FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-25
- CAS No.
- 107978-77-8
- Chemical Name:
- FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-25
- Synonyms
- CS1 peptide;Fibronectin connecting segment 1;FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-;FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-25;Fibronectin Type III Connecting Segment Fragment 1-25 >=90% (HPLC);L-Threonine, L-α-aspartyl-L-α-glutamyl-L-leucyl-L-prolyl-L-glutaminyl-L-leucyl-L-valyl-L-threonyl-L-leucyl-L-prolyl-L-histidyl-L-prolyl-L-asparaginyl-L-leucyl-L-histidylglycyl-L-prolyl-L-α-glutamyl-L-isoleucyl-L-leucyl-L-α-aspartyl-L-valyl-L-prolyl-L-seryl-;L-Threonine, L-alpha-aspartyl-L-alpha-glutamyl-L-leucyl-L-prolyl-L-glutaminyl-L-leucyl-L-valyl-L-threonyl-L-leucyl-L-prolyl-L-histidyl-L-prolyl-L-asparaginyl-L-leucyl-L-histidylglycyl-L-prolyl-L-alpha-glutamyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-valyl-L-prolyl-L-seryl-
- CBNumber:
- CB1401363
- Molecular Formula:
- C123H195N31O39
- Molecular Weight:
- 2732.05
- MDL Number:
- MFCD00214575
- MOL File:
- 107978-77-8.mol
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Fibronectin Type III Connecting Segment Fragment 1-25 ≥90% (HPLC) | F5007 | 1mg | $683 |
| Fibronectin Type III Connecting Segment Fragment 1-25 | CS-0142414 | 1mg | $1617 |
| Fibronectin Type III Connecting Segment Fragment 1-25 | CS-0142414 | 1mg | $1617 |
| Fibronectin Type III Connecting Segment Fragment 1-25 ≥95% | AA008ROW | 1mg | $267 |
| Fibronectin Type III Connecting Segment Fragment 1-25 ≥95% | AA008ROW | 5mg | $645 |
| Boiling point | 2583.2±65.0 °C(Predicted) |
|---|---|
| Density | 1.338±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| form | powder |
| biological source | synthetic (organic) |
| Sequence | Asp-Glu-Leu-Pro-Gln-Leu-Val-Thr-Leu-Pro-His-Pro-Asn-Leu-His-Gly-Pro-Glu-Ile-Leu-Asp-Val-Pro-Ser-Thr |
| InChIKey | NXAKDBCNODQXBZ-YSZCVPRFSA-N |
| UNSPSC Code | 12352202 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-25 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F5007 | Fibronectin Type III Connecting Segment Fragment 1-25 ≥90% (HPLC) | 107978-77-8 | 1mg | $683 | 2026-04-30 | Buy |
| ChemScene | CS-0142414 | Fibronectin Type III Connecting Segment Fragment 1-25 | 107978-77-8 | 1mg | $1617 | 2026-06-04 | Buy |
| ChemScene | CS-0142414 | Fibronectin Type III Connecting Segment Fragment 1-25 | 107978-77-8 | 1mg | $1617 | 2026-06-04 | Buy |
| aablocks | AA008ROW | Fibronectin Type III Connecting Segment Fragment 1-25 ≥95% | 107978-77-8 | 1mg | $267 | 2026-05-28 | Buy |
| aablocks | AA008ROW | Fibronectin Type III Connecting Segment Fragment 1-25 ≥95% | 107978-77-8 | 5mg | $645 | 2026-05-28 | Buy |
FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-25 Chemical Properties,Uses,Production
Uses
Fibronectin Type III Connecting Segment Fragment 1-25 is a peptide that is responsible for melanoma cell adhesion, and plays an important role in development of the peripheral nervous system in chicken[1][2].
Biological Activity
Fibronectin Type III Connecting Segment (IIICS) is responsible for melanoma cell adhesion. It is the predominant binding site of integrin α4β1, which is mediated through the aspartic acid residue present at position 21. Studies in chicken show th at alternative splicing in this region during development of the peripheral nervous system, is essential for the control cell-cell adhesion.
References
[1] A Komoriya, et al. The minimal essential sequence for a major cell type-specific adhesion site (CS1) within the alternatively spliced type III connecting segment domain of fibronectin is leucine-aspartic acid-valine. J Biol Chem. 1991 Aug 15;266(23):15075-9. PMID:1869542
[2] M J Humphries, et al. Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment. J Cell Biol. 1988 Apr;106(4):1289-97. DOI:10.1083/jcb.106.4.1289
FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-25 Preparation Products And Raw materials
Raw materials
Preparation Products
FIBRONECTIN TYPE III CONNECTING SEGMENT FRAGMENT 1-25 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEON (NANJING) BIOTECHNOLOGY CO., LTD. | +8615051830413 | sales.njleonbiotech@gmail.com | China | 5482 | 58 |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19103 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44909 | 58 |
| Hangzhou Beiputai Biopharmaceutical Co., Ltd | 0571-85350119 15888826472 | bptsales@163.com | China | 3833 | 58 |
| Merck KGaA | -- | ordercn@merckgroup.com | China | 6394 | 58 |
| Adooq Bioscience LLC | -- | sales@adooq.cn | China | 6215 | 58 |
| Cohesion Biosciences | -- | sales@cohesionbio.com | China | 6282 | 58 |
| Fuan Bio | 15002819872 | 2845971812@qq.com | China | 2103 | 58 |
