ChemicalBook >> CAS DataBase List >>3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID
3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID
![3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID Structure](CAS/GIF/143438-91-9.gif)
- CAS No.
- 143438-91-9
- Chemical Name:
- 3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID
- Synonyms
- RARECHEM AK HW 0018;3-TrifluoroMethyl-DL-b-phenylalanine;3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE;(R)-1-(4-chloro-2-fluorophenyl)propan-1-amine;Benzenepropanoic acid, β-amino-3-(trifluoromethyl)-;3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID;3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID;DL-3-Amino-3-(3-trifluoromethylphenyl)propanoic acid;DL-3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID;(RS)-3-Amino-3-(3-trifluoromethylphenyl)-propionic acid
- CBNumber:
- CB2203250
- Molecular Formula:
- C10H10F3NO2
- Molecular Weight:
- 233.19
- MDL Number:
- MFCD02653329
- MOL File:
- 143438-91-9.mol
- MSDS File:
- SDS
Last updated:2026-05-27 23:59:07
| Product description | Number | Pack Size | Price |
| 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | PC10262 | 1g | $85 |
| 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | PC10262 | 1g | $85 |
| 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | AS34275 | 1g | $43 |
| 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | AS34275 | 5g | $156 |
| 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | AS34275 | 25g | $526 |
| Melting point | 210-212°C |
|---|---|
| Boiling point | 295.2±40.0 °C(Predicted) |
| Density | 1.361±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 3.58±0.10(Predicted) |
| Appearance | White to light yellow Solid |
| CAS DataBase Reference | 143438-91-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2922498590 |
3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC10262 | 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | 143438-91-9 | 1g | $85 | 2026-06-04 | Buy |
| Apolloscientific | PC10262 | 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | 143438-91-9 | 1g | $85 | 2026-06-04 | Buy |
| Activate Scientific | AS34275 | 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | 143438-91-9 | 1g | $43 | 2026-06-04 | Buy |
| Activate Scientific | AS34275 | 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | 143438-91-9 | 5g | $156 | 2026-06-04 | Buy |
| Activate Scientific | AS34275 | 3-Amino-3-[3-(trifluoromethyl)phenyl]propanoic acid 97% | 143438-91-9 | 25g | $526 | 2026-06-04 | Buy |
3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID Chemical Properties,Uses,Production
Synthesis
141-82-2
454-89-7
![3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID](/CAS/GIF/143438-91-9.gif)
143438-91-9
1. malonic acid (298.82 g, 2.872 mol), ammonium formate (362.14 g, 5.743 mol), and 3-(trifluoromethyl)benzaldehyde (500 g, 2.873 mol) were mixed in 1000 mL of ethanol. 2. The mixture was heated and refluxed for 12 h. 3. Upon completion of the reaction, ethanol was removed by evaporation. 4. The residue was milled with 2500 The residue was ground with 2500 mL of acetone. 5. The solid was collected by filtration and dried to give 3-amino-3-[3-(trifluoromethyl)phenyl]propanoic acid (255 g) as a white solid. 6. The product was confirmed by NMR hydrogen spectroscopy (400 MHz, AcOH-d4): δ 7.87-7.81 (m, 2H), 7.74 (d, 1H, J = 7.6 Hz), 7.66- 7.62 (m, 1H), 7.66- 7.62 (m, 1H). 7.62 (m, 1H), 4.98 (br.s, 1H), 3.36 (dd, 1H, J = 16.0, 8.0 Hz), 3.13 (dd, 1H, J = 17.6, 5.6 Hz). 7. Mass spectrometry analysis revealed: m/z 234 (M + 1).
References
[1] Journal of Heterocyclic Chemistry, 2017, vol. 54, # 4, p. 2440 - 2446
[2] Patent: WO2017/144183, 2017, A1. Location in patent: Page/Page column 65
3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID Suppliers
Global( 77)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
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| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
143438-91-9(3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID)Related Search:
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1of4
RARECHEM AK HW 0018
DL-3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID
DL-3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PHENYLPROPIONIC ACID
3-[3-(TRIFLUOROMETHYL)PHENYL]-BETA-ALANINE
3-AMINO-3-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOIC ACID
3-AMINO-3-(3-TRIFLUOROMETHYL-PHENYL)-PROPIONIC ACID
3-TrifluoroMethyl-DL-b-phenylalanine
3-(1-Amino-2-carboxyethyl)benzotrifluoride, 3-Amino-3-[3-(trifluoromethyl)phenyl]propionic acid
DL-3-Amino-3-(3-trifluoromethylphenyl)propanoic acid
(RS)-3-Amino-3-(3-trifluoromethylphenyl)-propionic acid
Benzenepropanoic acid, β-amino-3-(trifluoromethyl)-
(R)-1-(4-chloro-2-fluorophenyl)propan-1-amine
143438-91-9
B-Amino
