1-(5-Nitropyridin-2-yl)piperazine
- CAS No.
- 82205-58-1
- Chemical Name:
- 1-(5-Nitropyridin-2-yl)piperazine
- Synonyms
- Palbociclib Impurity 43;5-Nitro-2-piperazinopyridine;1-(5-NITROPYRIDIN-2-YL)PIPERAZINE;1-(5-nitro-2-pyridinyl)-piperazine;Piperazine, 1-(5-nitro-2-pyridinyl)-;1-(5-Nitropyridin-2-yl)piperazine95%;1-(5-Nitropyridin-2-yl)piperazine 95%;1-(5-Nitropyridin-2-yl)piperazine - [N93582];1-(5-Nitropyridin-2-yl)piperazine AldrichCPR;1-(5-nitro-2-pyridinyl)piperazine hydrochloride
- CBNumber:
- CB1674419
- Molecular Formula:
- C9H12N4O2
- Molecular Weight:
- 208.22
- MDL Number:
- MFCD00053059
- MOL File:
- 82205-58-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-(5-Nitropyridin-2-yl)piperazine 95% | OR1756 | 500mg | $21 |
| 1-(5-Nitropyridin-2-yl)piperazine | 024425 | 5.00g | $78 |
| 1-(5-Nitropyridin-2-yl)piperazine | 024425 | 25.00g | $274 |
| 1-(5-Nitropyridin-2-yl)piperazine 95% | N93582 | 250mg | $23 |
| 1-(5-Nitropyridin-2-yl)piperazine 95% | N93582 | 1g | $29 |
| Melting point | 84-85 °C |
|---|---|
| Boiling point | 418.1±40.0 °C(Predicted) |
| Density | 1.278±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| pka | 8.42±0.10(Predicted) |
| Appearance | Light yellow to yellow Solid |
| CAS DataBase Reference | 82205-58-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2933599590 |
1-(5-Nitropyridin-2-yl)piperazine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR1756 | 1-(5-Nitropyridin-2-yl)piperazine 95% | 82205-58-1 | 500mg | $21 | 2026-06-04 | Buy |
| Matrix Scientific | 024425 | 1-(5-Nitropyridin-2-yl)piperazine | 82205-58-1 | 5.00g | $78 | 2026-05-18 | Buy |
| Matrix Scientific | 024425 | 1-(5-Nitropyridin-2-yl)piperazine | 82205-58-1 | 25.00g | $274 | 2026-05-18 | Buy |
| Synthonix | N93582 | 1-(5-Nitropyridin-2-yl)piperazine 95% | 82205-58-1 | 250mg | $23 | 2026-05-06 | Buy |
| Synthonix | N93582 | 1-(5-Nitropyridin-2-yl)piperazine 95% | 82205-58-1 | 1g | $29 | 2026-05-06 | Buy |
1-(5-Nitropyridin-2-yl)piperazine Chemical Properties,Uses,Production
Synthesis
193902-78-2
82205-58-1
Step 2: Synthesis of 1-(5-nitropyridin-2-yl)piperazine (B-3) Compound 1-tert-butylcarbonyl-4-(5-nitro-2-piperidinyl)piperazine (B-2, 19.45 g, 0.0631 mol) was dissolved in dichloromethane (250 mL) and cooled to 0°C. Trifluoroacetic acid (50 mL) was added slowly. The reaction mixture was stirred at room temperature for 16 hours and then concentrated under reduced pressure. The crude product was again dissolved in dichloromethane (250 mL), and the pH was adjusted to alkaline by sequentially adding 1N aqueous NaOH solution (200 mL) and 3N aqueous NaOH solution (100 mL). The organic layer was separated and the aqueous phase was extracted with dichloromethane. The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 1-(5-nitropyridin-2-yl)piperazine (B-3, 13.13 g, 100% yield) as a yellow solid. Mass spectrometry (MS) showed the [M + 1] peak as 209.
References
[1] Patent: WO2010/59606, 2010, A2. Location in patent: Page/Page column 182
[2] Patent: WO2011/31628, 2011, A1. Location in patent: Page/Page column 67
[3] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 4, p. 985 - 988
[4] Tetrahedron Letters, 2011, vol. 52, # 45, p. 5905 - 5909
[5] Patent: WO2006/94840, 2006, A1. Location in patent: Page/Page column 43-44
1-(5-Nitropyridin-2-yl)piperazine Preparation Products And Raw materials
1-(5-Nitropyridin-2-yl)piperazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3967 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Suzhou Victorypharm Co.,Ltd. | +86-13916956214 | sales@victory-pharm.com | China | 1299 | 58 |
View Lastest Price from 1-(5-Nitropyridin-2-yl)piperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | 1-(5-Nitropyridin-2-yl)piperazine
82205-58-1
|
$1.00 | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-11-18 | 1-(5-Nitropyridin-2-yl)piperazine
82205-58-1
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2019-07-12 | 1-(5-Nitropyridin-2-yl)piperazine
82205-58-1
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 1-(5-Nitropyridin-2-yl)piperazine
82205-58-1
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(5-Nitropyridin-2-yl)piperazine
82205-58-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 1-(5-Nitropyridin-2-yl)piperazine
82205-58-1
- $1.00
- 99%
- Career Henan Chemical Co
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