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ChemicalBook >> CAS DataBase List >>TiMolol IMpurity E

TiMolol IMpurity E

CAS No.
1026075-53-5
Chemical Name:
TiMolol IMpurity E
Synonyms
TiMolol IMpurity E;Timolol EP Impurity E;Timolol Maleate EP Impurity E;Timolol EP Impurity E/ Timolol Related Compound E;Timolol EP Impurity E (Timolol USP Related Compound E (Free Form));(S)-3-(tert-Butylamino)-1-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-yl hydrogen maleate;(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)-amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thia-diazol-3-yl]oxy;(S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid;(Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid;(2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5- thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic Acid
CBNumber:
CB22675882
Molecular Formula:
C17H26N4O6S
Molecular Weight:
414.48
MDL Number:
MFCD23160685
MOL File:
1026075-53-5.mol
MSDS File:
SDS
Last updated:2026-05-28 00:03:35
Product description Number Pack Size Price
(S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% AA01EH4M 1mg $60
(S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% AA01EH4M 5mg $80
(S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% AA01EH4M 10mg $128
(S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% AA01EH4M 25mg $256
(S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% AA01EH4M 100mg $682

TiMolol IMpurity E Properties

Boiling point 618.1±55.0 °C(Predicted)
Density 1.300±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 2.31±0.25(Predicted)
Appearance White to off-white Solid
Major Application pharmaceutical (small molecule)
InChI 1S/C17H26N4O6S/c1-17(2,3)18-10-12(27-14(24)5-4-13(22)23)11-26-16-15(19-28-20-16)21-6-8-25-9-7-21/h4-5,12,18H,6-11H2,1-3H3,(H,22,23)/b5-4-/t12-/m0/s1
InChIKey MGIAXRFZDNBKRF-RXNFCKPNSA-N
SMILES [s]1nc(c(n1)OC[C@@H](OC(=O)\C=C/C(=O)O)CNC(C)(C)C)N2CCOCC2
FDA UNII J2V3WF497E
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral

TiMolol IMpurity E price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA01EH4M (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% 1026075-53-5 1mg $60 2026-05-30 Buy
aablocks AA01EH4M (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% 1026075-53-5 5mg $80 2026-05-30 Buy
aablocks AA01EH4M (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% 1026075-53-5 10mg $128 2026-05-30 Buy
aablocks AA01EH4M (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% 1026075-53-5 25mg $256 2026-05-30 Buy
aablocks AA01EH4M (S, Z)-4-((1-(tert-butylamino)-3-((4-morpholino-1, 2, 5- thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid 98% 1026075-53-5 100mg $682 2026-05-30 Buy
Product number Packaging Price Buy
AA01EH4M 1mg $60 Buy
AA01EH4M 5mg $80 Buy
AA01EH4M 10mg $128 Buy
AA01EH4M 25mg $256 Buy
AA01EH4M 100mg $682 Buy

TiMolol IMpurity E Chemical Properties,Uses,Production

Uses

1-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl] Ester (2Z)-2-Butenedioic Acid (Timolol EP Impurity E; Timolol BP Impurity E; Timolol USP Related Compound E) is an impurity of Timolol (T4437005), an adrenergic blocking agent (1); antiarrhythmic (class II); antianginal; antiglaucoma (2) and antihypertensive (3) agent.

TiMolol IMpurity E Preparation Products And Raw materials

Raw materials

Preparation Products

TiMolol IMpurity E Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14320 58
BOC Sciences
16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
CR Corporation Limited
fred.wen@crcorporation.cn China 8642 58
sgtlifesciences pvt ltd
+91-8790379245 dj@sgtlifesciences.com China 12351 58
Guangzhou Tosun Pharmaceutical Limited
+86-18124244216 +86-18124244216 info@upharm.cn China 995 58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.
+86-18603013401 jack.lin@sincopharmachem.com China 9999 58
QUALITY CONTROL SOLUTIONS LTD.
+86-0755-66853366 +8613670046396 export03@qcsrm.com China 24318 58
S.Z. PhyStandard Bio-Tech. Co., Ltd. 0755-83725681-603 China 4484 50
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9609 60

TiMolol IMpurity E Spectrum

TiMolol IMpurity E Timolol EP Impurity E (Z)-4-[(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl]oxy-4-oxobut-2-enoic acid Timolol Maleate EP Impurity E (S)-3-(tert-Butylamino)-1-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-yl hydrogen maleate 2-Butenedioic acid (2Z)-, 1-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl] ester 1-?[(1S)?-?1-?[[(1,?1-?Dimethylethyl)?amino]?methyl]?-?2-?[[4-?(4-?morpholinyl)?-?1,?2,?5-?thiadiazol-?3-?yl]?oxy]?ethyl] Ester (2Z)?-?2-?Butenedioic Acid DISCONTINUED Timolol EP Impurity E/ Timolol Related Compound E (2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5- thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic Acid (S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid (Timolol Impurity) (S,Z)-4-((1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-yl)oxy)-4-oxobut-2-enoic acid (2Z)-4-[(1S)-1-[[(1,1-Dimethylethyl)-amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thia-diazol-3-yl]oxy Timolol EP Impurity E (Timolol USP Related Compound E (Free Form)) 1026075-53-5 C17H26N4O6S
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