4,6-Dimethyl-2-mercaptopyrimidine
- CAS No.
- 22325-27-5
- Chemical Name:
- 4,6-Dimethyl-2-mercaptopyrimidine
- Synonyms
- 4,6-DIMETHYLPYRIMIDINE-2-THIOL;4,6-dimethylpyrimidine-2-thione;DLMP;4,6-dimethylpyrimidine-2(1H)-thione;AKOS AU-SVL-0100;AKOS BBS-00007056;TIMTEC-BB SBB007591;4,6-Dimethyl-2-pyrim;LABOTEST-BB LT00143473;DiMethyl-2-pyriMidineth
- CBNumber:
- CB3147157
- Molecular Formula:
- C6H8N2S
- Molecular Weight:
- 140.21
- MDL Number:
- MFCD00006079
- MOL File:
- 22325-27-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4,6-DIMETHYL-PYRIMIDINE-2-THIOL AldrichCPR | R432288 | 50MG | $197 |
| 4,6-Dimethyl-2-mercaptopyrimidine >98.0%(T) | D1580 | 25g | $58 |
| 4,6-Dimethyl-2-mercaptopyrimidine >98.0%(T) | D1580 | 250g | $288 |
| 4,6-Dimethyl-2-mercaptopyrimidine | FD03382 | 250g | $150 |
| 4,6-Dimethyl-2-mercaptopyrimidine | FD03382 | 100g | $150 |
| More product size | |||
| Melting point | 213-216 °C (dec.)(lit.) |
|---|---|
| Boiling point | 212.9±23.0 °C(Predicted) |
| Density | 1.160 (estimate) |
| refractive index | 1.5047 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 8.46±0.10(Predicted) |
| form | solid |
| color | White to Yellow |
| BRN | 81330 |
| InChI | InChI=1S/C6H8N2S/c1-4-3-5(2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9) |
| InChIKey | RAFAYWADRVMWFA-UHFFFAOYSA-N |
| SMILES | C1(=S)NC(C)=CC(C)=N1 |
| CAS DataBase Reference | 22325-27-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | YGT3ZQ6LZP |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P280g-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UW5650000 | |||||||||
| HS Code | 29335995 | |||||||||
| NFPA 704 |
|
4,6-Dimethyl-2-mercaptopyrimidine price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R432288 | 4,6-DIMETHYL-PYRIMIDINE-2-THIOL AldrichCPR | 22325-27-5 | 50MG | $197 | 2026-04-30 | Buy |
| TCI Chemical | D1580 | 4,6-Dimethyl-2-mercaptopyrimidine >98.0%(T) | 22325-27-5 | 25g | $58 | 2026-04-30 | Buy |
| TCI Chemical | D1580 | 4,6-Dimethyl-2-mercaptopyrimidine >98.0%(T) | 22325-27-5 | 250g | $288 | 2026-04-30 | Buy |
| Biosynth | FD03382 | 4,6-Dimethyl-2-mercaptopyrimidine | 22325-27-5 | 250g | $150 | 2026-06-04 | Buy |
| Biosynth | FD03382 | 4,6-Dimethyl-2-mercaptopyrimidine | 22325-27-5 | 100g | $150 | 2026-06-04 | Buy |
4,6-Dimethyl-2-mercaptopyrimidine Chemical Properties,Uses,Production
Chemical Properties
Yellow fine crystalline powder
Synthesis Reference(s)
Tetrahedron Letters, 37, p. 2035, 1996 DOI: 10.1016/0040-4039(96)00211-0
Synthesis
17356-08-0
123-54-6
22325-27-5
Thiourea (19 g, 0.25 mol) and acetylacetone (25.8 mL, 0.25 mol) were mixed in 125 mL of ethanol in a reaction flask. The reaction mixture was refluxed in a water bath for 2 hours. After cooling slightly, 33.5 mL of concentrated hydrochloric acid was added slowly through a funnel and the reflux heating was continued until the reaction was completed. At the end of the reaction, yellow crystals were obtained by filtration. After removing the solvent, the remaining solution was heated and dissolved with 10% NaOH solution. The pH of the solution was adjusted to about 7, and then cooled at room temperature to obtain 4,6-dimethylpyrimidine-2-thiol as pale yellow acicular crystals with 80.22% yield and melting point of 209-211 °C (literature value 210 °C).
References
[1] Bollettino chimico farmaceutico, 2004, vol. 143, # 7, p. 275 - 279
[2] Patent: CN105585538, 2016, A. Location in patent: Paragraph 0024
[3] Patent: CN105859693, 2016, A. Location in patent: Paragraph 0021
[4] Patent: CN105622599, 2016, A. Location in patent: Paragraph 0022
[5] Zeitschrift fur Anorganische und Allgemeine Chemie, 2015, vol. 641, # 7, p. 1301 - 1306
4,6-Dimethyl-2-mercaptopyrimidine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 4,6-Dimethyl-2-mercaptopyrimidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 4,6-Dimethyl-2-mercaptopyrimidine
22325-27-5
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-05-23 | 4,6-Dimethyl-2-mercaptopyrimidine
22325-27-5
|
$50.00-100.00 | 1kg | 99% | 20 tons | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2019-07-06 | 4,6-Dimethyl-2-mercaptopyrimidine
22325-27-5
|
$1.00 | 1kg | 98% | 100KG | Career Henan Chemical Co |
-
- 4,6-Dimethyl-2-mercaptopyrimidine
22325-27-5
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 4,6-Dimethyl-2-mercaptopyrimidine
22325-27-5
- $50.00-100.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- 4,6-Dimethyl-2-mercaptopyrimidine
22325-27-5
- $1.00
- 98%
- Career Henan Chemical Co
