2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE
- CAS No.
- 316173-57-6
- Chemical Name:
- 2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE
- Synonyms
- SCH 442416;SCH-442417;SCH442416, 10 mM in DMSO;A2A,SCH442416,imaging,inhibit,P1 receptor,Inhibitor,Adenosine Receptor,adenosine,SCH-442416;2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo-[4,3-e][1,2,4]triazolo[1,5-c]pyrimidi;5-Amino-7-(3-(4-methoxyphenyl)propyl)-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine;2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo-[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5;2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE;2-(Furan-2-yl)-7-(3-(4-methoxyphenyl)propyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine,2-(2-furanyl)-7-[3-(4-methoxyphenyl)propyl]-
- CBNumber:
- CB2850687
- Molecular Formula:
- C20H19N7O2
- Molecular Weight:
- 389.41
- MDL Number:
- MFCD08703126
- MOL File:
- 316173-57-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| SCH-442416 ≥98% (HPLC) | S6451 | 5mg | $112 |
| SCH-442416 ≥98% (HPLC) | S6451 | 25mg | $445 |
| SCH 442416 ≥98% | 22233 | 1mg | $36 |
| SCH 442416 ≥98% | 22233 | 5mg | $145 |
| SCH 442416 ≥98% | 22233 | 10mg | $236 |
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Properties
| Density | 1.49±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | 2-8°C |
| solubility | DMSO: ≥20mg/mL |
| pka | 2.77±0.30(Predicted) |
| form | powder |
| color | light tan to tan |
| InChI | 1S/C20H19N7O2/c1-28-14-8-6-13(7-9-14)4-2-10-26-18-15(12-22-26)19-23-17(16-5-3-11-29-16)25-27(19)20(21)24-18/h3,5-9,11-12H,2,4,10H2,1H3,(H2,21,24) |
| InChIKey | AEULVFLPCJOBCE-UHFFFAOYSA-N |
| SMILES | COc1ccc(CCCn2ncc3c2nc(N)n4nc(nc34)-c5ccco5)cc1 |
| FDA UNII | ZMC4G1W59S |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE price More Price(79)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S6451 | SCH-442416 ≥98% (HPLC) | 316173-57-6 | 5mg | $112 | 2026-04-30 | Buy |
| Sigma-Aldrich | S6451 | SCH-442416 ≥98% (HPLC) | 316173-57-6 | 25mg | $445 | 2026-04-30 | Buy |
| Cayman Chemical | 22233 | SCH 442416 ≥98% | 316173-57-6 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 22233 | SCH 442416 ≥98% | 316173-57-6 | 5mg | $145 | 2026-04-30 | Buy |
| Cayman Chemical | 22233 | SCH 442416 ≥98% | 316173-57-6 | 10mg | $236 | 2026-04-30 | Buy |
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Chemical Properties,Uses,Production
Uses
SCH 442416 is a potent and selective A2A adenosine receptor antagonist.
Definition
ChEBI: LSM-3027 is a member of triazolopyrimidines.
Biological Activity
Extremely selective adenosine A 2A receptor antagonist that binds to human and rat A 2A receptors with high affinity (K i values are 0.048 and 0.5 nM respectively). In vitro displays > 23000-fold selectivity for hA 2A over hA 1 and minimal affinity for hA 2B and hA 3 receptors (IC 50 > 10 μ M).
Biochem/physiol Actions
SCH-442416 potent and selective Adenosine A2a antagonist. SCH-442416 is >10,000-fold selective for A2a compared to other adensosine receptors.
storage
Store at RT
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Chengdu NoVi Biotechnology Co., Ltd. | 028-81458053 | novibiotech@163.com sales@novi-biotech.com | China | 226 | 55 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4785 | 55 |
| LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
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2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE Spectrum
316173-57-6(2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE)Related Search:
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