6-BROMO-BENZO[B]THIOPHENE
![6-BROMO-BENZO[B]THIOPHENE Structure](CAS/GIF/17347-32-9.gif)
- CAS No.
- 17347-32-9
- Chemical Name:
- 6-BROMO-BENZO[B]THIOPHENE
- Synonyms
- 6-bromobenzothiophene;6-Bromo-1-benzothiophene;6-BROMO-BENZO[B]THIOPHENE;Benzo[b]thiophene, 6-bromo-;6-Bromobenzo[b]thiophene;6-Bromobenzothiophene in isooctane;Brexpiprazole Impurity 20 ,6-bromobenzo[b]thiophene
- CBNumber:
- CB21477838
- Molecular Formula:
- C8H5BrS
- Molecular Weight:
- 213.09
- MDL Number:
- MFCD11226847
- MOL File:
- 17347-32-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-Bromobenzo[b]thiophene 97% | 738328 | 1g | $136 |
| 6-Bromobenzo[b]thiophene >95.0%(GC) | B5523 | 1g | $100 |
| 6-Bromobenzothiophene 97% | AS31534 | 1g | $21 |
| 6-Bromobenzothiophene 97% | AS31534 | 5g | $46 |
| 6-Bromobenzothiophene 97% | AS31534 | 25g | $167 |
| More product size | |||
| Melting point | 56.0 to 60.0 °C |
|---|---|
| Boiling point | 140°C/30mmHg(lit.) |
| Density | 1.649±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Light yellow |
| InChI | InChI=1S/C8H5BrS/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5H |
| InChIKey | OQIMJOXSDVGEBU-UHFFFAOYSA-N |
| SMILES | C12=CC(Br)=CC=C1C=CS2 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319-H413 | |||||||||
| Precautionary statements | P273-P301+P312+P330-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2934999090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 4 Eye Irrit. 2 |
|||||||||
| NFPA 704 |
|
6-BROMO-BENZO[B]THIOPHENE price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 738328 | 6-Bromobenzo[b]thiophene 97% | 17347-32-9 | 1g | $136 | 2026-04-30 | Buy |
| TCI Chemical | B5523 | 6-Bromobenzo[b]thiophene >95.0%(GC) | 17347-32-9 | 1g | $100 | 2026-04-30 | Buy |
| Activate Scientific | AS31534 | 6-Bromobenzothiophene 97% | 17347-32-9 | 1g | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS31534 | 6-Bromobenzothiophene 97% | 17347-32-9 | 5g | $46 | 2026-06-04 | Buy |
| Activate Scientific | AS31534 | 6-Bromobenzothiophene 97% | 17347-32-9 | 25g | $167 | 2026-06-04 | Buy |
6-BROMO-BENZO[B]THIOPHENE Chemical Properties,Uses,Production
Chemical Properties
off-white powder
Uses
6-Bromobenzo[b]thiophene is a reagent for the synthesis of aminobenzo[b]thiophene 1,1-dioxides as STAT3 inhibitors with antitumor activities being an attractive therapeutic target for cancer therapy.
Synthesis
![6-BROMO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID](/CAS/GIF/19075-58-2.gif)
19075-58-2
![6-BROMO-BENZO[B]THIOPHENE](/CAS/GIF/17347-32-9.gif)
17347-32-9
Part C. Preparation of 6-bromobenzo[b]thiophene. 6-Bromobenzo[b]thiophene-2-carboxylic acid (0.70 g, 2.73 mmol) from Part B was mixed with DBU (1.35 mL, 8.94 mmol) in DMA (6 mL) in a sealed tube and heated in a microwave reactor for 70 min at 200 °C. After completion of the reaction, the resulting dark solution was diluted with 1 M HCl (20 mL) and extracted with dichloromethane (2 x 20 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using dichloromethane as eluent to afford 6-bromobenzo[b]thiophene as an oil (0.484 g, 83% yield).
References
[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 1, p. 264 - 281
[2] Tetrahedron Letters, 2004, vol. 45, # 52, p. 9645 - 9647
[3] Patent: WO2009/39134, 2009, A1. Location in patent: Page/Page column 159
[4] Patent: WO2012/149413, 2012, A1. Location in patent: Page/Page column 59
[5] European Journal of Medicinal Chemistry, 2017, vol. 125, p. 538 - 550
6-BROMO-BENZO[B]THIOPHENE Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5742 | 58 |
View Lastest Price from 6-BROMO-BENZO[B]THIOPHENE manufacturers
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|---|---|---|---|---|---|---|---|---|
![6-BROMO-BENZO[B]THIOPHENE pictures](https://img.chemicalbook.com/ProductImageEN/2019-12/Small/7ef90d64-091a-477e-ac2c-b322298276ca.gif) |
2019-12-25 | 6-BROMO-BENZO[B]THIOPHENE
17347-32-9
|
1KG | 95%-99% | 500kg | Career Henan Chemical Co |
-
- 6-BROMO-BENZO[B]THIOPHENE
17347-32-9
- $0.10
- 95%-99%
- Career Henan Chemical Co
