D-P-METHYL SULFONE PHENYL ETHYL SERINATE
- CAS No.
- 36983-12-7
- Chemical Name:
- D-P-METHYL SULFONE PHENYL ETHYL SERINATE
- Synonyms
- D-p-methyI sulfone phenyl ethyl serinate;D-p-Methyl;Florfenicol Impurity 10;Acetildenafil Impurity 3;D-p-Methyl-sulfino phenyl ethyl;D- p-sulfoxylphenylserine ethyl;D-(4-Methylsulfonyl)phenylserineester;D-P-METHYL SULFONE PHENYL ETHYL SERITE;D-Ethyl p-methylsulfonylphenylserinate;Ethyl D-4-(methylsulfinophenyl)serinate
- CBNumber:
- CB1674479
- Molecular Formula:
- C12H17NO5S
- Molecular Weight:
- 287.33
- MDL Number:
- MFCD08274466
- MOL File:
- 36983-12-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| D-p-Methyl Sulfone Phenyl Ethyl Serinate | TRC-M326190-5G | 5g | $765 |
| D-p-Methyl Sulfone Phenyl Ethyl Serinate | TRC-M326190-1G | 1g | $189 |
| D-p-Methyl sulfone phenyl ethyl serinate 95% | J93506 | 5g | $12 |
| D-p-Methyl sulfone phenyl ethyl serinate 95% | J93506 | 25g | $22 |
| D-p-Methyl sulfone phenyl ethyl serinate 95% | J93506 | 100g | $51 |
| More product size | |||
| Melting point | 135-137°C |
|---|---|
| Boiling point | 515.0±50.0 °C(Predicted) |
| Density | 1.309 |
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | Chloroform |
| form | Solid |
| pka | 10.57±0.45(Predicted) |
| color | White |
| optical activity | 1.00°(C=0.01g/mL, MEOH, 589nm) |
| InChI | InChI=1/C12H17NO5S/c1-3-18-12(15)10(13)11(14)8-4-6-9(7-5-8)19(2,16)17/h4-7,10-11,14H,3,13H2,1-2H3/t10-,11+/s3 |
| InChIKey | CEEHCOWSYFANRT-WQVXQJEGNA-N |
| SMILES | [C@@H](C1C=CC(S(=O)(=O)C)=CC=1)(O)[C@@H](N)C(=O)OCC |&1:0,12,r| |
| CAS DataBase Reference | 36983-12-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
D-P-METHYL SULFONE PHENYL ETHYL SERINATE price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-M326190-5G | D-p-Methyl Sulfone Phenyl Ethyl Serinate | 36983-12-7 | 5g | $765 | 2026-06-03 | Buy |
| TRC | TRC-M326190-1G | D-p-Methyl Sulfone Phenyl Ethyl Serinate | 36983-12-7 | 1g | $189 | 2026-06-03 | Buy |
| AK Scientific | J93506 | D-p-Methyl sulfone phenyl ethyl serinate 95% | 36983-12-7 | 5g | $12 | 2026-06-04 | Buy |
| AK Scientific | J93506 | D-p-Methyl sulfone phenyl ethyl serinate 95% | 36983-12-7 | 25g | $22 | 2026-06-04 | Buy |
| AK Scientific | J93506 | D-p-Methyl sulfone phenyl ethyl serinate 95% | 36983-12-7 | 100g | $51 | 2026-06-04 | Buy |
D-P-METHYL SULFONE PHENYL ETHYL SERINATE Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Florfenicol intermediate.
Synthesis
5398-77-6
623-33-6
31925-27-6
GENERAL STEPS: 500 g (15.6 mol) of methanol was added to a 1000 ml three-necked flask. Under stirring conditions, 73.9 g (0.53 mol) of ethyl glycinate hydrochloride was added and the temperature was slowly raised to 50-55°C until the ethyl glycinate hydrochloride was completely dissolved. Subsequently, 67.5 g (0.27 mol) of copper sulfate pentahydrate was added to this solution and stirring was continued until complete dissolution and stirring was maintained at 50-55°C for 0.5 hr. Next, triethylamine was added dropwise to the reaction system and the pH was adjusted to 8.5-9.0. Then, 92 g (0.5 mol) of p-methylsulfonylbenzaldehyde was added, and the reaction temperature was maintained at 50-55 °C and the pH was maintained between 8.5-9.0 by adding triethylamine. During the reaction, the progress of the reaction was monitored by HPLC, and the reaction was judged to be complete when the percentage of peak area of p-methylsulfonylbenzaldehyde was less than 2%. At the end of the reaction, methanol was recovered by decompression distillation, and the temperature inside the reaction flask was controlled to be no more than 50 °C during the distillation process. After the recovery of methanol, 600 g of water was added to the reaction flask, and after sufficient stirring, 146.7 g of ethyl 3-(p-toluenesulfonylphenyl)serinate was obtained by centrifugation, with a moisture content of 10.0%, a purity of 97.2% and a yield of 92%.
References
[1] Patent: CN108373430, 2018, A. Location in patent: Paragraph 0017; 0040; 0045-0059
D-P-METHYL SULFONE PHENYL ETHYL SERINATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
View Lastest Price from D-P-METHYL SULFONE PHENYL ETHYL SERINATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | D-P-Methyl Sulfone Phenyl Ethyl Serinate
36983-12-7
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2024-12-24 | D-threo-beta-Methylsulfonylphenylserine ethyl ester
36983-12-7
|
1g | 99.99% | 20 tons | airuikechemical co., ltd. | ||
 |
2021-07-02 | D-p-Methyl Sulfone Phenyl Ethyl Serinate
36983-12-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- D-P-Methyl Sulfone Phenyl Ethyl Serinate
36983-12-7
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- D-threo-beta-Methylsulfonylphenylserine ethyl ester
36983-12-7
- 99.99%
- airuikechemical co., ltd.
-
- D-p-Methyl Sulfone Phenyl Ethyl Serinate
36983-12-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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