ChemicalBook >> CAS DataBase List >>Pomalidomide-C6-NH2?hydrochloride
Pomalidomide-C6-NH2?hydrochloride
- CAS No.
- 2375194-37-7
- Chemical Name:
- Pomalidomide-C6-NH2?hydrochloride
- Synonyms
- 4-((6-aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;Poma-C6-NH2·HCl;Thalidomide-NH-C6-NH2 HCl;Pomalidomide 4'-alkylC6-amine;Pomalidomide-C6-NH2?hydrochloride;Thalidomide-NH-C6-NH2 hydrochloride;Pomalidomide-C6-amine hydrochloride;Pomalidomide-C6-NH2 hydrochloride;Thalidomide-NH-C6-NH2 HCl/Pomalidomide-C6-NH2 hydrochloride;4-(6-aminohexylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
- CBNumber:
- CB18713286
- Molecular Formula:
- C19H25ClN4O4
- Molecular Weight:
- 408.88
- MDL Number:
- MOL File:
- 2375194-37-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 23:48:54
| Product description | Number | Pack Size | Price |
| Pomalidomide 4''-alkylC6-amine (hydrochloride) ≥98% | 39985 | 25mg | $83 |
| Pomalidomide 4''-alkylC6-amine (hydrochloride) ≥98% | 39985 | 50mg | $125 |
| Pomalidomide 4''-alkylC6-amine (hydrochloride) ≥98% | 39985 | 100mg | $231 |
| Pomalidomide-C6-amine hydrochloride | AVD19437 | 5mg | $275 |
| Pomalidomide-C6-amine hydrochloride | AVD19437 | 10mg | $412.5 |
| storage temp. | 2-8°C |
|---|---|
| solubility |
DMSO: Soluble Methanol: Soluble |
| form | Solid |
| color | Light yellow to yellow |
| InChI | 1S/C19H24N4O4.ClH/c20-10-3-1-2-4-11-21-13-7-5-6-12-16(13)19(27)23(18(12)26)14-8-9-15(24)22-17(14)25;/h5-7,14,21H,1-4,8-11,20H2,(H,22,24,25);1H |
| InChIKey | PBGMRXNTLPSDNR-UHFFFAOYSA-N |
| SMILES | O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3NCCCCCCN)=O)NC1=O.Cl |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| WGK Germany | WGK 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Repr. 1B |
Pomalidomide-C6-NH2?hydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 39985 | Pomalidomide 4''-alkylC6-amine (hydrochloride) ≥98% | 2375194-37-7 | 25mg | $83 | 2026-04-30 | Buy |
| Cayman Chemical | 39985 | Pomalidomide 4''-alkylC6-amine (hydrochloride) ≥98% | 2375194-37-7 | 50mg | $125 | 2026-04-30 | Buy |
| Cayman Chemical | 39985 | Pomalidomide 4''-alkylC6-amine (hydrochloride) ≥98% | 2375194-37-7 | 100mg | $231 | 2026-04-30 | Buy |
| Biosynth | AVD19437 | Pomalidomide-C6-amine hydrochloride | 2375194-37-7 | 5mg | $275 | 2026-06-04 | Buy |
| Biosynth | AVD19437 | Pomalidomide-C6-amine hydrochloride | 2375194-37-7 | 10mg | $412.5 | 2026-06-04 | Buy |
Pomalidomide-C6-NH2?hydrochloride Chemical Properties,Uses,Production
Uses
Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
reaction suitability
reactivity: carboxyl reactive
reagent type: ligand-linker conjugate
IC 50
Cereblon
References
[1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277
[3] ZHIQIANG SUN . Discovery of pomalidomide-based PROTACs for selective degradation of histone deacetylase 8[J]. European Journal of Medicinal Chemistry, 2022, 239: Article 114544. DOI: 10.1016/j.ejmech.2022.114544
Pomalidomide-C6-NH2?hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Pomalidomide-C6-NH2?hydrochloride Suppliers
Global( 49)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9545 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11780 | 60 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16101 | 64 |
| ChemShuttle, Inc. | 0510-83588313-811 18800520310 | sales@chemshuttle.com | China | 2999 | 62 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89686 | 60 |
View Lastest Price from Pomalidomide-C6-NH2?hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Pomalidomide-C6-NH2 hydrochloride
2375194-37-7
|
250mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- Pomalidomide-C6-NH2 hydrochloride
2375194-37-7
- $0.00
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
2375194-37-7(Pomalidomide-C6-NH2?hydrochloride)Related Search:
E3 ligase Ligand-Linker Conjugates 49
Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide
Pomalidomide-C6-PEG3-butyl iodide
E3 ligase Ligand-Linker Conjugates 55
1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
Pomalidomide-6-2-2-6-N3
Pomalidomide-amido-C1-Br
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
4-[(8-Aminooctyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
1of4
Pomalidomide-C6-NH2?hydrochloride
Thalidomide-NH-C6-NH2 HCl
Thalidomide-NH-C6-NH2 hydrochloride
E3 Ligase Ligand-Linker Conjugates,inhibit,Thalidomide-NH-C-6-NH2 hydrochloride,ThalidomideNHC6NH2 hydrochloride,Thalidomide NH C6 NH2 hydrochloride,Inhibitor
4-((6-Aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride, Crosslinker?E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
Poma-C6-NH2·HCl
Pomalidomide 4'-alkylC6-amine
4-(6-aminohexylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Pomalidomide-C6-NH2 hydrochloride
Pomalidomide-C6-amine hydrochloride
Thalidomide-NH-C6-NH2 HCl/Pomalidomide-C6-NH2 hydrochloride
1H-Isoindole-1,3(2H)-dione, 4-[(6-aminohexyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
4-((6-aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
2375194-37-7
