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4-THIOURIDINE

4-THIOURIDINE structure

CAS No.: 13957-31-8

Chemical Name:: 4-THIOURIDINE

Synonyms: thiouridine;4-SH-Ur;NSC 518132;4-THIOURIDINE;THIOURIDINE, 4-;Uridine, 4-thio-;1-((2R,3R,4S,5R);4-Thio-D-uridine;4-thiouridineapprox.;4-Thiouridine【T4509】

CBNumber:: CB3202841

Molecular Formula:: C9H12N2O5S

Molecular Weight:: 260.27

MDL Number:: MFCD00006538

MOL File:: 13957-31-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 01:02:36

Product description	Number	Pack Size	Price
4-Thiouridine ≥98%	T4509	25mg	$248
4-Thiouridine ≥98%	T4509	100mg	$653
4-Thiouridine	T4059	25MG	$57
4-Thiouridine	T4059	100MG	$150
4-Thiouridine ≥98%	16373	5mg	$41
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4-THIOURIDINE Properties

Melting point	139-140℃ (ethanol )
Density	1.72±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
form	crystalline
pka	4.75±0.20(Predicted)
color	light yellow
PH	8.2
biological source	synthetic (organic)
Water Solubility	Soluble in water (20 mg/ml), and methanol (10 mg/ml).
λmax	245，331 (pH 6.5)；316 (pH 12)
InChI	InChI=1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1
InChIKey	ZLOIGESWDJYCTF-XVFCMESISA-N
SMILES	OC[C@H]1O[C@@H](N2C=CC(=S)NC2=O)[C@H](O)[C@@H]1O
CAS DataBase Reference	13957-31-8(CAS DataBase Reference)
FDA UNII	U9TYQ2R33J
UNSPSC Code	41106305
NACRES	NA.51

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338
PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	24/25
WGK Germany	3
HS Code	29349990
Storage Class	11 - Combustible Solids

4-THIOURIDINE price More Price(67)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	T4509	4-Thiouridine ≥98%	13957-31-8	25mg	$248	2026-04-30	Buy
Sigma-Aldrich	T4509	4-Thiouridine ≥98%	13957-31-8	100mg	$653	2026-04-30	Buy
TCI Chemical	T4059	4-Thiouridine	13957-31-8	25MG	$57	2026-04-30	Buy
TCI Chemical	T4059	4-Thiouridine	13957-31-8	100MG	$150	2026-04-30	Buy
Cayman Chemical	16373	4-Thiouridine ≥98%	13957-31-8	5mg	$41	2026-04-30	Buy

Product number	Packaging	Price	Buy
T4509	25mg	$248	Buy
T4509	100mg	$653	Buy
T4059	25MG	$57	Buy
T4059	100MG	$150	Buy
16373	5mg	$41	Buy

4-THIOURIDINE Chemical Properties,Uses,Production

Description

4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.

Uses

Nucleotide analogue, essential for cell growth in certain bacterial species. This compound is also able to chelate with certain metal ions, and in tRNA it can act as a built-in antiphotomutagenic agent that protects Escherichia coli cells against mutagenesis.

Uses

4-Thiouridine is a constituent of several transfer RNA's. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA.

Definition

ChEBI: A thiouridine in which the oxygen replaced by sulfur is that at C-4.

General Description

4-Thiouridine is a photoreactive uridine analog.

Biochem/physiol Actions

4-Thiouridine plays a role in assessing nascent RNA synthesis. It also enhances site-specific crosslinking. 4-Thiouridine also acts as a photoaffinity probe due to its stability even while lacking specific photoactivation. It can also be incorporated into RNAs.

storage

Store at -20°C

References

[1] KASPAR BURGER. 4-thiouridine inhibits rRNA synthesis and causes a nucleolar stress response.[J]. RNA Biology, 2013, 10 10: 1623-1630. DOI: 10.4161/rna.26214
[2] GILLES THOMAS Alain F. 4-Thiouridine Triggers Both Growth Delay Induced by Near-Ultraviolet Light and Photoprotection[J]. The FEBS journal, 1980, 113 1: 67-74. DOI: 10.1111/j.1432-1033.1980.tb06140.x
[3] MICHAEL E HARRIS E L C. RNA crosslinking methods.[J]. Methods in enzymology, 2009, 468: 127-146. DOI: 10.1016/s0076-6879(09)68007-1

