TN ANTIGEN
- CAS No.
- 67262-86-6
- Chemical Name:
- TN ANTIGEN
- Synonyms
- TN EPITOPE;TN ANTIGEN;GALNAC-ALPHA1-O-SER;GalNac-α-1-O-serine;Ser(α-D-GalNHAc)-OH;Olanzapine Impurity 50;Tn Antigen: H-Ser(α-D-GalNAc)-OH;Galactose Impurity 9 (Tn Epitope);N-ACETYLGALACTOSAMINE, ALPHA1-O-SERINE;N-Acetyl-α-D-galactosaMinyl- 1-O-serine
- CBNumber:
- CB3283024
- Molecular Formula:
- C11H20N2O8
- Molecular Weight:
- 308.29
- MDL Number:
- MFCD01863462
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Tn Antigen ≥99.0% (TLC) | 53886 | 1mg | $446 |
| 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | MA07378 | 2mg | $547.7 |
| 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | MA07378 | 5mg | $1225.15 |
| 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | MA07378 | 10mg | $2161.9 |
| 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | MA07378 | 25mg | $4323.75 |
| More product size | |||
| Melting point | 198-201°C |
|---|---|
| Boiling point | 701.2±60.0 °C(Predicted) |
| Density | 1.51±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Water |
| pka | 2.05±0.10(Predicted) |
| form | Solid |
| color | Off-White to Yellow |
| Stability | HYGROSCOPIC |
| InChI | 1S/C11H20N2O8/c1-4(15)13-7-9(17)8(16)6(2-14)21-11(7)20-3-5(12)10(18)19/h5-9,11,14,16-17H,2-3,12H2,1H3,(H,13,15)(H,18,19)/t5-,6+,7+,8-,9+,11-/m0/s1 |
| InChIKey | REDMNGDGDYFZRE-WKWISIMFSA-N |
| SMILES | CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@H](N)C(O)=O |
| UNSPSC Code | 12352204 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
TN ANTIGEN price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 53886 | Tn Antigen ≥99.0% (TLC) | 67262-86-6 | 1mg | $446 | 2026-04-30 | Buy |
| Biosynth | MA07378 | 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | 67262-86-6 | 2mg | $547.7 | 2026-06-04 | Buy |
| Biosynth | MA07378 | 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | 67262-86-6 | 5mg | $1225.15 | 2026-06-04 | Buy |
| Biosynth | MA07378 | 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | 67262-86-6 | 10mg | $2161.9 | 2026-06-04 | Buy |
| Biosynth | MA07378 | 2-Acetamido-2-deoxy-a-D-galactopyranosyl serine | 67262-86-6 | 25mg | $4323.75 | 2026-06-04 | Buy |
TN ANTIGEN Chemical Properties,Uses,Production
Chemical Properties
TN ANTIGEN is Yellow Solid
Uses
TN ANTIGEN is a cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines
Uses
A cancer associated carbohydrate tumor antigen which may be effective as cancer specific targets for immunotherapy as well as in the development of diagnostic monoclonal antibodies. Has been used or considered for use in human vaccines.
Definition
ChEBI: O-(N-acetyl-alpha-D-galactosaminyl)-L-serine is a non-proteinogenic L-amino acid that is N-acetyl-alpha-D-galactosamine linked via an alpha glycosidic bond to the O at position 3 of L-serine. It has a role as a tumour antigen. It is a L-serine derivative and a non-proteinogenic L-alpha-amino acid.
General Description
Tn antigenis a truncated O-glycan, that is commonly noticed in colorectal cancer (CRC). It is usually expressed at high levels in cancer cells. Tn antigen is small in size and simple in structure. It has a non-physiological glycan structure in humans, hence it may be identified as foreign by the immune system.
Biochem/physiol Actions
Tn antigen stimulates colorectal cancer metastasis through the activation of epithelial-mesenchymal transition, mediated by H-Ras. It acts as a precursor to several significant complex O-glycans. Subpopulations of blood cells in all lineages carrying the Tn antigen results in a hematological disorder called Tn syndrome.
TN ANTIGEN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Young Lively PharminBlock Co.,Ltd | +undefined18600731423 | jason_gao@yl-pharminblock.com | China | 1944 | 58 |
| Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046; | sales01@watsonbiotech.cn | China | 5733 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4784 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 13636370518 | shyysw007@163.com | China | 89686 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57422 | 58 |
