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ChemicalBook >> CAS DataBase List >>NOC-5

NOC-5

CAS No.
146724-82-5
Chemical Name:
NOC-5
Synonyms
NOC 5;NOC-5;NOC 5,NOC5;3-(aminopropyl)-1-hydr;3-(aminopropyl)-1-hydroxy-3-isopropyl-*2-oxo-1-tr;3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2- OXO-1-TRIA;3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2-OXO-1-TRIAZENE;1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-ISOPROPYL-1-TRIAZENE;3-(2-Hydroxy-1-isopropyl-2-nitrosohydrazino)-propylamine;N-[3-aminopropyl(propan-2-yl)amino]-N-hydroxynitrous amide
CBNumber:
CB2477303
Molecular Formula:
C6H16N4O2
Molecular Weight:
176.22
MDL Number:
MFCD00274389
MOL File:
146724-82-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:43:01
Product description Number Pack Size Price
NOC-5 ≥95% A5456 10mg $286
NOC-5 - CAS 146724-82-5 - Calbiochem A nitric oxide (NO) donor. 487950 10MG $179
NOC-5 ≥98% 16534 1mg $49
NOC-5 ≥98% 16534 5mg $107
NOC-5 ≥98% 16534 10mg $190
More product size

NOC-5 Properties

storage temp. -20°C
solubility Water
form White solid
color White
Water Solubility 0.1 M NaOH: soluble
water: soluble
Stability Store at -20°C, Light and Moisture Sensitive
InChI 1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,11H,3-5,7H2,1-2H3/b10-8-
InChIKey MTIRIKBRVALRPJ-NTMALXAHSA-N
SMILES CC(C)N(CCCN)\[N+]([O-])=N\O
UNSPSC Code 12352204
NACRES NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)
GHS02
Signal word  Danger
Hazard statements  H242
Precautionary statements  P210-P234-P235-P240-P370+P378-P403
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Storage Class 5.2 - Organic peroxides and self-reacting hazardous materials
Hazard Classifications Self-react. C
NFPA 704
0
2 0

NOC-5 price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A5456 NOC-5 ≥95% 146724-82-5 10mg $286 2026-04-30 Buy
Sigma-Aldrich 487950 NOC-5 - CAS 146724-82-5 - Calbiochem A nitric oxide (NO) donor. 146724-82-5 10MG $179 2022-05-15 Buy
Cayman Chemical 16534 NOC-5 ≥98% 146724-82-5 1mg $49 2026-04-30 Buy
Cayman Chemical 16534 NOC-5 ≥98% 146724-82-5 5mg $107 2026-04-30 Buy
Cayman Chemical 16534 NOC-5 ≥98% 146724-82-5 10mg $190 2026-04-30 Buy
Product number Packaging Price Buy
A5456 10mg $286 Buy
487950 10MG $179 Buy
16534 1mg $49 Buy
16534 5mg $107 Buy
16534 10mg $190 Buy

NOC-5 Chemical Properties,Uses,Production

Description

NOC-5 is a stable nitric oxide (NO)-amine complex that acts as a NO donor. It can release two equivalents of NO in solution under physiological conditions without a cofactor. The half-life of NOC-5 in PBS (pH 7.4) is 93 minutes at 22°C, and it remains relatively stable in alkaline solution (pH ≥10.0).

Chemical Properties

White Powder

Uses

Releases nitric oxide spontaneously in a rate-controlled manner; half life in solution = 93 min.

Uses

A stable NO-amine complex which can release NO spontaneously under physiological conditions. The half life of NO release in 0.1 M PBS at (pH7.4) at 37C for 0.1mM NOC 5 is 25 minutes.

Definition

ChEBI: NOC-5 is a nitroso compound that is triazane in which the nitrogen at position 1 is substituted by an isopropyl group and a 3-aminopropyl group, that at position 2 is substituted by a hydroxy group, and that at position 3 is substituted by an oxo group. It is a nitric oxide donor. It has a role as a nitric oxide donor. It is a nitroso compound, a tertiary amino compound and a primary amino compound.

References

[1] JOSEPH A. HRABIE. New nitric oxide-releasing zwitterions derived from polyamines[J]. The Journal of Organic Chemistry, 1993, 58 6: 1472-1476. DOI: 10.1021/jo00058a030

NOC-5 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 69)Suppliers
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3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15838 69
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9658 60
Shanghai Macklin Biochemical Co.,Ltd. 15221275939 15221275939 shenlinxing@macklin.cn China 15781 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9804 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 45000 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29757 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24959 58
Shanghai Yingxin laboratory equipment Co., Ltd 021-021-59178156 15300768757 359382369@qq.com China 10674 58
NOC-5 3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2-OXO-1-TRIAZENE 1-HYDROXY-2-OXO-3-(3-AMINOPROPYL)-3-ISOPROPYL-1-TRIAZENE 3-(aminopropyl)-1-hydr 3-[2-Hydroxy-1-(1-Methylethyl)-2-Nitrosohydrazino]-1-Propanamine Discontinued 3-[2-HYDROXY-1-(1-METHYLETHYL)-2-NITROSOHYDRAZINO]-1-PROPANAMINE NOC 5 3-(aminopropyl)-1-hydroxy-3-isopropyl-*2-oxo-1-tr 3-(AMINOPROPYL)-1-HYDROXY-3-ISOPROPYL-2- OXO-1-TRIA 3-(2-Hydroxy-1-isopropyl-2-nitrosohydrazino)-propylamine N-[3-aminopropyl(propan-2-yl)amino]-N-hydroxynitrous amide 1-Propanamine, 3-[2-hydroxy-1-(1-methylethyl)-2-nitrosohydrazinyl]- NOC 5,NOC5 146724-82-5 Cell Signaling Enzymes Biochemicals and Reagents Application Index BioChemical Enzymes, Inhibitors, and Substrates Nitric Oxide Metabolism NO Donors Nitric Oxide Reagents
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