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SCD1 (M38) Antibody

CAS No.
Chemical Name:
SCD1 (M38) Antibody
Synonyms
SCD1 (M38) Antibody
CBNumber:
CB25530548
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

SCD1 (M38) Antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse

Background

Stearoyl-CoA desaturase 1 is a key lipogenic enzyme found in the endoplasmic reticulum that catalyzes the conversion of palmitoyl–CoA and stearoyl–CoA to palmitoleoyl–CoA and oleoyl–CoA. Palmitoleate and oleate are the major components of triglycerides, membrane phospholipids, and cholesterol esters. SCD1-knockout mice show improved insulin sensitivity and reduced body fat. Disruption of SCD1 in mouse brown adipose tissue strengthens insulin signaling and results in increased translocation of Glut4 to the plasma membrane and enhanced uptake of glucose. Furthermore, SCD1 is essential for the onset of diet-induced body weight gain and insulin resistance in the liver.

References

[1] Ntambi, J.M. et al. (2002) Proc. Natl. Acad. Sci. USA 99, 11482-114866.
[2] Kato, H. et al. (2006) J. Cell. Sci. 119, 2342-2353.
[3] Ozols, J. (1997) Mol. Biol. Cell 8, 2281-2290.
[4] Rahman, S.M. et al. (2005) Am. J Physiol. Endocrinol. Metab. 288, E381-387.
[5] Gutiérrez-Juárez, R. et al. (2006) J. Clin. Invest. 116, 1686-1695.

SCD1 (M38) Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

SCD1 (M38) Antibody Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25021 58
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Hangzhou Novas Biotechnology Co., Ltd. 15264006066 CHINA 1844 58
Beijing Boning Biotechnology Co., Ltd. 010-67500625 18210120938 384669408@qq.com China 6395 58
SCD1 (M38) Antibody
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