4-(HYDROXYMETHYL)PHENYL PIVALATE
- CAS No.
- 59012-91-8
- Chemical Name:
- 4-(HYDROXYMETHYL)PHENYL PIVALATE
- Synonyms
- 4-(HydroxyMethyl)phenol pivalate;4-(HYDROXYMETHYL)PHENYL PIVALATE;Propanoic acid, 2,2-dimethyl-, 4-(hydroxymethyl)phenyl ester
- CBNumber:
- CB32459737
- Molecular Formula:
- C12H16O3
- Molecular Weight:
- 208.25
- MDL Number:
- MFCD11616923
- MOL File:
- 59012-91-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-(Hydroxymethyl)phenyl pivalate 95% | AS114861 | 1g | $827 |
| 4-(Hydroxymethyl)phenyl pivalate | 305895 | 50.00mg | $102 |
| 4-(Hydroxymethyl)phenyl pivalate | 305895 | 100.00mg | $154 |
| 4-(Hydroxymethyl)phenyl pivalate | 305895 | 250.00mg | $276 |
| 4-(Hydroxymethyl)Phenyl Pivalate 95% | AA00EKPE | 50mg | $122 |
SAFETY
Risk and Safety Statements
| REACH Registrations | Active |
|---|
4-(HYDROXYMETHYL)PHENYL PIVALATE price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS114861 | 4-(Hydroxymethyl)phenyl pivalate 95% | 59012-91-8 | 1g | $827 | 2026-06-04 | Buy |
| Matrix Scientific | 305895 | 4-(Hydroxymethyl)phenyl pivalate | 59012-91-8 | 50.00mg | $102 | 2026-05-19 | Buy |
| Matrix Scientific | 305895 | 4-(Hydroxymethyl)phenyl pivalate | 59012-91-8 | 100.00mg | $154 | 2026-05-19 | Buy |
| Matrix Scientific | 305895 | 4-(Hydroxymethyl)phenyl pivalate | 59012-91-8 | 250.00mg | $276 | 2026-05-19 | Buy |
| aablocks | AA00EKPE | 4-(Hydroxymethyl)Phenyl Pivalate 95% | 59012-91-8 | 50mg | $122 | 2026-05-28 | Buy |
4-(HYDROXYMETHYL)PHENYL PIVALATE Chemical Properties,Uses,Production
Synthesis
623-05-2
3282-30-2
59012-91-8
Procedure for the synthesis of 4-(hydroxymethyl)phenyl trimethyl acetate (Compound M1): to a stirred solution of 4-hydroxybenzyl alcohol (6.21 g, 50 mmol) in anhydrous THF (50 mL) was added triethylamine (10.43 mL, 75 mmol) under the protection of argon, followed by a slow dropwise addition of pivaloyl chloride (6.79 mL, 55 mmol) at room temperature. The reaction mixture was continued to be stirred at room temperature for 60 minutes. Upon completion of the reaction, the reaction was quenched by the addition of water (0.2 mL) and the mixture was allowed to stand overnight. Subsequently, the reaction mixture was diluted with EtOAc (~400 mL) and washed sequentially with saturated NaHCO3 solution (3 x 100 mL) and brine (100 mL). The organic phase was dried with Na2SO4, filtered and concentrated. The product was purified by rapid chromatography on a silica gel column (4 × 20 cm) (TLC conditions: Rf = 0.4, unfolding agent was ethyl acetate/hexane (4:6)), and ethyl acetate/hexane (4:6) was used as eluent. The fractions containing the pure product were combined, concentrated and dried under vacuum to give 7.75 g (74% yield) of the target compound in the form of a colorless oil.1H NMR (DMSO-d6): δ 7.35 (d, 2H, J = 8.6 Hz), 7.04 (d, 2H, J = 8.6 Hz), 5.22 (t, 1H), 4.50 (d, 2H), 1.31 (s, 9H).
References
[1] Journal of Organic Chemistry, 2005, vol. 70, # 23, p. 9470 - 9479
[2] Journal of Organic Chemistry, 2006, vol. 71, # 22, p. 8651 - 8654
[3] Chemical Communications, 2018, vol. 54, # 61, p. 8466 - 8469
[4] Patent: WO2015/153496, 2015, A1. Location in patent: Paragraph 00201
[5] Patent: WO2015/153510, 2015, A1. Location in patent: Paragraph 00201
4-(HYDROXYMETHYL)PHENYL PIVALATE Preparation Products And Raw materials
Raw materials
Preparation Products
4-(HYDROXYMETHYL)PHENYL PIVALATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| Huida Pharmaceutical Technology (Shanghai) Co., Ltd. | +8613601750004 | lizhi@pharoschem.com | China | 439 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3280 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11780 | 60 |
| Zhengzhou GranLen pharmaceutical Technology Co., Ltd. | 0371-85513397 | info@granlen.com | China | 497 | 55 |
View Lastest Price from 4-(HYDROXYMETHYL)PHENYL PIVALATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | 4-(Hydroxymethyl)phenol pivalate
59012-91-8
|
10g | TargetMol Chemicals Inc. | ||||
 |
2023-12-04 | 4-(HYDROXYMETHYL)PHENYL PIVALATE
59012-91-8
|
98% | 100kg | Huida Pharmaceutical Technology (Shanghai) Co., Ltd. |
-
- 4-(Hydroxymethyl)phenol pivalate
59012-91-8
- TargetMol Chemicals Inc.
-
- 4-(HYDROXYMETHYL)PHENYL PIVALATE
59012-91-8
- 98%
- Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