4-THIOURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

4-THIOURIDINE Suppliers

Global( 187)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
NewCan Biotech Limited	+86-571-86912261 19975279805	sales@newcanbio.com	China	9985	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Nanjing Baifuli Technology Co., Ltd.	+86-15335185688	sales@unisyn.cn	CHINA	332	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5746	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
NewCan Biotech Limited	58
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58
Nanjing Baifuli Technology Co., Ltd.	58
BOC Sciences	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 4-THIOURIDINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-11	4-Thiouridine 13957-31-8	$40.00-129.00		99.97%	10g	TargetMol Chemicals Inc.
2025-04-02	4-Thiouridine;4-SH-Ur 13957-31-8		1g	97%	100g	NewCan Biotech Limited
2022-01-27	4-Thiouridine 13957-31-8		1KG	97.6%	100 tons	Honest Joy Holdings Limited

4-Thiouridine
13957-31-8
$40.00-129.00
99.97%
TargetMol Chemicals Inc.

4-Thiouridine;4-SH-Ur
13957-31-8
97%
NewCan Biotech Limited

4-Thiouridine
13957-31-8
$0.00
97.6%
Honest Joy Holdings Limited

4-THIOURIDINE Spectrum

4-THIOURIDINE(13957-31-8)¹HNMR 4-THIOURIDINE(13957-31-8)FT-IR

13957-31-8(4-THIOURIDINE)Related Search:

4-THIOURIDINE 2-THIOURIDINE 5-METHYL-2-THIOURIDINE 5-methylaminomethyl-2-thiouridine 5-FLUORO-2'-O-METHYL-4-THIOURIDINE

4-THIO-UMP DISODIUM SALT 5-BROMO-2'-DEOXY-4-THIOURIDINE,5-BROMO-2''-DEOXY-4-THIOURIDINE 98.0% 4-thiouridine triphosphate 2'-deoxy-4'-thiouridine 5-(2-bromovinyl)-2'-deoxy-4'-thiouridine

5-(carboxymethylaminomethyl)-2-thiouridine 2'-O-methyl-2-thiouridine 6-aza-2-thiouridine THIOURIDINE, 4-(RG) 4-THIOURIDINE-5'-TRIPHOSPHATE LITHIUM SALT

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1of4

1-((2R,3R,4S,5R) -4-thioxo-3,4-dihydropyrimidin-2(1H) THIOURIDINE, 4- 4-THIOURIDINE 4-thiouridineapprox. 4-Thio-D-uridine 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyriMidin-2(1H)-one 4-SH-Ur NSC 518132 Uridine, 4-thio- 4-THIOURIDINE USP/EP/BP 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one 4-thiouridine,RNA-modified nucleoside s4U 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-thioxo-pyrimidin-2-one 4-Thiouridine, RNA synthesis inhibitor 4-Thiouridine, 10 mM in DMSO 4-Thiouridine【T4509】 RNA-modified nucleoside s4U thiouridine 13957-31-8 Biochemicals and Reagents BioChemical Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs Biochemicals and Reagents Nucleoside Analogs Nucleosides, Nucleotides, Oligonucleotides Bases & Related Reagents Nucleotides Sulfur & Selenium Compounds

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4-THIOURIDINE

4-THIOURIDINE Properties

SAFETY

Risk and Safety Statements

4-THIOURIDINE price More Price(67)

4-THIOURIDINE Chemical Properties,Uses,Production

Description

Uses

Uses

Definition

General Description

Biochem/physiol Actions

storage

References

4-THIOURIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

4-THIOURIDINE Suppliers

View Lastest Price from 4-THIOURIDINE manufacturers

4-THIOURIDINE Spectrum

13957-31-8(4-THIOURIDINE)Related Search: