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ChemicalBook >> CAS DataBase List >>METHYLSULFONYLACETONE

METHYLSULFONYLACETONE

CAS No.
5000-46-4
Chemical Name:
METHYLSULFONYLACETONE
Synonyms
NSC 35395;1-Mesyl-2-propanone;METHYLSULFONYLACETONE;METHANESULFONYLACETONE;Methylsulphonylacetone;METHANESULPHONYLACETONE;1-(Methylsulfonyl)acetone;2-Oxopropylmethyl sulfone;1-(methylsulphonyl)acetone;Methylsulfonylacetone, 98+%
CBNumber:
CB1783045
Molecular Formula:
C4H8O3S
Molecular Weight:
136.17
MDL Number:
MFCD00014745
MOL File:
5000-46-4.mol
MSDS File:
SDS
Last updated:2026-05-27 23:45:05
Product description Number Pack Size Price
Methanesulfonylacetone 544639 10g $96.7
Methanesulfonylacetone Asreported 283030 5g $366
Methanesulfonylacetone Asreported 283030 10g $512
Methanesulfonylacetone Asreported 283030 25g $761
Methanesulfonylacetone Asreported 283030 50g $1018

METHYLSULFONYLACETONE Properties

Melting point 48-52 °C (lit.)
Boiling point 300.8±25.0 °C(Predicted)
Density 1.208±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp. 2-8°C
form powder or crystals
Appearance White to yellow Solid
Water Solubility Insoluble in water.
BRN 1754113
InChI 1S/C4H8O3S/c1-4(5)3-8(2,6)7/h3H2,1-2H3
InChIKey NWEYGXQKFVGUFR-UHFFFAOYSA-N
SMILES CC(=O)CS(C)(=O)=O
CAS DataBase Reference 5000-46-4(CAS DataBase Reference)
FDA UNII 3R8R8J4V2L
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
HS Code  29302000
Storage Class 11 - Combustible Solids
NFPA 704
1
0 0

METHYLSULFONYLACETONE price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 544639 Methanesulfonylacetone 5000-46-4 10g $96.7 2026-04-30 Buy
Usbiological 283030 Methanesulfonylacetone Asreported 5000-46-4 5g $366 2026-06-03 Buy
Usbiological 283030 Methanesulfonylacetone Asreported 5000-46-4 10g $512 2026-06-03 Buy
Usbiological 283030 Methanesulfonylacetone Asreported 5000-46-4 25g $761 2026-06-03 Buy
Usbiological 283030 Methanesulfonylacetone Asreported 5000-46-4 50g $1018 2026-06-03 Buy
Product number Packaging Price Buy
544639 10g $96.7 Buy
283030 5g $366 Buy
283030 10g $512 Buy
283030 25g $761 Buy
283030 50g $1018 Buy

METHYLSULFONYLACETONE Chemical Properties,Uses,Production

Uses

Methylsulfonylacetone is used as reactant for Stereoselective preparation of chiral cyclic ketones. It is used in the Preparation of poly-substituted pyridines. It aids for Gold-catalyzed Friedlander cyclocondensation reaction. It is used as reactant in Radical homoallylation reactions, multicomponent cyclocondensation with aldehydes and aminoazoles.

General Description

Methanesulfonylacetone is a sulfonyl group-containing active methylene compound. It can react with Baylis–Hillman acetates in dimethylformamide/potassium carbonate system to form ortho-hydroxyacetophenone derivatives.

124-63-0
78-95-5
5000-46-4
Synthesis of METHYLSULFONYLACETONE from Methanesulfonyl chloride and Chloroacetone

METHYLSULFONYLACETONE Preparation Products And Raw materials

METHYLSULFONYLACETONE Suppliers

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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Hebei Chuanghai Biotechnology Co., Ltd
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HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43333 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.
+8618950047208 ellena@amitychem.com China 43414 58
DAYANG CHEM (HANGZHOU) CO.,LTD
+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131956 58
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. +86-21-54098501 sales@sinch.com.cn China 11598 64
1-METHANESULPHONYLPROPAN-2-ONE Methylsulfonylacetone, 98+% Methanesulfonylacetone, 98+% METHYLSULFONYLACETONE METHANESULFONYLACETONE METHANESULPHONYLACETONE Methylsulphonylacetone 1-(methylsulphonyl)acetone Methanesulphonylacetone,98+% 1-(Methylsulfonyl)-2-propanone 1-(Methylsulfonyl)acetone 1-Mesyl-2-propanone 2-Oxopropylmethyl sulfone Methyl(2-oxopropyl) sulfone 1-(Methylsulfonyl)propan-2-one NSC 35395 1-methanesulfonyl-propan-2-one 2-Propanone, 1-(methylsulfonyl)- 5000-46-4 CH3COCH2SO2CH3 Building Blocks Organic Building Blocks Sulfones Sulfur Compounds Organic Building Blocks Sulfones Sulfur Compounds
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