Motolimod
- CAS No.
- 172377-52-5
- Chemical Name:
- Motolimod
- Synonyms
- Estradiol Sulfamate;J-995;E2MATE;ES-J 995;PGL-2001;ZK-190628;BLE 00084;Estradiol 3-sulfamate;E2MATE|||BLE 00084|||ES-J 995;Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-sulfamate
- CBNumber:
- CB13159933
- Molecular Formula:
- C18H25NO4S
- Molecular Weight:
- 351.46
- MDL Number:
- MFCD00947822
- MOL File:
- 172377-52-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Estradiol 3-sulfamate | XGA37752 | 5mg | $1120.7 |
| Estradiol 3-sulfamate | XGA37752 | 10mg | $1559.1 |
| Estradiol 3-sulfamate | XGA37752 | 25mg | $2923.5 |
| Estradiol 3-sulfamate | XGA37752 | 50mg | $4677.5 |
| Estradiol 3-sulfamate 99.87% | CS-7149 | 5mg | $390 |
| Melting point | 202-204 °C(Solv: methanol (67-56-1)) |
|---|---|
| Boiling point | 531.1±60.0 °C(Predicted) |
| Density | 1.319±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 62.5 mg/mL (177.83 mM) |
| pka | 8.88±0.70(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | WO55ODW08Z |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360-H351 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
Motolimod price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XGA37752 | Estradiol 3-sulfamate | 172377-52-5 | 5mg | $1120.7 | 2026-06-05 | Buy |
| Biosynth | XGA37752 | Estradiol 3-sulfamate | 172377-52-5 | 10mg | $1559.1 | 2026-06-05 | Buy |
| Biosynth | XGA37752 | Estradiol 3-sulfamate | 172377-52-5 | 25mg | $2923.5 | 2026-06-05 | Buy |
| Biosynth | XGA37752 | Estradiol 3-sulfamate | 172377-52-5 | 50mg | $4677.5 | 2026-06-05 | Buy |
| ChemScene | CS-7149 | Estradiol 3-sulfamate 99.87% | 172377-52-5 | 5mg | $390 | 2026-06-04 | Buy |
Motolimod Chemical Properties,Uses,Production
Uses
Estradiol 3-sulfamate (BLE 00084; E2MATE; ES-J 995) is a potent, long-acting, and orally active steroid sulfatase inhibitor; inhibits estrone sulfatase with an IC50 of 251 nM and a Ki of 133 nM.
in vivo
Estradiol 3-sulfamate is readily transformed and absorbed in the gut into its oxidative metabolite, EMATE, and both compounds have already been shown to be potent, long-acting, and orally active STS inhibitors[2].
References
[1] Numazawa M, et al. Inhibition of estrone sulfatase by aromatase inhibitor-based estrogen 3-sulfamates. Steroids. 2006 May;71(5):371-9. DOI:10.1016/j.steroids.2005.12.004
[2] Pohl O, et al. Synergistic effects of E2MATE and norethindrone acetate on steroid sulfatase inhibition: a randomized phase I proof-of-principle clinical study in women of reproductive age. Reprod Sci. 2014 Oct;21(10):1256-65. DOI:10.1177/1933719114522526
Motolimod Preparation Products And Raw materials
Raw materials
Preparation Products
Motolimod Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39039 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16111 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-025-85560043 17301488900 | info@synzest.com | China | 9286 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 18351873721 | helen.zhang@synzest.com | China | 8295 | 58 |
View Lastest Price from Motolimod manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-25 | Estradiol 3-sulfamate
172377-52-5
|
$76.00-286.00 | 99.63% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-25 | Estradiol 3-sulfamate
172377-52-5
|
$76.00-286.00 | 99.63% | 10g | TargetMol Chemicals Inc. |
-
- Estradiol 3-sulfamate
172377-52-5
- $76.00-286.00
- 99.63%
- TargetMol Chemicals Inc.
-
- Estradiol 3-sulfamate
172377-52-5
- $76.00-286.00
- 99.63%
- TargetMol Chemicals Inc.
