2,4-DIETHYLPYRIDINE DICARBOXYLATE
- CAS No.
- 41438-38-4
- Chemical Name:
- 2,4-DIETHYLPYRIDINE DICARBOXYLATE
- Synonyms
- diethyl pyridine-2,4-dicarboxylate;2,4-pyridine dicarboxylate;2,4-DPD;Ai3-17897;Diethyl-2,4-pdc;2,4-Pdc diethyl ester;2,4-Pyridinedicarboxylic;DIETHYL 2,4-PYRIDINECARBOXYLATE;2,4-DIETHYLPYRIDINE DICARBOXYLATE;Diethyl 2,4-pyridinedicarboxylate
- CBNumber:
- CB1454066
- Molecular Formula:
- C11H13NO4
- Molecular Weight:
- 223.23
- MDL Number:
- MFCD00152168
- MOL File:
- 41438-38-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) | D5518 | 200mg | $45 |
| Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) | D5518 | 1g | $135 |
| 2,4-DPD ≥98% | 71200 | 10mg | $21 |
| 2,4-DPD ≥98% | 71200 | 25mg | $46 |
| 2,4-DPD ≥98% | 71200 | 50mg | $86 |
| More product size | |||
| Melting point | 31 °C |
|---|---|
| Boiling point | 330.9±22.0 °C(Predicted) |
| Density | 1.165±0.06 g/cm3(Predicted) |
| vapor pressure | 0.022Pa at 25℃ |
| storage temp. | 2-8°C |
| solubility | ≤50mg/ml in ethanol;20mg/ml in DMSO;30mg/ml in dimethyl formamide |
| pka | -0.69±0.10(Predicted) |
| form | Crystalline |
| color | White to Almost white |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING HAIR CONDITIONING |
| InChI | InChI=1S/C11H13NO4/c1-3-15-10(13)8-5-6-12-9(7-8)11(14)16-4-2/h5-7H,3-4H2,1-2H3 |
| InChIKey | MUUDQLHCIAOWPR-UHFFFAOYSA-N |
| SMILES | C1(C(OCC)=O)=NC=CC(C(OCC)=O)=C1 |
| LogP | 1.92 at 20℃ and pH7.82 |
| Surface tension | 56.3mN/m at 1g/L and 19.7℃ |
| CAS DataBase Reference | 41438-38-4 |
| FDA UNII | 4SN4572M5S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| HS Code | 2933.39.9200 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
2,4-DIETHYLPYRIDINE DICARBOXYLATE price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5518 | Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) | 41438-38-4 | 200mg | $45 | 2026-04-30 | Buy |
| TCI Chemical | D5518 | Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC) | 41438-38-4 | 1g | $135 | 2026-04-30 | Buy |
| Cayman Chemical | 71200 | 2,4-DPD ≥98% | 41438-38-4 | 10mg | $21 | 2026-04-30 | Buy |
| Cayman Chemical | 71200 | 2,4-DPD ≥98% | 41438-38-4 | 25mg | $46 | 2026-04-30 | Buy |
| Cayman Chemical | 71200 | 2,4-DPD ≥98% | 41438-38-4 | 50mg | $86 | 2026-04-30 | Buy |
2,4-DIETHYLPYRIDINE DICARBOXYLATE Chemical Properties,Uses,Production
Uses
Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria[1].
Biological Activity
2,4-dpd is a cell permeable, competitive inhibitor of the oxygen-sensing enzyme hif-α prolyl hydroxylase (hif-ph) [1].hypoxia-inducible factor (hif) is a transcription factor with a key role in cellular responses to hypoxia in a variety of organisms. the hif system plays an important role in angiogenesis, erythropoiesis, energy utilization, glucose/energy metabolism, tumour development, and ischaemic/hypoxic disease. genetic or pharmacological inactivation of the hif hydroxylases results in a constitutive activation of the hif pathway with little or even absent regulation by oxygen remaining. the oxygen-sensing enzyme hif-α prolyl hydroxylase catalyzes hydroxylation of specific prolyl and asparaginyl residues in the regulatory hif-α subunits [2].exposure to 2,4-dpd limited prolyl 4-hydroxylase activity in c. elegans., where their esters are hydrolyzed to form competitors of a -ketoglutarate. 2,4-dpd showed dramatic effects among the progeny. when exposed to a high level of 2,4-dpd (2.7 mm), all progeny died regardless of genotype of c. elegans. the dead embryos arrested at the twofold stage [1].
References
[1] friedman l, higgin j j, moulder g, et al. prolyl 4-hydroxylase is required for viability and morphogenesis in caenorhabditis elegans[j]. proceedings of the national academy of sciences, 2000, 97(9): 4736-4741.
[2] schofield c j, ratcliffe p j. signalling hypoxia by hif hydroxylases[j]. biochemical and biophysical research communications, 2005, 338(1): 617-626.
2,4-DIETHYLPYRIDINE DICARBOXYLATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5995 | 58 |
View Lastest Price from 2,4-DIETHYLPYRIDINE DICARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Diethyl 2,4-Pyridinedicarboxylate
41438-38-4
|
1g | 98.0% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-07-24 | Diethyl pyridine-2,4-dicarboxylate
41438-38-4
|
$1.00-10.00 | 98%+ | 1 ton | Shenzhen Nexconn Pharmatechs Ltd | ||
 |
2026-06-08 | 2,4-DPD
41438-38-4
|
$29.00 | 99.74% | 10g | TargetMol Chemicals Inc. |
-
- Diethyl 2,4-Pyridinedicarboxylate
41438-38-4
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Diethyl pyridine-2,4-dicarboxylate
41438-38-4
- $1.00-10.00
- 98%+
- Shenzhen Nexconn Pharmatechs Ltd
-
- 2,4-DPD
41438-38-4
- $29.00
- 99.74%
- TargetMol Chemicals Inc.
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