3,6-DIOXAOCTANEDIOIC ACID
- CAS No.
- 23243-68-7
- Chemical Name:
- 3,6-DIOXAOCTANEDIOIC ACID
- Synonyms
- 2,2'-(Ethane-1,2-diylbis(oxy))diacetic acid;DOODA;PEG2-(CH2CO2H)2;3,6-Dioxasuberic acid;HOOCCH2O-PEG1-CH2COOH;3, 6-dioxyoctaneic acid;3,6-dioxoctanedioic acid;3,6-Dioxaoctandioic acid;3,6-DIOXAOCTANEDIOIC ACID;(Ethylenebisoxy)diacetic acid
- CBNumber:
- CB2499237
- Molecular Formula:
- C6H10O6
- Molecular Weight:
- 178.14
- MDL Number:
- MFCD00054502
- MOL File:
- 23243-68-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (2-CARBOXYMETHOXYETHOXY)ACETIC ACID 97% | 59606 | 1G | $44 |
| (2-CARBOXYMETHOXYETHOXY)ACETIC ACID 97% | 59606 | 5G | $134 |
| 3,6-Dioxaoctanedioic acid | FD154915 | 5g | $900 |
| 3,6-Dioxaoctanedioic acid | FD154915 | 2g | $900 |
| 3,6-Dioxaoctanedioic acid | FD154915 | 1g | $900 |
| More product size | |||
| Melting point | 68-71℃ |
|---|---|
| Boiling point | 429.2±25.0 °C(Predicted) |
| Density | 1.375 |
| vapor pressure | 0Pa at 20℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 3.09±0.10(Predicted) |
| form | solid |
| color | White to off-white |
| InChI | InChI=1S/C6H10O6/c7-5(8)3-11-1-2-12-4-6(9)10/h1-4H2,(H,7,8)(H,9,10) |
| InChIKey | CQWXKASOCUAEOW-UHFFFAOYSA-N |
| SMILES | C(OCC(O)=O)COCC(O)=O |
| LogP | -2.29 at 25℃ |
| FDA UNII | 2ZVS8WS40O |
| UNSPSC Code | 12352301 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P312 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45-27-22 |
| RIDADR | 3261 |
| WGK Germany | WGK 1 |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 2917198090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Dam. 1 |
| REACH Registrations | Inactive |
3,6-DIOXAOCTANEDIOIC ACID price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 59606 | (2-CARBOXYMETHOXYETHOXY)ACETIC ACID 97% | 23243-68-7 | 1G | $44 | 2026-04-30 | Buy |
| AstaTech | 59606 | (2-CARBOXYMETHOXYETHOXY)ACETIC ACID 97% | 23243-68-7 | 5G | $134 | 2026-04-30 | Buy |
| Biosynth | FD154915 | 3,6-Dioxaoctanedioic acid | 23243-68-7 | 5g | $900 | 2026-06-04 | Buy |
| Biosynth | FD154915 | 3,6-Dioxaoctanedioic acid | 23243-68-7 | 2g | $900 | 2026-06-04 | Buy |
| Biosynth | FD154915 | 3,6-Dioxaoctanedioic acid | 23243-68-7 | 1g | $900 | 2026-06-04 | Buy |
3,6-DIOXAOCTANEDIOIC ACID Chemical Properties,Uses,Production
Uses
3,6-Dioxaoctanedioic Acid (cas# 23243-68-7) is a useful research chemical.
Description
PEG2-(CH2CO2H)2 is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
3,6-Dioxaoctanedioic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Uses
3,6-Dioxaoctanedioic Acid is a useful reagent for the preparation of degradation agents for cyclin dependent kinase.
Flammability and Explosibility
Not classified
Synthesis
To 15 ml (0.33 mol) of nitric acid was added at 45C while stirring 1 g of diethylene glycol from the overall amount of 5.9 g (0.06 mol), and the mixture was heated to 65C. After the end of nitrogen oxides evolution and cooling the mixture to 45-50C another portion of diethylene glycol was added. Overall time of the reagent addition to the reaction mixture was 1 h. The mixture was kept at 45C for 40 min and then it was heated at 80C for 30 min. The solvent was removed in a vacuum at 70C, the residue was dried by azeotropic distillation with benzene using Dean-Stark trap, then the product was fi ltered off and recrystallized from acetone-benzene mixture. 3,6-Dioxaoctanedioic acid (VIII) was similarly obtained. Yield 7.3 g (89%), colorless crystals. Rf 0.20 (E), mp 76-77C (mp 75-76C [13]). IR spectrum, |í, cm-1: 3167 (OH), 2914 (CH), 1733 (C=O acid), 1410, 1229 (C-O), 1121 (C-O). Mass spectrum, m/z (Irel, %): 178.5 [M]+ (76), 200.9 (55), 216.8 (46).
IC 50
PEGs
References
[1] Patent: CN105669707, 2016, A. Location in patent: Paragraph 0018; 0019
3,6-DIOXAOCTANEDIOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 | sales@rlavie.com | China | 1030 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8834 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
View Lastest Price from 3,6-DIOXAOCTANEDIOIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-24 | 3,6-Dioxaoctanedioic acid
23243-68-7
|
$48.00-172.00 | 5g | 0.98 | 25kg | Shanghai UCHEM Inc. | |
 |
2025-07-02 | 3,6-DIOXAOCTANEDIOIC ACID
23243-68-7
|
1KG | 98% | 1000KG /month | Shanghai Daken Advanced Materials Co.,Ltd | ||
 |
2022-09-01 | 3, 6-dioxyoctaneic acid
23243-68-7
|
10g | 95% | 10kg | Zhengzhou Gecko Scientific Inc. |
-
- 3,6-Dioxaoctanedioic acid
23243-68-7
- $48.00-172.00
- 0.98
- Shanghai UCHEM Inc.
-
- 3,6-DIOXAOCTANEDIOIC ACID
23243-68-7
- $0.00
- 98%
- Shanghai Daken Advanced Materials Co.,Ltd
-
- 3, 6-dioxyoctaneic acid
23243-68-7
- 95%
- Zhengzhou Gecko Scientific Inc.
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