5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenamine
- CAS No.
- 116233-17-1
- Chemical Name:
- 5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenamine
- Synonyms
- 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine;5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenamine;2-Naphthalenamine, 5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-
- CBNumber:
- CB32503254
- Molecular Formula:
- C15H23N
- Molecular Weight:
- 217.35
- MDL Number:
- MOL File:
- 116233-17-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | P58447 | 100mg | $125 |
| 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | P58447 | 250mg | $135 |
| 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | P58447 | 1g | $140 |
| 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | P58447 | 5g | $500 |
| 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | CD12177156 | 1g | $248 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H332 |
| Precautionary statements | P280 |
5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenamine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | P58447 | 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | 116233-17-1 | 100mg | $125 | 2026-05-06 | Buy |
| Synthonix | P58447 | 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | 116233-17-1 | 250mg | $135 | 2026-05-06 | Buy |
| Synthonix | P58447 | 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | 116233-17-1 | 1g | $140 | 2026-05-06 | Buy |
| Synthonix | P58447 | 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | 116233-17-1 | 5g | $500 | 2026-05-06 | Buy |
| Crysdot | CD12177156 | 3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine 95+% | 116233-17-1 | 1g | $248 | 2026-05-27 | Buy |
5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenamine Chemical Properties,Uses,Production
Synthesis
116233-16-0
116233-17-1
3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-amine (6) was synthesized as follows: 1,1,4,4,6-pentamethyl-7-nitro-1,2,3,4-tetrahydronaphthalene (5) (2.5 g, 10.1 mmol) was dissolved in ethyl acetate (205 mL) to prepare a 0.05 M solution. The hydrogenation reaction was repeated twice using a ThalesNano H-cubereactor at 70°C and 2-5 bar pressure through a 10 mL Pd/C cartridge at a flow rate of 1.0 mL/min. Upon completion of the reaction, the resulting solution was concentrated under vacuum to afford the target product 6 (2.13 g, 97% yield) as a yellow crystalline solid with a melting point of 205°C. The structure of the product was confirmed by the following characterization data: 1H NMR (400 MHz, CDCl3) δ 7.00 (s, 1H), 6.63 (s, 1H), 3.34 (br s, 2H), 2.15 (s, 3H), 1.63 (s, 4H), 1.26 (s, 12H); 13C NMR (100.6 MHz, CDCl3) δ 143.5, 142.0, 135.2, 128.3, 120.5, 112.6, 35.3, 35.2, 33.8, 33.4, 32.0, 31.8, 17.1; IR ( neat)ν 3404, 3335, 2956, 2925, 1626, 1504 cm-1; LC-MS-CI (M+H)+ calculated value C15H24N 218.1909, measured value 218.1908.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 9, p. 2352 - 2356
[2] Patent: WO2015/130973, 2015, A1. Location in patent: Page/Page column 20; 21
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 19, p. 8924 - 8940
[4] Patent: US2018/207156, 2018, A1. Location in patent: Paragraph 0114; 0131
[5] Journal of Medicinal Chemistry, 1989, vol. 32, # 7, p. 1504 - 1517
5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenamine Preparation Products And Raw materials
Raw materials
Preparation Products
5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenamine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou HQ Material CO.,LTD. | +86-371-55919009 +8615225108189 | sale1@hqmat.com | China | 1100 | 58 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9976 | 60 |
| Shanghai Synteam Biochem CO.,ltd | +86-021-58380978 13482386415 | info@systeambc.com | China | 898 | 50 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Xi'an Kaixiang Photoelectric Technology Co., Ltd. | 18592059708 | sales@kxmaterials.com | China | 987 | 55 |
| Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd. | 027-51831887 15337167856 | hubeixinyuanshun@163.com | China | 10295 | 58 |
| Springchem New Material Technology Co.,Ltd | 021-52836897 13917661608 | info@spring-chem.com | China | 2000 | 58 |
| Zhengzhou Convergence Chemical Co. LTD | 13393710386 | 3941078109@qq.com | China | 9842 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 45000 | 58 |
| Wuhan Wenjin Chemical Technology Co., Ltd. | 13517196568 | 375665891@qq.com | China | 499 | 58 |
