Butyl chloroformate
- CAS No.
- 592-34-7
- Chemical Name:
- Butyl chloroformate
- Synonyms
- butyl carbonochloridate;N-BUTYL CHLOROFORMATE;BUTYL CHLOROFORMATE;n-Buty chloroformate;Butyl chlorocarbonate;Butyl chloridocarbonate;Butoxycarbonyl chloride;BUTYL CHLOROCARBOXYLATE;N-Butyl Chlorocarbonate;Butyl chloroformate,98%
- CBNumber:
- CB1692042
- Molecular Formula:
- C5H9ClO2
- Molecular Weight:
- 136.58
- MDL Number:
- MFCD00000650
- MOL File:
- 592-34-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Butyl chloroformate 98% | 184462 | 100g | $145 |
| Butyl Chloroformate | TRC-B692725-5G | 5g | $91 |
| Butyl Chloroformate | TRC-B692725-25G | 25g | $122 |
| Butyl Chloroformate | TRC-B692725-100G | 100g | $147 |
| Butyl chloroformate | FB05915 | 50g | $150 |
| More product size | |||
| Melting point | -70 °C |
|---|---|
| Boiling point | 142 °C(lit.) |
| Density | 1.074 g/mL at 25 °C(lit.) |
| vapor pressure | 2.42 psi ( 20 °C) |
| refractive index |
n |
| Flash point | 77 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Clear |
| Water Solubility | DECOMPOSES |
| Sensitive | Moisture Sensitive |
| BRN | 605635 |
| LogP | 1.895 (est) |
| CAS DataBase Reference | 592-34-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 3TGX130CB0 |
| NIST Chemistry Reference | Carbonochloridic acid, butyl ester(592-34-7) |
| EPA Substance Registry System | n-Butyl chloroformate (592-34-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H330-H314-H226 | |||||||||
| Precautionary statements | P501-P240-P260-P210-P233-P243-P241-P242-P271-P264-P280-P284-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P233-P403+P235-P405 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 10-23-34 | |||||||||
| Safety Statements | 26-36-45 | |||||||||
| RIDADR | UN 2743 | |||||||||
| WGK Germany | 1 | |||||||||
| F | 10-19 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29159020 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Butyl chloroformate price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 184462 | Butyl chloroformate 98% | 592-34-7 | 100g | $145 | 2026-04-30 | Buy |
| TRC | TRC-B692725-5G | Butyl Chloroformate | 592-34-7 | 5g | $91 | 2026-06-03 | Buy |
| TRC | TRC-B692725-25G | Butyl Chloroformate | 592-34-7 | 25g | $122 | 2026-06-03 | Buy |
| TRC | TRC-B692725-100G | Butyl Chloroformate | 592-34-7 | 100g | $147 | 2026-06-03 | Buy |
| Biosynth | FB05915 | Butyl chloroformate | 592-34-7 | 50g | $150 | 2026-06-04 | Buy |
Butyl chloroformate Chemical Properties,Uses,Production
Chemical Properties
clear liquid
Uses
Butyl Chloroformate is a reactant in the preparation of Lapatinib derivatives as HER1/HER2 targeting antitumor drugs.
General Description
A colorless liquid. Flash point near 70°F. Very toxic by inhalation. Denser than water. Used to make other chemicals.
Air & Water Reactions
Highly flammable. Decomposes exothermically in water to give hydrochloric acid and organic acids.
Reactivity Profile
Butyl chloroformate is incompatible with bases (including amines), with water, with strong oxidizing agents, with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Health Hazard
Inhalation of vapor irritates nose and throat and can cause delayed pulmonary edema. Liquid irritates eyes and causes severe skin burns and irreversible skin damage if allowed to remain. Can cause blindness. Ingestion causes burns of mouth and stomach.
Flammability and Explosibility
Flammable
Synthesis
The n-butyl chloroformate was prepared as follows: 1580g of n-butanol (M=74) was preheated to 100C, added from the upper inlet of the reaction distillation tower using a stratospheric pump, and fully contacted with the phosgene gas (0.5MPa, M=98.9) entering from the lower inlet in the reaction section, which was 100C. The liquid hydrogen chloride and the excess of hydrogen chloride were separated by deep condensation at -40C through a heat exchanger into the reaction distillation tower for reuse. The generated hydrogen chloride and excess phosgene enter the subsequent recovery unit through the top of the tower and are separated by deep condensation at -40C. The liquid phosgene passes through a heat exchanger into the reaction distillation tower for reuse, and the hydrogen chloride gas is passed into a 1.0 wt% NaOH aqueous solution for absorption. The n-butyl chloroformate as a single product stream passes through the tower kettle into the storage tank for subsequent use. The composition of the reaction solution was analyzed by gas chromatography, which showed that the conversion of butanol was >99.9% and the selectivity of chloroformate was >99.9%.
Butyl chloroformate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 | sales@amoychem.com | China | 6366 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hebei Miaobian Biotechnology Co., Ltd | 17733850068 | CHINA | 967 | 58 | |
| Shanghai Yudiao Chemistry Technology Co.,Ltd | 02137285211 18964703211 | info@yudiaochem.com | CHINA | 238 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15079 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from Butyl chloroformate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | Butyl chloroformate
592-34-7
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2019-07-06 | Butyl chloroformate
592-34-7
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-
- Butyl chloroformate
592-34-7
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Butyl chloroformate
592-34-7
- $1.00
- 99%
- Career Henan Chemical Co
