ChemicalBook >> CAS DataBase List >>(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate
(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate
- CAS No.
- 1448440-50-3
- Chemical Name:
- (S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate
- Synonyms
- tert-butyl (S)-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate;133998;(S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carbonitrile;(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate;1,1-Dimethylethyl N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]carbamate;Carbamic acid, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-, 1,1-dimethylethyl ester
- CBNumber:
- CB23150836
- Molecular Formula:
- C12H17F2N3O3
- Molecular Weight:
- 289.28
- MDL Number:
- MFCD29049850
- MOL File:
- 1448440-50-3.mol
- MSDS File:
- SDS
Last updated:2026-05-28 00:08:27
| Product description | Number | Pack Size | Price |
| (S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate | 153692 | 1.00g | $79 |
| (S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate | 153692 | 5.00g | $235 |
| (S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate | 153692 | 10.00g | $389 |
| (S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carbonitrile ≥97% | A74054 | 250mg | $41 |
| (S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carbonitrile ≥97% | A74054 | 1g | $90 |
| Boiling point | 465.4±45.0 °C(Predicted) |
|---|---|
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Store at room temperature |
| pka | 11.55±0.46(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C12H17F2N3O3/c1-11(2,3)20-10(19)16-6-9(18)17-7-12(13,14)4-8(17)5-15/h8H,4,6-7H2,1-3H3,(H,16,19)/t8-/m0/s1 |
| InChIKey | WOOAQTYGIARQIQ-QMMMGPOBSA-N |
| SMILES | C(OC(C)(C)C)(=O)NCC(N1CC(F)(F)C[C@H]1C#N)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 153692 | (S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate | 1448440-50-3 | 1.00g | $79 | 2026-05-18 | Buy |
| Matrix Scientific | 153692 | (S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate | 1448440-50-3 | 5.00g | $235 | 2026-05-18 | Buy |
| Matrix Scientific | 153692 | (S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate | 1448440-50-3 | 10.00g | $389 | 2026-05-18 | Buy |
| Synthonix | A74054 | (S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carbonitrile ≥97% | 1448440-50-3 | 250mg | $41 | 2026-05-06 | Buy |
| Synthonix | A74054 | (S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carbonitrile ≥97% | 1448440-50-3 | 1g | $90 | 2026-05-06 | Buy |
(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate Chemical Properties,Uses,Production
Uses
(S)-tert-Butyl (2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate is an intermediate in the synthesis of (S)-N-(2-(2-Cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)quinoline-4-carboxamide (UAMC1110) (S687910) which is a useful research chemical and a fibroblast activation protein inhibitor displaying low nanomolar inhibitory potency and high selectivity against related dipeptidyl peptidases.
Synthesis of (S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate from BOC-Glycine and (S)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride
(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate Preparation Products And Raw materials
(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate Suppliers
Global( 31)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Shanghai Joy Biotech Ltd. | +86-15968534750 +86-1358845959750 | sales@joybiotech.com | China | 1001 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10973 | 64 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4540 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4865 | 55 | |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4975 | 55 |
| BioPharmaMatrix,Inc. | 0510-86010668 | sales@biopharmamatrix.com | China | 4926 | 55 |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 3927209986@qq.com | China | 9980 | 55 |
| Wuxi KaideRui Pharmaceutical Technology Co., Ltd | 19906241957 | 1557216087@qq.com | China | 1853 | 55 |
1448440-50-3((S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate)Related Search:
(S)-1-(2-aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride
2-Pyrrolidinecarbonitrile, 1-(2-aminoacetyl)-4,4-difluoro-
2-Pyrrolidinecarbonitrile, 1-(2-aminoacetyl)-4,4-difluoro-, (2R)-
(S)-1-(2-aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile
2-Pyrrolidinecarbonitrile, 1-(2-aminoacetyl)-4,4-difluoro-, hydrochloride (1:1)
1of2
(S)-tert-butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate
133998
(S)-1-[2-(Boc-amino)acetyl]-4,4-difluoropyrrolidine-2-carbonitrile
Carbamic acid, N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]-, 1,1-dimethylethyl ester
1,1-Dimethylethyl N-[2-[(2S)-2-cyano-4,4-difluoro-1-pyrrolidinyl]-2-oxoethyl]carbamate
tert-butyl (S)-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate
1448440-50-3
C12H17F2N3O3
