PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN
- CAS No.
- 236098-40-1
- Chemical Name:
- PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN
- Synonyms
- [ARG14,LYS15]NOCICEPTIN;[ARG14,LYS15] ORPHANIN FQ;[ARG14, LYS15]NOCICEPTIN/ORPHANIN FQ;PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN;L-Glutamine, L-phenylalanylglycylglycyl-L-phenylalanyl-L-threonylglycyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-arginyl-L-lysyl-L-asparaginyl-
- CBNumber:
- CB2210515
- Molecular Formula:
- C82H137N31O22
- Molecular Weight:
- 1909.16
- MDL Number:
- MFCD03791320
- MOL File:
- 236098-40-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| [Arg14,Lys15]Nociceptin Asreported | 254666 | 1mg | $516 |
| [Arg14,Lys15]Nociceptin | LJA09840 | 5mg | $1428.85 |
| [Arg14,Lys15]Nociceptin | LJA09840 | 10mg | $1987.9 |
| [Arg14,Lys15]Nociceptin | LJA09840 | 25mg | $3727.5 |
| [Arg14,Lys15]Nociceptin | LJA09840 | 50mg | $5963.5 |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 254666 | [Arg14,Lys15]Nociceptin Asreported | 236098-40-1 | 1mg | $516 | 2026-06-03 | Buy |
| Biosynth | LJA09840 | [Arg14,Lys15]Nociceptin | 236098-40-1 | 5mg | $1428.85 | 2026-06-04 | Buy |
| Biosynth | LJA09840 | [Arg14,Lys15]Nociceptin | 236098-40-1 | 10mg | $1987.9 | 2026-06-04 | Buy |
| Biosynth | LJA09840 | [Arg14,Lys15]Nociceptin | 236098-40-1 | 25mg | $3727.5 | 2026-06-04 | Buy |
| Biosynth | LJA09840 | [Arg14,Lys15]Nociceptin | 236098-40-1 | 50mg | $5963.5 | 2026-06-04 | Buy |
PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN Chemical Properties,Uses,Production
Uses
[Arg14,Lys15]Nociceptin is a highly potent and selective NOP receptor (ORL1; OP4) agonist, with an EC50 of 1 nM. [Arg14,Lys15]Nociceptin displays high selectivity over opioid receptors, with IC50s of 0.32, 280, >10000 and 1500 nM for NOP, μ, δ and κ receptors, respectively[1].
in vivo
In in vivo experiments, [Arg14,Lys15]Nociceptin mimics the effects of NC, producing, after intracerebroventricular administration, pronociceptive effects in the tail-withdrawal assay and inhibiting the locomotor activity of the mice[2].
References
[1] Okada K, Sujaku T, Chuman Y, et al. Highly potent nociceptin analog containing the Arg-Lys triple repeat. Biochem Biophys Res Commun. 2000;278(2):493-498. DOI:10.1006/bbrc.2000.3822
[2] Rizzi D, Rizzi A, Bigoni R, et al. [Arg(14),Lys(15)]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: in vitro and in vivo studies. J Pharmacol Exp Ther. 2002;300(1):57-63. DOI:10.1124/jpet.300.1.57
PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN Preparation Products And Raw materials
Raw materials
Preparation Products
PHE-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-ARG-LYS-ASN-GLN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 29660 | 68 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7617 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7189 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 6000 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9835 | 58 |
