5-Isoquinolinamine,3-chloro-(9CI)
- CAS No.
- 58142-49-7
- Chemical Name:
- 5-Isoquinolinamine,3-chloro-(9CI)
- Synonyms
- 3-CHLOROISOQUINOLIN-5-AMINE;5-Amino-3-chloroisoquinoline;3-Chloro-isoquinolin-5-ylamine;3-Chloro-5-isoquinolinamine;3-Chloro-5-aminoisoquinoline;5-Isoquinolinamine, 3-chloro-;5-Isoquinolinamine,3-chloro-(9CI);5-Amino-3-chloroisoquinoline hydrochloride;5-Isoquinolinamine,3-chloro-(9CI) ISO 9001：2015 REACH
- CBNumber:
- CB31281146
- Molecular Formula:
- C9H7ClN2
- Molecular Weight:
- 178.62
- MDL Number:
- MFCD09999240
- MOL File:
- 58142-49-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chloroisoquinolin-5-amine 97% | AS45475 | 250mg | $174 |
| 3-Chloroisoquinolin-5-amine 97% | AS45475 | 1g | $348 |
| 3-Chloroisoquinolin-5-amine 97% | AS45475 | 5g | $1073 |
| 3-chloroisoquinolin-5-amine | 189170 | 100.00mg | $82 |
| 3-chloroisoquinolin-5-amine | 189170 | 250.00mg | $136 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
5-Isoquinolinamine,3-chloro-(9CI) price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS45475 | 3-Chloroisoquinolin-5-amine 97% | 58142-49-7 | 250mg | $174 | 2026-06-04 | Buy |
| Activate Scientific | AS45475 | 3-Chloroisoquinolin-5-amine 97% | 58142-49-7 | 1g | $348 | 2026-06-04 | Buy |
| Activate Scientific | AS45475 | 3-Chloroisoquinolin-5-amine 97% | 58142-49-7 | 5g | $1073 | 2026-06-04 | Buy |
| Matrix Scientific | 189170 | 3-chloroisoquinolin-5-amine | 58142-49-7 | 100.00mg | $82 | 2026-05-18 | Buy |
| Matrix Scientific | 189170 | 3-chloroisoquinolin-5-amine | 58142-49-7 | 250.00mg | $136 | 2026-05-18 | Buy |
5-Isoquinolinamine,3-chloro-(9CI) Chemical Properties,Uses,Production
Synthesis
10296-47-6
58142-49-7
General procedure for the synthesis of 3-chloro-5-aminoisoquinoline from 3-chloro-5-nitroisoquinoline: 3-chloro-5-nitroisoquinoline (2.3 g, 11.0 mmol) was dissolved in acetic acid (100 mL), followed by the addition of zinc powder (3.5 g, 55.1 mmol) in batches. The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography using dichloromethane solution containing 1% methanol as eluent to give the final 3-chloro-5-aminoisoquinoline as an off-white solid. The product was analyzed by mass spectrometry (ESI, m/z), which showed that the [M+1]+ peak was located at 179.0; the 1H NMR (300 MHz, DMSO-d6) δ-values were 8.98 (s, 1H), 8.13 (s, 1H), 7.40-7.35 (m, 1H), 7.28-7.25 (m, 1H), 6.90-6.87 (m, 1H) and 6.06.
References
[1] Patent: WO2015/188368, 2015, A1. Location in patent: Page/Page column 56-57
[2] Patent: WO2010/45401, 2010, A1. Location in patent: Page/Page column 89
[3] Patent: WO2010/45402, 2010, A1. Location in patent: Page/Page column 87
[4] Patent: US2005/113576, 2005, A1. Location in patent: Page/Page column 30
[5] Journal of Medicinal Chemistry, 2007, vol. 50, # 15, p. 3651 - 3660
5-Isoquinolinamine,3-chloro-(9CI) Preparation Products And Raw materials
5-Isoquinolinamine,3-chloro-(9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9609 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; 19817745290 | bd@blocksynth.com | China | 5971 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 | mina@chuanghaibio.com | China | 18114 | 58 |
View Lastest Price from 5-Isoquinolinamine,3-chloro-(9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 5-Isoquinolinamine,3-chloro-(9CI)
58142-49-7
|
$1.10 | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited |
-
- 5-Isoquinolinamine,3-chloro-(9CI)
58142-49-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
