLORO-ALPHA,ALPHA,ALPHA-4-TETRAFLUOROTOLUENE;3,5-dichloro-4-fluoro-alpha,alpha,alpha-trifluorotoluene
- CBNumber:
- CB1242849
- Molecular Formula:
- C7H2Cl2F4
- Molecular Weight:
- 232.99
- MDL Number:
- MFCD00068183
- MOL File:
- 77227-81-7.mol
- MSDS File:
- SDS
Last updated:2026-05-27 23:17:29
| Product description | Number | Pack Size | Price |
| 3,5-Dichloro-4-fluorobenzotrifluoride 98% | 416576 | 5g | $203 |
| 3,5-Dichloro-4-fluorobenzotrifluoride 98% | PC2403 | 1g | $62 |
| 3,5-Dichloro-4-fluorobenzotrifluoride 98% | PC2403 | 5g | $104 |
| 3,5-Dichloro-4-fluorobenzotrifluoride 98% | PC2403 | 25g | $313 |
| 3,5-Dichloro-4-fluorobenzotrifluoride 98% | PC2403 | 1g | $62 |
| More product size | |||
| Boiling point | 166-168 °C (lit.) |
|---|---|
| Density | 1.555 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 164 °F |
| storage temp. | Storage temp. 2-8°C |
| form | liquid |
| color | Clear |
| BRN | 6199573 |
| InChI | 1S/C7H2Cl2F4/c8-4-1-3(7(11,12)13)2-5(9)6(4)10/h1-2H |
| InChIKey | BWQFQKZDLBJZAW-UHFFFAOYSA-N |
| SMILES | Fc1c(Cl)cc(cc1Cl)C(F)(F)F |
| CAS DataBase Reference | 77227-81-7(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H318 | |||||||||
| Precautionary statements | P280-P301+P310+P330-P305+P351+P338+P310 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 2810 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29039990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications | Acute Tox. 3 Oral Eye Dam. 1 |
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| NFPA 704 |
|
3,5-Dichloro-4-fluorobenzotrifluoride price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 416576 | 3,5-Dichloro-4-fluorobenzotrifluoride 98% | 77227-81-7 | 5g | $203 | 2023-01-07 | Buy |
| Apolloscientific | PC2403 | 3,5-Dichloro-4-fluorobenzotrifluoride 98% | 77227-81-7 | 1g | $62 | 2026-06-04 | Buy |
| Apolloscientific | PC2403 | 3,5-Dichloro-4-fluorobenzotrifluoride 98% | 77227-81-7 | 5g | $104 | 2026-06-04 | Buy |
| Apolloscientific | PC2403 | 3,5-Dichloro-4-fluorobenzotrifluoride 98% | 77227-81-7 | 25g | $313 | 2026-06-04 | Buy |
| Apolloscientific | PC2403 | 3,5-Dichloro-4-fluorobenzotrifluoride 98% | 77227-81-7 | 1g | $62 | 2026-06-04 | Buy |
3,5-Dichloro-4-fluorobenzotrifluoride Chemical Properties,Uses,Production
Chemical Properties
CLEAR LIGHT YELLOW LIQUID
Uses
3,5-Dichloro-4-fluorobenzotrifluoride may be used for the synthesis of 3-[4-[1-(2,6-dichloro-3-iodo-4-trifluoromethylphenyl)-5-iodopyrazolo]]-3-(trifluoromethyl)diazirine.
General Description
3,5-Dichloro-4-fluorobenzotrifluoride is an aryl fluorinated building block.
Synthesis
In a 1L three-necked reaction flask equipped with a stirrer, reflux condenser and temperature ground, 200 g of 3,4,5-trichlorobenzotrifluoride and 200 g of potassium fluoride and 500 ml of cyclobutanesulfone were added, then heated to 190C, kept warm and stirred for 20 hours and then cooled down to 100C. 200 g of the crude product (containing about 10% of the cyclobutanesulfone) was evaporated under 0.01 MPa pressure. Then the temperature was raised to 150 and the pressure was reduced to recover the cyclobutanesulfone (can be directly used in the next batch of reaction). 200 g of crude 3,5-dichloro-4-fluorobenzotrifluoride was directly used in the next step of the ammoniation reaction.
3,5-Dichloro-4-fluorobenzotrifluoride Preparation Products And Raw materials
Global( 135)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3967 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 3,5-Dichloro-4-fluorobenzotrifluoride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 3,5-Dichloro-4-fluorobenzotrifluoride
77227-81-7
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2026-02-02 | 3,5-Dichloro-4-fluorobenzotrifluoride
77227-81-7
|
50mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2021-08-12 | 3,5-Dichloro-4-fluorobenzotrifluoride
77227-81-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 3,5-Dichloro-4-fluorobenzotrifluoride
77227-81-7
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3,5-Dichloro-4-fluorobenzotrifluoride
77227-81-7
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- 3,5-Dichloro-4-fluorobenzotrifluoride
77227-81-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
77227-81-7(3,5-Dichloro-4-fluorobenzotrifluoride )Related Search:
3,5-DICHLORO-ALPHA,ALPHA,ALPHA-4-TETRAFLUOROTOLUENE
3,5-dichloro-4-fluoro-alpha,alpha,alpha-trifluorotoluene
3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE
3,5-Dichloro-4-fluoronitrobezene
3,5-dichloro-4- chlorobenzotrifluoride
Benzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)-
3,5-Dichloro-4-fluorobenzotrifluoride 98%
3,5-Dichloro-4-fluorobenzotrifluoride98%
3,5-Dichloro-alpha,alpha,alpha,4-tetrafluorotoluene, 1,3-Dichloro-2-fluoro-5-(trifluoromethyl)benzene
1,3-DICHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)BENZENE
2,6-Dichloro-4-trifluoromethylfluorobenzene
1,3-Dichloro-2-fluoro-5-(trifluoromethyl)benzene - [D94405]
77227-81-7
Cl2C6H2FCF3
C7H2Cl2F4
Aryl
C7
Building Blocks
Halogenated Hydrocarbons
Organic Building Blocks
Aryl
C7
Halogenated Hydrocarbons
Aryl Fluorinated Building Blocks
Building Blocks
Chemical Synthesis
Fluorinated Building Blocks
Halogenated Hydrocarbons
Organic Building Blocks
Organic Fluorinated Building Blocks
Other Fluorinated Organic Building Blocks
