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TiMolol IMpurity E
- CAS No.
- 1026075-53-5
- Chemical Name:
- TiMolol IMpurity E
- Synonyms
- TiMolol IMpurity E;Timolol EP Impurity E;Timolol Maleate EP Impurity E;Timolol EP Impurity E/ Timolol Related Compound E;Timolol EP Impurity E (Timolol USP Related Compound E (Free Form));(S)-3-(tert-Butylamino)-1-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-yl hydrogen maleate;(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)-amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thia-diazol-3-yl]oxy;(S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid;(Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid;(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5- thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic Acid
- CBNumber:
- CB22675882
- Molecular Formula:
- C17H26N4O6S
- Molecular Weight:
- 414.48
- MDL Number:
- MFCD23160685
- MOL File:
- 1026075-53-5.mol
- MSDS File:
- SDS
Last updated:2026-05-28 00:03:35
| Product description | Number | Pack Size | Price |
| (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | AA01EH4M | 1mg | $60 |
| (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | AA01EH4M | 5mg | $80 |
| (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | AA01EH4M | 10mg | $128 |
| (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | AA01EH4M | 25mg | $256 |
| (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | AA01EH4M | 100mg | $682 |
| Boiling point | 618.1±55.0 °C(Predicted) |
|---|---|
| Density | 1.300±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 2.31±0.25(Predicted) |
| Appearance | White to off-white Solid |
| Major Application | pharmaceutical (small molecule) |
| InChI | 1S/C17H26N4O6S/c1-17(2,3)18-10-12(27-14(24)5-4-13(22)23)11-26-16-15(19-28-20-16)21-6-8-25-9-7-21/h4-5,12,18H,6-11H2,1-3H3,(H,22,23)/b5-4-/t12-/m0/s1 |
| InChIKey | MGIAXRFZDNBKRF-RXNFCKPNSA-N |
| SMILES | [s]1nc(c(n1)OC[C@@H](OC(=O)\C=C/C(=O)O)CNC(C)(C)C)N2CCOCC2 |
| FDA UNII | J2V3WF497E |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
TiMolol IMpurity E price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA01EH4M | (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | 1026075-53-5 | 1mg | $60 | 2026-05-30 | Buy |
| aablocks | AA01EH4M | (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | 1026075-53-5 | 5mg | $80 | 2026-05-30 | Buy |
| aablocks | AA01EH4M | (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | 1026075-53-5 | 10mg | $128 | 2026-05-30 | Buy |
| aablocks | AA01EH4M | (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | 1026075-53-5 | 25mg | $256 | 2026-05-30 | Buy |
| aablocks | AA01EH4M | (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% | 1026075-53-5 | 100mg | $682 | 2026-05-30 | Buy |
TiMolol IMpurity E Chemical Properties,Uses,Production
Uses
1-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl] Ester (2Z)-2-Butenedioic Acid (Timolol EP Impurity E; Timolol BP Impurity E; Timolol USP Related Compound E) is an impurity of Timolol (T4437005), an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.
TiMolol IMpurity E Preparation Products And Raw materials
Raw materials
Preparation Products
TiMolol IMpurity E Suppliers
Global( 48)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14320 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8642 | 58 | |
| sgtlifesciences pvt ltd | +91-8790379245 | dj@sgtlifesciences.com | China | 12351 | 58 |
| Guangzhou Tosun Pharmaceutical Limited | +86-18124244216 +86-18124244216 | info@upharm.cn | China | 995 | 58 |
| Sinco Pharmachem (ShenZhen) R&D Co., Ltd. | +86-18603013401 | jack.lin@sincopharmachem.com | China | 9999 | 58 |
| QUALITY CONTROL SOLUTIONS LTD. | +86-0755-66853366 +8613670046396 | export03@qcsrm.com | China | 24318 | 58 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4484 | 50 | |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | wxf@sungening.com | China | 9609 | 60 |
1026075-53-5(TiMolol IMpurity E)Related Search:
TiMolol IMpurity E
Timolol EP Impurity E
(Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid
Timolol Maleate EP Impurity E
(S)-3-(tert-Butylamino)-1-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-yl hydrogen maleate
2-Butenedioic acid (2Z)-, 1-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl] ester
1-?[(1S)?-?1-?[[(1,?1-?Dimethylethyl)?amino]?methyl]?-?2-?[[4-?(4-?morpholinyl)?-?1,?2,?5-?thiadiazol-?3-?yl]?oxy]?ethyl] Ester (2Z)?-?2-?Butenedioic Acid
DISCONTINUED
Timolol EP Impurity E/ Timolol Related Compound E
(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5- thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic Acid
(S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid (Timolol Impurity)
(S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid
(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)-amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thia-diazol-3-yl]oxy
Timolol EP Impurity E (Timolol USP Related Compound E (Free Form))
1026075-53-5
C17H26N4O6S





