3,5-Dimethyl-4-methoxybenzoic acid
- CAS No.
- 21553-46-8
- Chemical Name:
- 3,5-Dimethyl-4-methoxybenzoic acid
- Synonyms
- 3,5-DIMETHYL-P-ANISIC ACID;TB023;3,5-DIMETHYL ANISIC ACID;3,5-DIMETHYL-4-ANISIC ICD;3,5-DIMETHYL-4-ANISIC ACID;3,5-Dimethyl-4-Methoxybenzoic;4-methoxy-3,5-dimethylbenzoate;3,5-Dimethyl-p-anisic acid,98%;3,5-DIMETHYL-P-ANISIC ACID 98%;,5-diMethyl-4-Methoxybenzoic acid
- CBNumber:
- CB1780569
- Molecular Formula:
- C10H12O3
- Molecular Weight:
- 180.2
- MDL Number:
- MFCD00020309
- MOL File:
- 21553-46-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3,5-Dimethyl-4-methoxybenzoic acid 97% | 638692 | 1g | $87.4 |
| 3,5-Dimethyl-4-methoxybenzoic acid 97% | 638692 | 5g | $192 |
| 4-Methoxy-3,5-dimethylbenzoic Acid >98.0%(GC)(T) | M2139 | 1g | $32 |
| 4-Methoxy-3,5-dimethylbenzoic Acid >98.0%(GC)(T) | M2139 | 5g | $90 |
| 3,5-Dimethyl-4-methoxybenzoic acid | FD03324 | 5g | $150 |
| More product size | |||
| Melting point | 191-195 °C (lit.) |
|---|---|
| Boiling point | 253.02°C (rough estimate) |
| Density | 1.1185 (rough estimate) |
| refractive index | 1.5392 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 4.61±0.10(Predicted) |
| form | Crystalline Solid |
| color | White to brown |
| InChI | 1S/C10H12O3/c1-6-4-8(10(11)12)5-7(2)9(6)13-3/h4-5H,1-3H3,(H,11,12) |
| InChIKey | WXVQURJGDUNJCS-UHFFFAOYSA-N |
| SMILES | COc1c(C)cc(cc1C)C(O)=O |
| CAS DataBase Reference | 21553-46-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H319 | |||||||||
| Precautionary statements | P301+P310+P330-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29189900 | |||||||||
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
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| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 |
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| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
3,5-Dimethyl-4-methoxybenzoic acid price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 638692 | 3,5-Dimethyl-4-methoxybenzoic acid 97% | 21553-46-8 | 1g | $87.4 | 2022-05-15 | Buy |
| Sigma-Aldrich | 638692 | 3,5-Dimethyl-4-methoxybenzoic acid 97% | 21553-46-8 | 5g | $192 | 2022-05-15 | Buy |
| TCI Chemical | M2139 | 4-Methoxy-3,5-dimethylbenzoic Acid >98.0%(GC)(T) | 21553-46-8 | 1g | $32 | 2026-04-30 | Buy |
| TCI Chemical | M2139 | 4-Methoxy-3,5-dimethylbenzoic Acid >98.0%(GC)(T) | 21553-46-8 | 5g | $90 | 2026-04-30 | Buy |
| Biosynth | FD03324 | 3,5-Dimethyl-4-methoxybenzoic acid | 21553-46-8 | 5g | $150 | 2026-06-04 | Buy |
3,5-Dimethyl-4-methoxybenzoic acid Chemical Properties,Uses,Production
Chemical Properties
white to brown crystalline solid
Synthesis
152775-45-6
21553-46-8
General procedure for the synthesis of 3,5-dimethyl-4-methoxybenzoic acid from 4-methoxy-3,5-dimethylbenzenecarbonitrile: 4-methoxy-3,5-dimethylbenzenecarbonitrile (1664 mg) was suspended in ethanol (32 mL), to which 8M NaOH solution (163 mL) was added. The mixture was placed in a pressure reactor and the reaction was stirred at 120 °C overnight. Upon completion of the reaction, ethanol was removed by rotary evaporation. Water was added to the residue and the aqueous solution was washed with ether to remove non-polar impurities. Subsequently, the aqueous layer was acidified with concentrated hydrochloric acid to pH < 2, at which point the target product precipitated as a solid. The acidified aqueous layer was extracted with ethyl acetate and the organic phases were combined and washed sequentially with water and saturated brine. The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated to afford 3,5-dimethyl-4-methoxybenzoic acid as a white solid in 99% yield.LRMS (m/z): 181 ([M+H]+).HPLC retention time: 5.52 min (Method B).
References
[1] Patent: WO2011/144338, 2011, A1. Location in patent: Page/Page column 92
[2] Patent: EP2390252, 2011, A1. Location in patent: Paragraph 0449; 0450
3,5-Dimethyl-4-methoxybenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29793 | 58 |
| Shanghai zaiqi biology technology co., ltd | +86-21-54824098 13817598959 | sales@chemzq.com | CHINA | 136 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14303 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 3,5-Dimethyl-4-methoxybenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 3,5-Dimethyl-4-methoxybenzoic acid
21553-46-8
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2022-01-15 | 3,5-Dimethyl-4-methoxybenzoicacid
21553-46-8
|
1KG | 98.1% | 100 tons | Honest Joy Holdings Limited
|
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 |
2020-02-01 | 3,5-Dimethyl-4-methoxybenzoic acid
21553-46-8
|
$3.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- 3,5-Dimethyl-4-methoxybenzoic acid
21553-46-8
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3,5-Dimethyl-4-methoxybenzoicacid
21553-46-8
- $0.00
- 98.1%
- Honest Joy Holdings Limited
-
- 3,5-Dimethyl-4-methoxybenzoic acid
21553-46-8
- $3.00
- 98%
- Career Henan Chemical Co
