Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- CAS No.
- 106246-33-7
- Chemical Name:
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- Synonyms
- M-CDEA;LONZACURE(R) M-CDEA-GS;4-[(4-amino-2-chloro-3,5-diethylphenyl)methyl]-3-chloro-2,6-diethylaniline;JADEWIN MCDEA;LONZACURE(R) M-CDEA;LABOTEST-BB LT00159326;4,4'-METHYLENEBIS(3-CHLORO-2,6-DIETHYLAN;4,4'-Methandiylbis(3-chlor-2,6-diethylanilin);4,4'-Methandiylbis(3-chlor-2,6-diethylanilin);Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
- CBNumber:
- CB1476536
- Molecular Formula:
- C21H28Cl2N2
- Molecular Weight:
- 379.37
- MDL Number:
- MFCD00071551
- MOL File:
- 106246-33-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4,4′-Methylenebis(3-chloro-2,6-diethylaniline) for synthesis | 8.14676 | 25G | $48.5 |
| 4,4'-Methylenebis(3-chloro-2,6-diethylaniline) | M3183 | 25G | $34 |
| Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Asreported | 266375 | 100g | $340 |
| Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Asreported | 266375 | 250g | $528 |
| Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Asreported | 266375 | 500g | $722 |
| More product size | |||
| Melting point | 88 °C |
|---|---|
| Boiling point | 506.4±45.0 °C(Predicted) |
| Density | 1.154±0.06 g/cm3(Predicted) |
| bulk density | 610-650kg/m3 |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Store below +30°C. |
| solubility | 17000 in mg/100g standard fat at 20 ℃ |
| form | powder to lump |
| pka | 3.76±0.25(Predicted) |
| color | White to Light yellow to Light orange |
| Water Solubility | 20μg/L at 20℃ |
| InChI | InChI=1S/C21H28Cl2N2/c1-5-12-9-14(18(22)16(7-3)20(12)24)11-15-10-13(6-2)21(25)17(8-4)19(15)23/h9-10H,5-8,11,24-25H2,1-4H3 |
| InChIKey | VIOMIGLBMQVNLY-UHFFFAOYSA-N |
| SMILES | C(C1=CC(CC)=C(N)C(CC)=C1Cl)C1=CC(CC)=C(N)C(CC)=C1Cl |
| LogP | 6.5 at 20℃ |
| CAS DataBase Reference | 106246-33-7(CAS DataBase Reference) |
| FDA UNII | GN49RAR5P2 |
| EPA Substance Registry System | Benzenamine, 4,4'-methylenebis[3-chloro-2,6-diethyl- (106246-33-7) |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
Bis(4-amino-2-chloro-3,5-diethylphenyl)methane price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.14676 | 4,4′-Methylenebis(3-chloro-2,6-diethylaniline) for synthesis | 106246-33-7 | 25G | $48.5 | 2026-04-30 | Buy |
| TCI Chemical | M3183 | 4,4'-Methylenebis(3-chloro-2,6-diethylaniline) | 106246-33-7 | 25G | $34 | 2026-04-30 | Buy |
| Usbiological | 266375 | Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Asreported | 106246-33-7 | 100g | $340 | 2026-06-03 | Buy |
| Usbiological | 266375 | Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Asreported | 106246-33-7 | 250g | $528 | 2026-06-03 | Buy |
| Usbiological | 266375 | Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Asreported | 106246-33-7 | 500g | $722 | 2026-06-03 | Buy |
Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Chemical Properties,Uses,Production
Chemical Properties
Crystalline Powder
Uses
LONZACURE(R) M-CDEA is an excellent chain extender for elastomeric polyurethanes (PU) and also a curing agent for epoxides (EP). It provides improved mechanical and dynamic properties which cannot be achieved with standard formulations.
Uses
LONZACURE(R) M-CDEA GS is the granulated version of LONZACURE(R) M-CDEA and therefore especially suitable for automatic feeding systems in production lines. It is an excellent chain extender for elastomeric polyurethanes (PU) and also.
Flammability and Explosibility
Not classified
Synthesis
13680-35-8
106246-33-7
The general procedure for the synthesis of 4,4'-methylenebis(2,6-diethylaniline) from 4,4'-methylenebis(3-chloro-2,6-diethylaniline) is as follows: 310 g (1 mol) of 4,4'-methylenebis(2,6-diethylaniline) (MDEA) was added to a three-necked flask fitted with a stirrer, thermometer and dropping funnel. At room temperature, 292.5 g (2.4 mol) of 30% hydrochloric acid solution was slowly added through the dropping funnel and stirred for 15 minutes until complete dissolution. Subsequently, 255.5 g (2.1 mol) of 30% hydrochloric acid solution was added, the reaction temperature was maintained at 45 °C and 262.3 g (2.7 mol) of 35% hydrogen peroxide solution was added slowly dropwise at this temperature and the dropwise process lasted for 2 hours. After completion of the dropwise addition, the reaction temperature was raised to 65°C and maintained for 1 hour. After completion of the reaction, the reaction mixture was cooled to below 10°C and left to stand for 10 hours. The solids and liquids were separated by pressurized filtration. The acidic mother liquor obtained from the separation was stored in an analytical grade vessel for subsequent synthesis of 4,4'-methylenebis(2,6-diethylaniline) (MDEA). The solid obtained by filtration was transferred to a three-necked flask and 200 g of water was added, followed by 280 g of 31% sodium hydroxide solution and stirred until neutralization was complete. After neutralization, the aqueous phase was separated by cooling, and the resulting solid was recrystallized from methanol using conventional methods to obtain white granular crystals, i.e., the target product 4,4'-methylenebis(3-chloro-2,6-diethylaniline). The purity of the product was analyzed by high performance liquid chromatography (HPLC) as 95.8%, in which 3,5-dichloro-4,4'-methylenebis(2,6-diethylaniline) was 0.5% and 3-chloro-4,4'-methylenebis(2,6-diethylaniline) was 1.3%. The above steps were repeated, the aqueous phase was separated after neutralization, the solid obtained was cooled and the fractions with boiling points of 245-250°C (fractions 7-8) were collected using a 30 x 0.5 magnetic ring distillation column. After distillation, the content of 4,4'-methylenebis(3-chloro-2,6-diethylaniline) was increased to 99.3% with a distillation yield of 95%, and this product can meet the demand of high-end polyurethane products.
References
[1] Patent: CN108329212, 2018, A. Location in patent: Paragraph 0040-0045
[2] Patent: CN105693526, 2016, A. Location in patent: Paragraph 0028; 0030; 0031
Bis(4-amino-2-chloro-3,5-diethylphenyl)methane Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Tianjin Zhongxin Chemtech Co., Ltd. | 86-22-66880623 +8618622897568 | sales@tjzxchem.com | China | 572 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6366 | 58 |
View Lastest Price from Bis(4-amino-2-chloro-3,5-diethylphenyl)methane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-09 | Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
106246-33-7
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2026-06-02 | JADEWIN MCDEA
106246-33-7
|
20KG | 98% | 20 tons | QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD | ||
 |
2026-05-28 | Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
106246-33-7
|
$50.00-100.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
106246-33-7
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- JADEWIN MCDEA
106246-33-7
- $0.00
- 98%
- QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD
-
- Bis(4-amino-2-chloro-3,5-diethylphenyl)methane
106246-33-7
- $50.00-100.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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