2-Amino-6-bromothiazolo[5,4-b]pyridine
- CAS No.
- 1160791-13-8
- Chemical Name:
- 2-Amino-6-bromothiazolo[5,4-b]pyridine
- Synonyms
- 2-Amino-6-bromothiazolo[5,4-b]pyridine;Thiazolo[5,4-b]pyridin-2-amine, 6-bromo-;6-BroMo-thiazolo[5,4-b]pyridin-2-ylaMine;6-bromo-[1,3]thiazolo[5,4-b]pyridin-2-amine
- CBNumber:
- CB12489646
- Molecular Formula:
- C6H4BrN3S
- Molecular Weight:
- 230.09
- MDL Number:
- MFCD11846628
- MOL File:
- 1160791-13-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | A42152 | 100mg | $23 |
| 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | A42152 | 250mg | $28 |
| 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | A42152 | 1g | $80 |
| 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | A42152 | 5g | $370 |
| 6-bromothiazolo[5,4-b]pyridin-2-amine 95% | T96114 | 5G | $410 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
2-Amino-6-bromothiazolo[5,4-b]pyridine price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | A42152 | 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | 1160791-13-8 | 100mg | $23 | 2026-05-06 | Buy |
| Synthonix | A42152 | 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | 1160791-13-8 | 250mg | $28 | 2026-05-06 | Buy |
| Synthonix | A42152 | 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | 1160791-13-8 | 1g | $80 | 2026-05-06 | Buy |
| Synthonix | A42152 | 2-Amino-6-bromothiazolo[5,4-b]pyridine 97% | 1160791-13-8 | 5g | $370 | 2026-05-06 | Buy |
| ACHEMBLOCK | T96114 | 6-bromothiazolo[5,4-b]pyridin-2-amine 95% | 1160791-13-8 | 5G | $410 | 2026-05-27 | Buy |
2-Amino-6-bromothiazolo[5,4-b]pyridine Chemical Properties,Uses,Production
Uses
2-Amino-6-bromothiazo[5,4-B]pyridine is an organic intermediate that can be prepared in one step from 5-bromo-2-chloropyridine-3-amine and potassium thiocyanate, or in three steps from 3-amino-5-bromo-2-fluoropyridine and benzoyl isothiocyanate.
Synthesis
588730-01-2
1160791-13-8
General procedure for the synthesis of 2-amino-6-bromothiazolo[5,4-b]pyridin-2-yl from N-(6-bromothiazolo[5,4-b]pyridin-2-yl)benzamide: Dissolve N-(6-bromothiazolo[5,4-b]pyridin-2-yl)benzamide (2.0 g, 5.98 mmol) in 70% sulfuric acid (10.0 mL) and react by heating to 140 °C for 1 hour. Upon completion of the reaction (monitored by TLC), the reaction mixture was poured into crushed ice and the pH was adjusted to 8.0 with 30% aqueous sodium hydroxide, followed by extraction with ethyl acetate (3 x 150 mL). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford the target product 2-amino-6-bromothiazolo[5,4-b]pyridine (1.34 g, 98% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 7.85 (d, J=2.0 Hz, 1H), 8.05 (br s, 2H), 8.18 (d, J=2.0 Hz, 1H).
References
[1] Patent: WO2009/74812, 2009, A1. Location in patent: Page/Page column 91; 92
2-Amino-6-bromothiazolo[5,4-b]pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +86-18327326525 | masar@topule.com | China | 8467 | 58 |
| Young Lively PharminBlock Co.,Ltd | 18600731423 | jason_gao@yl-pharminblock.com | China | 1944 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Qingdao Dexin Chemical Co., Ltd | +86-15553333686 | 15553333686@qq.com | China | 3113 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10186 | 62 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8666 | 57 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3979 | 55 |





