一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

MKK3b Antibody

CAS No.
Chemical Name:
MKK3b Antibody
Synonyms
MKK3b Antibody
CBNumber:
CB25741814
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

MKK3b Antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat

Background

MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase. MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAPK/JNK. Phosphorylation of p38 MAP kinase dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines. Activation of MKK3 and MKK6 occurs through phosphorylation at Ser189 and Thr222 on MKK3 and Ser207 and Thr211 on MKK6.Three alternatively spliced transcript variants of MKK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MKK3b is the predominant form of MKK3 and strongly activates p38 MAP kinase.

References

[1] Derijard, B. et al. (1995) Science 267, 682-685.
[2] Raingeaud, J. et al. (1995) J. Biol. Chem. 270, 7420-7426.
[3] Sluss, H.K. et al. (1994) Mol. Cell. Biol. 14, 8376-8384.
[4] Raingeaud, J. et al. (1996) Mol. Cell. Biol. 16(3), 1247-1255.
[5] Han, J. et al. (1996) J. Biol. Chem. 271, 2886-2891.
[6] Han, J. et al. (1997) FEBS Letters 403(1) , 19-22.

MKK3b Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

MKK3b Antibody Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Supplier Advantage
Cell Signaling Technology Inc 58
MKK3b Antibody
怀仁县| 晋城| 平度市| 聊城市| 庄浪县| 慈溪市| 井研县| 大关县| 深泽县| 申扎县| 荆州市| 郁南县| 赤峰市| 双柏县| 新乡市| 德化县| 大港区| 东方市| 舒兰市| 桂阳县| 沛县| 黔西| 鄂伦春自治旗| 罗源县| 亚东县| 泰来县| 都江堰市| 彭泽县| 突泉县| 平和县| 团风县| 唐海县| 普洱| 吉木乃县| 扬中市| 南京市| 前郭尔| 蕉岭县| 洛阳市| 二连浩特市| 施秉县|