Methyl 3-amino-4-phenylthiophene-2-carboxylate
- CAS No.
- 82437-64-7
- Chemical Name:
- Methyl 3-amino-4-phenylthiophene-2-carboxylate
- Synonyms
- Methyl 3-amino-4-phenylthiophene-2-carboxylate;Methyl 3-amino-4-phenylthiophene-2-carboxylate ,98%;3-Amino-4-phenyl-2-thiophenecarboxylic acid methyl ester;2-Thiophenecarboxylic acid, 3-amino-4-phenyl-, methyl ester;JR-8062, Methyl 3-amino-4-phenylthiophene-2-carboxylate, 97%
- CBNumber:
- CB2501682
- Molecular Formula:
- C12H11NO2S
- Molecular Weight:
- 233.29
- MDL Number:
- MFCD00206450
- MOL File:
- 82437-64-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 3-amino-4-phenylthiophene-2-carboxylate Aldrich | JRD0490 | 1g | $197 |
| Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | M55674 | 100mg | $552 |
| Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | M55674 | 5g | $590 |
| Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | M55674 | 250mg | $698 |
| Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | M55674 | 1g | $810 |
| Melting point | 69 °C |
|---|---|
| Density | 1.265 |
| storage temp. | 2-8°C(protect from light) |
| form | solid |
| InChI | InChI=1S/C12H11NO2S/c1-15-12(14)11-10(13)9(7-16-11)8-5-3-2-4-6-8/h2-7H,13H2,1H3 |
| InChIKey | UKWKMKNACSKDCN-UHFFFAOYSA-N |
| SMILES | C1(C(OC)=O)SC=C(C2=CC=CC=C2)C=1N |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
Methyl 3-amino-4-phenylthiophene-2-carboxylate price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | JRD0490 | Methyl 3-amino-4-phenylthiophene-2-carboxylate Aldrich | 82437-64-7 | 1g | $197 | 2026-04-30 | Buy |
| Synthonix | M55674 | Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | 82437-64-7 | 100mg | $552 | 2026-05-06 | Buy |
| Synthonix | M55674 | Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | 82437-64-7 | 5g | $590 | 2026-05-06 | Buy |
| Synthonix | M55674 | Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | 82437-64-7 | 250mg | $698 | 2026-05-06 | Buy |
| Synthonix | M55674 | Methyl 3-amino-4-phenylthiophene-2-carboxylate 95+% | 82437-64-7 | 1g | $810 | 2026-05-06 | Buy |
Methyl 3-amino-4-phenylthiophene-2-carboxylate Chemical Properties,Uses,Production
Chemical Properties
Light yellow solid
Synthesis
73591-08-9
2365-48-2
82437-64-7
GENERAL STEPS: Sodium methanolate (5 M methanol solution, 3.5 mL, 17.6 mmol) and methyl mercaptoacetate (1.8 mL, 20.1 mmol) were added sequentially to 3-methoxy-2-phenylacrylonitrile (2 g, 12.6 mmol). The reaction mixture was stirred and refluxed at 65 °C overnight. After completion of the reaction, the mixture was filtered using diatomaceous earth and the filter cake was washed with dichloromethane. The crude product was purified by column chromatography (silica gel, n-hexane: ethyl acetate = 5:1) to afford the white solid product methyl 3-amino-4-phenylthiophene-2-carboxylate (1.5 g, 6.6 mmol, 52% yield in two steps). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 7.49-7.39 (m, 5H), 7.25 (s, 1H), 5.64 (br, 2H), 3.88 (s, 3H).
References
[1] Bulletin of the Korean Chemical Society, 2015, vol. 36, # 5, p. 1439 - 1451
[2] Patent: US2014/228565, 2014, A1. Location in patent: Paragraph 0197; 0198
[3] European Journal of Medicinal Chemistry, 2014, vol. 85, p. 629 - 637
Methyl 3-amino-4-phenylthiophene-2-carboxylate Preparation Products And Raw materials
Methyl 3-amino-4-phenylthiophene-2-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11598 | 64 |
| Changzhou Extraordinary Pharmatech co., LTD. | 0519-82111935 15195055733 | info@feifanchem.com | China | 633 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4378 | 65 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9756 | 58 |
