Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride
![Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride Structure](CAS/20180629/GIF/1038866-44-2.gif)
- CAS No.
- 1038866-44-2
- Chemical Name:
- Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride
- Synonyms
- -one hydrochloride;Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H);Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride
- CBNumber:
- CB22748803
- Molecular Formula:
- C11H14ClN3O2
- Molecular Weight:
- 255.70076
- MDL Number:
- MFCD21608029
- MOL File:
- 1038866-44-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | S55457 | 100mg | $90 |
| Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | S55457 | 250mg | $130 |
| Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | S55457 | 1g | $290 |
| Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | S55457 | 5g | $1450 |
| Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | AA0095TU | 250mg | $46 |
Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | S55457 | Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | 1038866-44-2 | 100mg | $90 | 2026-05-06 | Buy |
| Synthonix | S55457 | Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | 1038866-44-2 | 250mg | $130 | 2026-05-06 | Buy |
| Synthonix | S55457 | Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | 1038866-44-2 | 1g | $290 | 2026-05-06 | Buy |
| Synthonix | S55457 | Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | 1038866-44-2 | 5g | $1450 | 2026-05-06 | Buy |
| aablocks | AA0095TU | Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride 97% | 1038866-44-2 | 250mg | $46 | 2026-05-28 | Buy |
Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride Chemical Properties,Uses,Production
Synthesis
![Benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxylate](/CAS/20150408/GIF/883984-95-0.gif)
883984-95-0
![Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride](/CAS/20180629/GIF/1038866-44-2.gif)
1038866-44-2
Step 3: 16.4 g (42.4 mmol) of benzyl 7'-chloro-2'-oxo-1',2'-dihydrospiro[piperidin-4,4'-pyrido[2,3-d][1,3]oxazine]-1 -carboxylate and 2.00 g of 10% palladium/carbon (Pd/C) catalyst were placed in 500 mL of ethanol and hydrogenated at room temperature under a hydrogen atmosphere for 6 hours. Subsequently, 1.0 g of 10% palladium/carbon (Pd/C) catalyst was added additionally and the hydrogenation was continued for 3 hours at room temperature under hydrogen atmosphere. Upon completion of the reaction, the reaction mixture was filtered and the solvent was removed under vacuum. The resulting residue was ground with ethanol and the resulting precipitate was collected by diafiltration, washed with ethanol and dried. A final product of 5.40 g was obtained in a yield of 50% of the theoretical value. The product was analyzed by ESI-MS showing m/z = 220 (M + H)+ and HPLC retention time (Rt) of 0.90 min (Method C).
References
[1] Patent: US2011/21500, 2011, A1. Location in patent: Page/Page column 46
[2] Patent: US2012/149698, 2012, A1. Location in patent: Page/Page column 26
Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Spiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazin]-2'(1'H)-one hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
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| Nanjing Moldeep Biochemical Co., Ltd. | +86-25-58282389 +86-17351037455 | inquiries@moldeep.com | China | 20000 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. | 02161555100 | China | 820 | 58 | |
| TaiChem Taizhou Limited | 052386810091 | zcwy9518@yeah.net | China | 3918 | 58 |
| Taian Jiaye Biotechnology Co.Ltd | 15318151873;13127280945 | 285424065@qq.com | China | 9976 | 55 |
| Shanghai Baozhi Biological Technology Co., Ltd. | 13764058804 | 3438424070@qq.com | China | 380 | 58 |
| Aikon International Limited | 025-58851090 13913916777 | sales01@aikonchem.com | China | 15949 | 58 |
