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ChemicalBook >> CAS DataBase List >>2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE

CAS No.
78667-04-6
Chemical Name:
2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE
Synonyms
2-Chloromethyl-1-methyl-1H-imida;2-CHLOROMETHYL-1-METHYL-1H-IMIDAZOLE HCL;2-(Chloromethyl)-1-methylimidazole hydrochloride;1-Methyl-2-(chloromethyl)imidazole hydrochloride;2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE;2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95%;1H-IMidazole,2-(chloroMethyl)-1-Methyl-, hydrochloride (1:1)
CBNumber:
CB3168271
Molecular Formula:
C5H8Cl2N2
Molecular Weight:
167.04
MDL Number:
MFCD00234118
MOL File:
78667-04-6.mol
MSDS File:
SDS
Last updated:2026-05-28 01:01:26
Product description Number Pack Size Price
2-Chloromethyl-1-methyl-1H-imidazole HCl 98% AS74608 1g $51
2-Chloromethyl-1-methyl-1H-imidazole HCl 98% AS74608 5g $161
2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95% OR40445 250mg $21
2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 98%(GC) Y4093 1g $35
2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 98%(GC) Y4093 5g $114

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Properties

Melting point 175 °C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder
color Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933299090
NFPA 704
0
3 0

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS74608 2-Chloromethyl-1-methyl-1H-imidazole HCl 98% 78667-04-6 1g $51 2026-06-04 Buy
Activate Scientific AS74608 2-Chloromethyl-1-methyl-1H-imidazole HCl 98% 78667-04-6 5g $161 2026-06-04 Buy
Apolloscientific OR40445 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95% 78667-04-6 250mg $21 2026-06-04 Buy
AK Scientific Y4093 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 98%(GC) 78667-04-6 1g $35 2026-06-04 Buy
AK Scientific Y4093 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 98%(GC) 78667-04-6 5g $114 2026-06-04 Buy
Product number Packaging Price Buy
AS74608 1g $51 Buy
AS74608 5g $161 Buy
OR40445 250mg $21 Buy
Y4093 1g $35 Buy
Y4093 5g $114 Buy

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Chemical Properties,Uses,Production

Synthesis

(1-Methyl-1H-imidazol-2-yl)methanol

17334-08-6

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE

78667-04-6

General procedure for the synthesis of 2-(chloromethyl)-1-methyl-1H-imidazole hydrochloride (BB7) from 1-methyl-2-hydroxymethyl-1H-imidazole (BB6): to a solution of BB6 (35.5 g, 316.96 mmol) in dichloromethane (DCM, 1500 mL) was slowly added thionyl chloride (SOCl2, 330 mL, 4436 mmol ). The reaction mixture was gradually warmed to room temperature and stirred continuously for 5 hours. Upon completion of the reaction, the mixture was concentrated to remove the solvent. The residue was washed sequentially with dichloromethane (DCM, 2 × 500 mL) and ether (Et2O, 2 × 200 mL) to give the final target product BB7 (50 g, 95% yield) as an off-white solid. Thin-layer chromatography (TLC) showed an Rf value of 0.4 (unfolding agent: ethyl acetate).1H NMR (400 MHz, DMSO-d6) data were as follows: δ 7.76 (1H, apparent double peaks), 7.70 (1H, apparent double peaks), 5.17 (2H, single peak), 3.87 (3H, single peak); mass spectrometry (MS) showed an m/z of 131 ([M+H]+ ).

References

[1] Patent: US2012/322722, 2012, A1
[2] Tetrahedron Letters, 2011, vol. 52, # 41, p. 5308 - 5310
[3] Tetrahedron, 1996, vol. 52, # 48, p. 15171 - 15188
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993, # 19, p. 2291 - 2302
[5] Tetrahedron Letters, 2013, vol. 54, # 45, p. 6087 - 6089

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Preparation Products And Raw materials

2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE Suppliers

Global( 70)Suppliers
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CONIER CHEM AND PHARMA LIMITED
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DAYANG CHEM (HANGZHOU) CO.,LTD
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Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131956 58

View Lastest Price from 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE pictures 2020-01-03 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE
78667-04-6
$6.60 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co
2-CHLOROMETHYL-1-METHYL-1H-IMIDAZOLE HCL 2-(CHLOROMETHYL)-1-METHYL-1H-IMIDAZOLE HYDROCHLORIDE 1-Methyl-2-(chloromethyl)imidazole hydrochloride 2-(Chloromethyl)-1-methylimidazole hydrochloride 1H-IMidazole,2-(chloroMethyl)-1-Methyl-, hydrochloride (1:1) 2-(Chloromethyl)-1-methyl-1H-imidazole hydrochloride 95% 2-Chloromethyl-1-methyl-1H-imida 78667-04-6
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