1-(6-Chloro-3-pyridazinyl)-4-piperidinol
- CAS No.
- 89937-26-8
- Chemical Name:
- 1-(6-Chloro-3-pyridazinyl)-4-piperidinol
- Synonyms
- 1-(6-CHLOROPYRIDAZIN-3-YL)PIPERIDIN-4-OL;1-(6-CHLORO-3-PYRIDAZINYL)-4-PIPERIDINOL;1-(6-Chloro-3-pyridazinyl)piperidin-4-ol;4-Piperidinol, 1-(6-chloro-3-pyridazinyl)-;1-(6-Chloropyridazin-3-yl)piperidin-4-ol95%;1-(6-Chloropyridazin-3-yl)-4-hydroxypiperidine;1-(6-Chloro-pyridazino-3-yl)-4-hydroxypiperidine;1-(6-Chloro-3-pyridazinyl)-4-piperidinol ISO 9001：2015 REACH
- CBNumber:
- CB3258116
- Molecular Formula:
- C9H12ClN3O
- Molecular Weight:
- 213.66
- MDL Number:
- MFCD05864736
- MOL File:
- 89937-26-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | FC153681 | 0.5g | $150 |
| 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | FC153681 | 2g | $150 |
| 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | FC153681 | 1g | $150 |
| 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | FC153681 | 5g | $157.05 |
| 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | FC153681 | 10g | $251.3 |
| More product size | |||
| Boiling point | 453.3±45.0 °C(Predicted) |
|---|---|
| Density | 1.360±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | solid |
| pka | 14.52±0.20(Predicted) |
| InChI | 1S/C9H12ClN3O/c10-8-1-2-9(12-11-8)13-5-3-7(14)4-6-13/h1-2,7,14H,3-6H2 |
| InChIKey | GYVIZUPSUNWREG-UHFFFAOYSA-N |
| SMILES | OC1CCN(CC1)c2ccc(Cl)nn2 |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
1-(6-Chloro-3-pyridazinyl)-4-piperidinol price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FC153681 | 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | 89937-26-8 | 0.5g | $150 | 2026-06-04 | Buy |
| Biosynth | FC153681 | 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | 89937-26-8 | 2g | $150 | 2026-06-04 | Buy |
| Biosynth | FC153681 | 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | 89937-26-8 | 1g | $150 | 2026-06-04 | Buy |
| Biosynth | FC153681 | 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | 89937-26-8 | 5g | $157.05 | 2026-06-04 | Buy |
| Biosynth | FC153681 | 1-(6-Chloropyridazin-3-yl)piperidin-4-ol | 89937-26-8 | 10g | $251.3 | 2026-06-04 | Buy |
1-(6-Chloro-3-pyridazinyl)-4-piperidinol Chemical Properties,Uses,Production
Synthesis
5382-16-1
141-30-0
89937-26-8
General procedure: 3,6-dichloropyridazine (1 eq.), 4-hydroxypiperidine (1 eq.) and a nonprotonic base (e.g., Et3N or K2CO3, 2-3 eq.) are dissolved in DMSO or EtOH in a sealed vessel, and the reaction is heated until the feedstocks are shown to be completely consumed by TLC or HPLC monitoring. Upon completion of the reaction, post-treatment is carried out: the reaction mixture is partially evaporated, followed by the addition of water and filtration to collect the precipitated solid product (for cases such as 37); alternatively, the partially evaporated reaction mixture is partitioned between EtOAc and water, and the aqueous layer is extracted with EtOAc several times to ensure complete extraction. The organic layers are combined, dried over anhydrous Na2SO4 and concentrated under reduced pressure to give the crude product, which is finally purified by column chromatography.
References
[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 8, p. 1819 - 1839
[2] Patent: WO2016/54388, 2016, A1. Location in patent: Page/Page column 57
[3] Journal of Medicinal Chemistry, 1984, vol. 27, # 8, p. 1077 - 1083
[4] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 24, p. 7281 - 7286
[5] Patent: WO2008/46226, 2008, A1. Location in patent: Page/Page column 42
1-(6-Chloro-3-pyridazinyl)-4-piperidinol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3957 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 1-(6-Chloro-3-pyridazinyl)-4-piperidinol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-04-30 | 1-(6-Chloropyridazin-3-yl)piperidin-4-ol
89937-26-8
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-08 | 1-(6-Chloro-3-pyridazinyl)-4-piperidinol
89937-26-8
|
1KG | 98%; 99% | 1kg; 10kg; 25kg | Career Henan Chemical Co |
-
- 1-(6-Chloropyridazin-3-yl)piperidin-4-ol
89937-26-8
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(6-Chloro-3-pyridazinyl)-4-piperidinol
89937-26-8
- $0.01
- 98%; 99%
- Career Henan Chemical Co
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