ChemicalBook >> CAS DataBase List >>MK-5172
MK-5172
- CAS No.
- 1206524-85-7
- Chemical Name:
- MK-5172
- Synonyms
- MK-5172 intermidiate;MK-5172;EOS-61017;UNII-RU4QU6O6X6;Grazoprevir Impurity 2;Grazoprevir Intermediate 5;(33R,35S,91R,92R,5S)-5-(tert-butyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxylicacid;(1aR,5S,8S,10R,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid;(1aR,5S,8R,10S,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid;(1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
- CBNumber:
- CB22501167
- Molecular Formula:
- C29H38N4O7
- Molecular Weight:
- 554.63
- MDL Number:
- MFCD22741510
- MOL File:
- 1206524-85-7.mol
- MSDS File:
- SDS
Last updated:2026-05-28 00:00:53
| Product description | Number | Pack Size | Price |
| (1R,18R,20R,24S,27S)-24-tert-butyl-7-methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetrazapentacyclo[24.2.1.0{3,12.0{5,10.0{18,20]nonacosa-3,5(10),6,8,11-pentaene-27-carboxylic acid >98% | B66482 | 250mg | $61 |
| (1R,18R,20R,24S,27S)-24-tert-butyl-7-methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetrazapentacyclo[24.2.1.0{3,12.0{5,10.0{18,20]nonacosa-3,5(10),6,8,11-pentaene-27-carboxylic acid >98% | B66482 | 1g | $160 |
| (1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 99% | AA008TAB | 100mg | $30 |
| (1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 98% | AA008TAB | 250mg | $41 |
| (1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 99% | AA008TAB | 1g | $100 |
| More product size | |||
| Melting point | 180-185oC |
|---|---|
| Boiling point | 825.0±65.0 °C(Predicted) |
| Density | 1.33 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol |
| form | Solid |
| pka | 3.23±0.40(Predicted) |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | IVROMYPOGKZNLP-FDOFPDFBSA-N |
| SMILES | N1C2C(=CC=C(OC)C=2)N=C2CCCCC[C@]3([H])C[C@@]3([H])OC(=O)N[C@@H](C(C)(C)C)C(=O)N3C[C@]([H])(OC=12)C[C@H]3C(O)=O |
| FDA UNII | RU4QU6O6X6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| REACH Registrations | Active |
MK-5172 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | B66482 | (1R,18R,20R,24S,27S)-24-tert-butyl-7-methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetrazapentacyclo[24.2.1.0{3,12.0{5,10.0{18,20]nonacosa-3,5(10),6,8,11-pentaene-27-carboxylic acid >98% | 1206524-85-7 | 250mg | $61 | 2026-05-06 | Buy |
| Synthonix | B66482 | (1R,18R,20R,24S,27S)-24-tert-butyl-7-methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetrazapentacyclo[24.2.1.0{3,12.0{5,10.0{18,20]nonacosa-3,5(10),6,8,11-pentaene-27-carboxylic acid >98% | 1206524-85-7 | 1g | $160 | 2026-05-06 | Buy |
| aablocks | AA008TAB | (1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 99% | 1206524-85-7 | 100mg | $30 | 2026-05-28 | Buy |
| aablocks | AA008TAB | (1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 98% | 1206524-85-7 | 250mg | $41 | 2026-05-28 | Buy |
| aablocks | AA008TAB | (1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 99% | 1206524-85-7 | 1g | $100 | 2026-05-28 | Buy |
MK-5172 Chemical Properties,Uses,Production
Uses
MK-5172 is a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants.
Advantages
MK-5172 has a higher barrier to resistance than first-generation protease inhibitors and is active against most variants associated with resistance to first-generation protease inhibitors. Tolerability and safety profile are good.
MK-5172 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 103)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hanhong Scientific Co., Ltd. | +undefined17612118332 | Lucky@hanhonggroup.com | China | 5842 | 58 |
| Adachibio Inc. | +81-8027837258; | sales@adachibio.com | Japan | 938 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1796 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 963 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Shanghai Rochi Pharmaceutical Co.,Ltd. | 21-38751876 +8615000076078 | info@rochipharma.com | China | 504 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15058 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
1206524-85-7(MK-5172)Related Search:
MK-5172
(1aR,5S,8S,10R,22aR)-5-(1,1-Dimethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-methoxy-3,6-dioxo-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
8H-7,10-Methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid, 5-(1,1-diMethylethyl)-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-14-Methoxy-3,6-dioxo-,(1aR,5S,8S,10R,22aR)-
(1aR,5S,8R,10S,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
Grazoprevir Intermediate 5
(33R,35S,91R,92R,5S)-5-(tert-butyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxylicacid
(1aR,5S,8S,10R,22aR)-5-tert-butyl-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
EOS-61017
UNII-RU4QU6O6X6
Grazoprevir Impurity 2
MK-5172 intermidiate
1206524-85-7
C29H38N4O7
intermediates
MK-5172 intermediate
