ChemicalBook >> CAS DataBase List >>M2I-1
M2I-1
- CAS No.
- 312271-03-7
- Chemical Name:
- M2I-1
- Synonyms
- M2I-1;M2I1;M2I 1;M2I-1;Mad2 inhibitor-1;M2I-1, 10 mM in DMSO;Mad2 inhibitor-1 (M2I-1);PPI,M2I-1,M2I1,inhibit,M-2I-1,interaction,protein-protein,Cdc20,Inhibitor,Mad2;5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione;4,6(1H,5H)-Pyrimidinedione, 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylene]dihydro-2-thioxo-
- CBNumber:
- CB23128969
- Molecular Formula:
- C19H24N4O4S
- Molecular Weight:
- 404.48
- MDL Number:
- MFCD00469459
- MOL File:
- 312271-03-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-22 18:57:36
| Product description | Number | Pack Size | Price |
| M2I-1 ≥98% | 22297 | 1mg | $36 |
| M2I-1 ≥98% | 22297 | 5mg | $77 |
| M2I-1 ≥98% | 22297 | 10mg | $120 |
| M2I-1 ≥98% | 22297 | 25mg | $253 |
| M2I-1 ≥98% | 22297 | 1mg | $32 |
| More product size | |||
M2I-1 price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 5mg | $77 | 2026-04-30 | Buy |
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 10mg | $120 | 2026-04-30 | Buy |
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 25mg | $253 | 2026-04-30 | Buy |
| Cayman Chemical | 22297 | M2I-1 ≥98% | 312271-03-7 | 1mg | $32 | 2024-03-01 | Buy |
M2I-1 Chemical Properties,Uses,Production
Uses
M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC)[1].
Biological Activity
Cell permeable: yes', 'Primary Target
Mad2', 'Reversible: yes
References
[1] Johanna Kastl et al. Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem. Biol., 2015, 10 (7), pp 1661-1666. DOI:10.1021/acschembio.5b00121
M2I-1 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 86)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11680 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9945 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
M2I-1
5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
M2I1;M2I 1;M2I-1
Mad2 inhibitor-1 (M2I-1)
Mad2 inhibitor-1
4,6(1H,5H)-Pyrimidinedione, 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylene]dihydro-2-thioxo-
PPI,M2I-1,M2I1,inhibit,M-2I-1,interaction,protein-protein,Cdc20,Inhibitor,Mad2
M2I-1, 10 mM in DMSO
312271-03-7
API
