ChemicalBook >> CAS DataBase List >>((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
![((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Structure](CAS/20150408/GIF/1103738-19-7.gif)
- CAS No.
- 1103738-19-7
- Chemical Name:
- ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
- Synonyms
- (3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone;SOTA-005;EOS-61383;LX-4211 int;6aS)-6-hydroxy-2;LX-4211 inermediate;LX-4211 intermediate;2-dimethyltetrahydrofuro[2;D-xylo-Pentodialdo-5,2-furanose;3]dioxol-5-yl)(morpholino)methanone
- CBNumber:
- CB12668005
- Molecular Formula:
- C12H19NO6
- Molecular Weight:
- 273.28
- MDL Number:
- MFCD25977365
- MOL File:
- 1103738-19-7.mol
- MSDS File:
- SDS
Last updated:2026-05-27 23:20:23
| Product description | Number | Pack Size | Price |
| ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | H16576 | 100mg | $15 |
| ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | H16576 | 250mg | $20 |
| ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | H16576 | 1g | $56 |
| ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | H16576 | 5g | $60 |
| ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | H16576 | 25g | $290 |
| More product size | |||
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Properties
| Boiling point | 479.3±45.0 °C(Predicted) |
|---|---|
| Density | 1.318±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| pka | 12.78±0.60(Predicted) |
| Appearance | Off-white to yellow Solid |
| InChI | InChI=1S/C12H19NO6/c1-12(2)18-9-7(14)8(17-11(9)19-12)10(15)13-3-5-16-6-4-13/h7-9,11,14H,3-6H2,1-2H3/t7-,8-,9+,11+/m1/s1 |
| InChIKey | ZHDDJWFZDNKWIC-REIXXSIJSA-N |
| SMILES | O=C(N1CCOCC1)[C@H]1[C@H]([C@H]2[C@@]([H])(O1)OC(O2)(C)C)O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | H16576 | ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | 1103738-19-7 | 100mg | $15 | 2026-05-06 | Buy |
| Synthonix | H16576 | ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | 1103738-19-7 | 250mg | $20 | 2026-05-06 | Buy |
| Synthonix | H16576 | ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | 1103738-19-7 | 1g | $56 | 2026-05-06 | Buy |
| Synthonix | H16576 | ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | 1103738-19-7 | 5g | $60 | 2026-05-06 | Buy |
| Synthonix | H16576 | ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 97% | 1103738-19-7 | 25g | $290 | 2026-05-06 | Buy |
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Chemical Properties,Uses,Production
Synthesis
To a solution of (3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid (5.0 g, 24.5 mmol) in THF (100 ML, 20.x.) was added TBTU (11.8 g, 1.5 equiv), N-methylmorpholine (NMM, 4.1 mL, 1.5 equiv) and the mixture was stirred at 20° C. for 30 min. Morpholine (3.2 mL, 1.5 equiv) was added, and the reaction mixture was stirred at 20° C. for an additional 6h. The solid was filtered off by filtration, and the cake was washed with THF (10 mL, 2.x. .x.2). The organic solution was concentrated under a vacuum. The residue was purified by silica gel column chromatography (hexanes: EtOAc, from 1:4 to 4: 1) to afford 4.3 g of the desired morpholine amide (((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone) as a white solid.
References
[1] Patent: US2009/30198, 2009, A1. Location in patent: Page/Page column 8
[2] Patent: US2010/16422, 2010, A1. Location in patent: Page/Page column 4
[3] Patent: EP2332947, 2011, A1. Location in patent: Page/Page column 6-7
[4] Patent: EP2661256, 2018, B1. Location in patent: Paragraph 0091
[5] Patent: CN106892948, 2017, A. Location in patent: Paragraph 0195; 0196; 0197; 0198
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Preparation Products And Raw materials
Global( 164)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai 3S Technology Co., Ltd | +86-18221206281 +86-18221206281 | luqing@3s-tech.net | China | 59 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1006 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32468 | 58 |
View Lastest Price from ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | LX-4211 intermediate
1103738-19-7
|
$31.00-81.00 | 99.88% | 10g | TargetMol Chemicals Inc. | ||
![(3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone pictures](/ProductImageEN/2023-06/Small/17c65710-2cd3-4f6c-ab02-9e98a8ae7fa4.png) |
2026-01-04 | (3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone
1103738-19-7
|
1kg | 99% | 200kg | Hangzhou ICH Biofarm Co., Ltd | ||
![(3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone pictures](/ProductImageEN/2023-06/Small/7fcc8821-37cf-42b6-a724-ceaa5a4e65d6.png) |
2026-01-04 | (3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone
1103738-19-7
|
1kg | 99% | 200kg | Hangzhou ICH Biofarm Co., Ltd |
-
- LX-4211 intermediate
1103738-19-7
- $31.00-81.00
- 99.88%
- TargetMol Chemicals Inc.
-
- (3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone
1103738-19-7
- $0.00
- 99%
- Hangzhou ICH Biofarm Co., Ltd
-
- (3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone
1103738-19-7
- $0.00
- 99%
- Hangzhou ICH Biofarm Co., Ltd
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Spectrum
1103738-19-7(((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone)Related Search:
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(3aR,5R,6S,6aR)-2,2-dimethyl-5-[(morpholin-4-yl)methyl]-tetrahydro-2H-furo[2,3-d][1,3]dioxol-6-ol
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SOTA-005
((3aS,5S,6R,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
LX-4211 intermediate
[(3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]-morpholin-4-ylmethanone
2-dimethyltetrahydrofuro[2
3]dioxol-5-yl)(morpholino)methanone
6aS)-6-hydroxy-2
((3aS,5R,6S,6aS)-6-hydroxy-2,2-diMethyltetrahydrofuro[2,3-d]...
D-xylo-Pentodialdo-5,2-furanose
(5S)-4,5-o-(1-Methylethylidene)-1-C-morpholin-4-yl-D-xylo-pentodialdo-5,2-furanose
(5S)-4,5-0-(1-Methylethylidene)-1-C-4- morpholinyl-D-xylo-pentodialdo-5,2-furanose
LX-4211 intermediate, 10 mM in DMSO
((3aS,5R,6S,6aS)-6-Hydroxy-2,2-dimethyl-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholin-4-yl)methanone
(3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone
1103738-19-7
