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ChemicalBook >> CAS DataBase List >>N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE

CAS No.
72791-76-5
Chemical Name:
N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE
Synonyms
benzyl bis(2-chloroethyl)carbamate;Benzyl bis(2-chloroethyl);N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE;benzyl N,N-bis(2-chloroethyl)carbamate;bis(2-chloroethyl)carbamic acid benzyl ester;CarbaMic acid,N,N-bis(2-chloroethyl)-, phenylMethyl ester
CBNumber:
CB2174385
Molecular Formula:
C12H15Cl2NO2
Molecular Weight:
276.16
MDL Number:
MFCD06858694
MOL File:
72791-76-5.mol
MSDS File:
SDS
Last updated:2026-05-27 23:58:27
Product description Number Pack Size Price
Benzyl bis(2-chloroethyl)carbamate XCA79176 50mg $1508
Benzyl bis(2-chloroethyl)carbamate XCA79176 0.5g $4312.9
Benzyl bis(2-chloroethyl)carbamate 95% AS113736 1g $21
Benzyl bis(2-chloroethyl)carbamate 95% AS113736 5g $53
Benzyl bis(2-chloroethyl)carbamate 95% AS113736 25g $110
More product size

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE Properties

Boiling point 376.9±42.0 °C(Predicted)
Density 1.245±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka -1.78±0.70(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth XCA79176 Benzyl bis(2-chloroethyl)carbamate 72791-76-5 50mg $1508 2026-06-05 Buy
Biosynth XCA79176 Benzyl bis(2-chloroethyl)carbamate 72791-76-5 0.5g $4312.9 2026-06-05 Buy
Activate Scientific AS113736 Benzyl bis(2-chloroethyl)carbamate 95% 72791-76-5 1g $21 2026-06-04 Buy
Activate Scientific AS113736 Benzyl bis(2-chloroethyl)carbamate 95% 72791-76-5 5g $53 2026-06-04 Buy
Activate Scientific AS113736 Benzyl bis(2-chloroethyl)carbamate 95% 72791-76-5 25g $110 2026-06-04 Buy
Product number Packaging Price Buy
XCA79176 50mg $1508 Buy
XCA79176 0.5g $4312.9 Buy
AS113736 1g $21 Buy
AS113736 5g $53 Buy
AS113736 25g $110 Buy

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE Chemical Properties,Uses,Production

Synthesis

Bis(2-chloroethyl)amine hydrochloride

821-48-7

Benzyl chloroformate

501-53-1

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE

72791-76-5

Bis(2-chloroethyl)amine hydrochloride (5 g, 0.028 mol) was suspended in 30 ml of anhydrous dichloromethane under cooling in an ice water bath and stirring. Benzyl chloroformate (5.1 g, 0.03 mol) was added slowly dropwise with a controlled dropwise time of 10 min. Subsequently, triethylamine (6.46 g, 0.063 mol) was added dropwise over 1 hour. The reaction mixture was continued to be stirred at room temperature for 1 hour. Upon completion of the reaction, the reaction was quenched by the addition of water (10 ml) and stirring was continued for 15 minutes. The organic phase (dichloromethane layer) was separated and washed sequentially with 1M HCl (10 ml) and saturated saline (10 ml), dried anhydrically and concentrated under reduced pressure to give the oily target product benzyl bis(dichloroethyl)aminocarboxylate (7 g, 95.5% yield, 80% purity).

References

[1] Organic Letters, 2009, vol. 11, # 2, p. 449 - 452
[2] Patent: US2009/143582, 2009, A1. Location in patent: Page/Page column 8
[3] Patent: US2015/105384, 2015, A1. Location in patent: Paragraph 0174; 0175
[4] Patent: WO2016/57779, 2016, A2. Location in patent: Page/Page column 63
[5] Patent: KR2017/43091, 2017, A. Location in patent: Paragraph 0693-0696

821-48-7
501-53-1
72791-76-5
Synthesis of N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE from Bis(2-chloroethyl)amine hydrochloride and Benzyl chloroformate

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE Preparation Products And Raw materials

Global( 59)Suppliers
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Capot Chemical Co.,Ltd.
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Career Henan Chemica Co
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Aladdin Scientific
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Aladdin Scientific
tp@aladdinsci.com United States 52923 58
Suzhou ARTK Medchem Co., Ltd.
+8618118463618 sales1@artkmedchem.com China 39021 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131956 58

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE Spectrum

N-CBZ-N,N-BIS(2-CHLOROETHYL)AMINE bis(2-chloroethyl)carbamic acid benzyl ester CarbaMic acid,N,N-bis(2-chloroethyl)-, phenylMethyl ester Benzyl bis(2-chloroethyl) benzyl N,N-bis(2-chloroethyl)carbamate benzyl bis(2-chloroethyl)carbamate 72791-76-5 pharmacetical
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