Etelcalcetide HCl
- CAS No.
- 1334237-71-6
- Chemical Name:
- Etelcalcetide HCl
- Synonyms
- Etelcalcetide Hydrochloride;Parsabiv;velcalcetide hydrochloride;AMG416;AMG 416;KAI-4169;Etelcalcetide HCl;AMG 416 hydrochloride;KAI-4169 hydrochloride;Vicosidine hydrochloride
- CBNumber:
- CB13339874
- Molecular Formula:
- C38H74ClN21O10S2
- Molecular Weight:
- 1084.71186
- MDL Number:
- MFCD32004547
- MOL File:
- 1334237-71-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Etelcalcetide (hydrochloride) ≥95% | 26901 | 1mg | $41 |
| Etelcalcetide (hydrochloride) ≥95% | 26901 | 5mg | $186 |
| Etelcalcetide (hydrochloride) ≥95% | 26901 | 10mg | $351 |
| Etelcalcetide (hydrochloride) | 26901 | 1mg | $37 |
| Etelcalcetide (hydrochloride) | 26901 | 10mg | $319 |
| storage temp. | Store at -20°C |
|---|---|
| solubility |
DMSO:10.0(Max Conc. mg/mL);8.37(Max Conc. mM) PBS (pH 7.2):10.0(Max Conc. mg/mL);8.37(Max Conc. mM) Water:50.0(Max Conc. mg/mL);41.87(Max Conc. mM) |
| form | A crystalline solid |
| color | White to off-white |
| Sequence | Ac-d-Cys（Cys）-d-Ala-d-Arg-d-Arg-d-Arg-d-Ala-d-Arg-NH2 (Disulfide bridge: Cys-Cys) |
| InChIKey | CRSDUYHPKJMYMG-KZTORMJDNA-N |
| FDA UNII | 72PT5993DU |
| NCI Drug Dictionary | Parsabiv |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
Etelcalcetide HCl price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26901 | Etelcalcetide (hydrochloride) ≥95% | 1334237-71-6 | 1mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 26901 | Etelcalcetide (hydrochloride) ≥95% | 1334237-71-6 | 5mg | $186 | 2026-04-30 | Buy |
| Cayman Chemical | 26901 | Etelcalcetide (hydrochloride) ≥95% | 1334237-71-6 | 10mg | $351 | 2026-04-30 | Buy |
| Cayman Chemical | 26901 | Etelcalcetide (hydrochloride) | 1334237-71-6 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 26901 | Etelcalcetide (hydrochloride) | 1334237-71-6 | 10mg | $319 | 2024-03-01 | Buy |
Etelcalcetide HCl Chemical Properties,Uses,Production
Uses
Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease[1][2].
in vivo
Etelcalcetide hydrochloride (2.5 μg/h and 20 μg/h, infusion, 3 days) significantly reduces plasma PTH concentrations and decreased the renal expression of Cyp24a1 with a higher delivery rate[1].
| Animal Model: | C57BL7/6J male mice |
| Dosage: | 2.5 μg/h and 20 μg/h |
| Administration: | infusion, 3 days |
| Result: | Significantly reduced plasma PTH concentrations and unaltered Cldn14 expression with 2.5 μg/h, but decreased the renal expression of Cyp24a1 with 20 μg/h [1] |
References
[1] Differential parathyroid and kidney Ca2+-sensing receptor activation in autosomal dominant hypocalcemia 1 DOI:10.1016/j.ebiom.2022.103947
[2] Fujioka A, et al. Effect of etelcalcetide on parathyroid hormone secretion by primary hyperparathyroidism patient-derived primary parathyroid cells[J]. J Bone Miner Metab. 2021 May;39(3):396-403. DOI:10.1007/s00774-020-01158-2
Etelcalcetide HCl Preparation Products And Raw materials
Raw materials
Preparation Products
Etelcalcetide HCl Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan JiyunZen Tech Co., Ltd. | +86-18062099985 | Amyjiyunzen@yeah.net | China | 672 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11680 | 58 |
View Lastest Price from Etelcalcetide HCl manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-16 | Etelcalcetide hydrochloride
1334237-71-6
|
$30.00-105.00 | 100.00% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-06-08 | Etelcalcetide HCl | 1kg | 99% | 1 | Jinan Ruitong Biotech Co., Ltd. | ||
 |
2026-04-10 | Etelcalcetide Hydrochloride
1334237-71-6
|
$2.00-5.00 | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. |
-
- Etelcalcetide hydrochloride
1334237-71-6
- $30.00-105.00
- 100.00%
- TargetMol Chemicals Inc.
-
- Etelcalcetide HCl
- 99%
- Jinan Ruitong Biotech Co., Ltd.
-
- Etelcalcetide Hydrochloride
1334237-71-6
- $2.00-5.00
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
