(5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER
- CAS No.
- 227939-01-7
- Chemical Name:
- (5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER
- Synonyms
- tert-Butyl (5-bromopyridin-2-yl);N-Boc-N-methyl-5-bromo-2-pyridinamine;2-(N-BOC-N-methylamino)-5-bromopyridine;ert-butylN-(5-bromopyridin-2-yl)-N-methylcarbamate;(5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER;Carbamic acid, (5-bromo-2-pyridinyl)methyl-, 1,1-dimethylethyl ester;Carbamic acid, N-(5-bromo-2-pyridinyl)-N-methyl-, 1,1-dimethylethyl ester;(5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER ISO 9001：2015 REACH
- CBNumber:
- CB12459157
- Molecular Formula:
- C11H15BrN2O2
- Molecular Weight:
- 287.15
- MDL Number:
- MFCD12546613
- MOL File:
- 227939-01-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate | 300819 | 250.00mg | $25 |
| tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate | 300819 | 1.00g | $84 |
| tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate | 300819 | 5.00g | $235 |
| (5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester | 073005 | 1.00g | $77 |
| (5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester | 073005 | 5.00g | $234 |
(5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 300819 | tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate | 227939-01-7 | 250.00mg | $25 | 2026-05-19 | Buy |
| Matrix Scientific | 300819 | tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate | 227939-01-7 | 1.00g | $84 | 2026-05-19 | Buy |
| Matrix Scientific | 300819 | tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate | 227939-01-7 | 5.00g | $235 | 2026-05-19 | Buy |
| Matrix Scientific | 073005 | (5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester | 227939-01-7 | 1.00g | $77 | 2026-05-18 | Buy |
| Matrix Scientific | 073005 | (5-Bromopyridin-2-yl)methyl-carbamic acidtert-butyl ester | 227939-01-7 | 5.00g | $234 | 2026-05-18 | Buy |
(5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER Chemical Properties,Uses,Production
Synthesis
84539-30-0
24424-99-5
227939-01-7
General procedure: 5-bromo-2-(methylamino)pyridine (2.0 g, 10.7 mmol) and di-tert-butyl dicarbonate (2.8 g, 12.8 mmol, 3.0 mL) were dissolved in tetrahydrofuran (20 mL) under nitrogen protection and cooled to 0 °C. NaHMDS (1 M, 12 mL) was added slowly, keeping the reaction temperature at 0 °C. After addition, the reaction mixture was gradually warmed to 20 °C and stirred continuously for 13 hours. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent: petroleum ether/ethyl acetate = 3/1) and a small amount of raw material residue and a new point of lower polarity (product point) were observed. Upon completion of the reaction, the reaction was quenched with saturated sodium bicarbonate solution (30 mL) and extracted with ethyl acetate (50 mL × 2). The organic phases were combined, washed with saturated saline (30 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate = 10/1~3/1) to afford 5-bromo-2-(N-methyl-N-(tert-butoxycarbonyl)amino)pyridine (2.8 g, 91% yield) as a light yellow liquid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) and ESI-MS: 1H NMR δ 8.40-8.39 (m, 1H), 7.71-7.65 (m, 2H), 3.37 (s, 3H), 1.49 (s, 9H); ESI-MS (m/z): 287.0 ([M+H]+).
References
[1] Patent: WO2017/120429, 2017, A1. Location in patent: Page/Page column 261
[2] Patent: WO2007/86800, 2007, A1. Location in patent: Page/Page column 94
[3] Patent: CN104292242, 2017, B. Location in patent: Paragraph 0105; 0115
(5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
(5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23506 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52906 | 58 | |
| ANHUI BYERSEN BIOTECH CO. LTD | +86-15385096007 +86-17755058861 | amy@byersenchemical.com | China | 10000 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| BeiJing Hwrk Chemicals Limted | 0757-86329057 18934348241 | sales4.gd@hwrkchemical.com | China | 14060 | 55 |
| Energy Chemical | 021-021-58432009 400-005-6266 | sales8178@energy-chemical.com | China | 44848 | 61 |
| Shanghai Litong Chemical Technology Co.,Ltd. | 13598610367 0373-7129549 | 2468833170@qq.com | China | 932 | 58 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
View Lastest Price from (5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | (5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER
227939-01-7
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-05-13 | 2-(N-BOC-N-MethylaMino)-5-broMopyridine
227939-01-7
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
-
- (5-BROMOPYRIDIN-2-YL)METHYL-CARBAMIC ACID TERT-BUTYL ESTER
227939-01-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-(N-BOC-N-MethylaMino)-5-broMopyridine
227939-01-7
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
