4-Morpholinobenzaldehyde
- CAS No.
- 1204-86-0
- Chemical Name:
- 4-Morpholinobenzaldehyde
- Synonyms
- 4-(4-FORMYLPHENYL)MORPHOLINE;4-(4-MORPHOLINYL)BENZALDEHYDE;4-MORPHOLINOBENZENECARBALDEHYDE;4-MORPHOLIN-4-YL-BENZALDEHYDE;AKOS BC-2976;AKOS BBS-00004794;BUTTPARK 98\50-29;IFLAB-BB F1274-0239;TIMTEC-BB SBB000299;SALOR-INT L481084-1EA
- CBNumber:
- CB3312111
- Molecular Formula:
- C11H13NO2
- Molecular Weight:
- 191.23
- MDL Number:
- MFCD00735826
- MOL File:
- 1204-86-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-(4-Morpholinyl)benzaldehyde 97% | 678813 | 5g | $121 |
| 4-(4-Formylphenyl)morpholine >98.0%(GC) | M1625 | 1g | $20 |
| 4-(4-Formylphenyl)morpholine >98.0%(GC) | M1625 | 5g | $51 |
| 4-Morpholinobenzaldehyde 98% | AS20626 | 1g | $24 |
| 4-Morpholinobenzaldehyde 98% | AS20626 | 5g | $46 |
| More product size | |||
| Melting point | 65-69 °C |
|---|---|
| Boiling point | 365.5±37.0 °C(Predicted) |
| Density | 1.163±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 1.87±0.40(Predicted) |
| color | Light yellow to Yellow to Orange |
| CAS DataBase Reference | 1204-86-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS06,GHS08,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H331-H302-H315-H318-H361-H370-H372-H317-H341-H351-H412-H226 |
| Precautionary statements | P501-P273-P272-P260-P270-P202-P240-P210-P233-P201-P243-P241-P242-P271-P264-P280-P370+P378-P308+P311-P362+P364-P303+P361+P353-P333+P313-P301+P312+P330-P304+P340+P311-P305+P351+P338+P310-P403+P233-P403+P235-P405 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39-24/25 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 29349990 |
4-Morpholinobenzaldehyde price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 678813 | 4-(4-Morpholinyl)benzaldehyde 97% | 1204-86-0 | 5g | $121 | 2026-04-30 | Buy |
| TCI Chemical | M1625 | 4-(4-Formylphenyl)morpholine >98.0%(GC) | 1204-86-0 | 1g | $20 | 2026-04-30 | Buy |
| TCI Chemical | M1625 | 4-(4-Formylphenyl)morpholine >98.0%(GC) | 1204-86-0 | 5g | $51 | 2026-04-30 | Buy |
| Activate Scientific | AS20626 | 4-Morpholinobenzaldehyde 98% | 1204-86-0 | 1g | $24 | 2026-06-04 | Buy |
| Activate Scientific | AS20626 | 4-Morpholinobenzaldehyde 98% | 1204-86-0 | 5g | $46 | 2026-06-04 | Buy |
4-Morpholinobenzaldehyde Chemical Properties,Uses,Production
Uses
4-Morpholinobenzaldehyde is mainly used as a raw material for organic synthesis. It can be used to prepare dihydrotetrazolopyrimidine derivatives (ethyl 5-methyl-7-(4-morpholinophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate), coumarin-based chalcone derivatives ((E)-3-[3-(4-(4-morpholinophenyl)acryloyl]-2H-chromen-2-one) and Ru(II) polypyridine complexes, among others.
Synthesis
110-91-8
459-57-4
1204-86-0
General procedure for the synthesis of 4-(4-morpholine)benzaldehyde from morpholine and p-fluorobenzaldehyde: In a dry reaction flask, p-fluorobenzaldehyde (25.0 g, 0.200 mol), morpholine (0.300 mol), and anhydrous potassium carbonate (40.0 g) were dissolved in N,N-dimethylformamide (DMF, 300 mL), and a catalytic amount of Aliquat 336 reagent. The reaction mixture was stirred at reflux for 24 hours at 100°C. Upon completion of the reaction, the mixture was concentrated to dryness under reduced pressure and cooled to room temperature. Subsequently, the concentrate was slowly poured into ice water and allowed to stand overnight. The precipitated solid was collected by filtration, washed with water and recrystallized with methanol to afford the target compound 4-morpholino benzaldehyde (Id) in 89% yield as yellow crystals with a melting point of 69 °C (in agreement with literature reports) [49,50].
References
[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 6, p. 2747 - 2759
[2] Bioorganic Chemistry, 2014, vol. 57, p. 65 - 82
[3] European Journal of Medicinal Chemistry, 2018, vol. 144, p. 68 - 81
[4] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 12, p. 3721 - 3725
[5] Russian Journal of General Chemistry, 2013, vol. 83, # 10, p. 1864 - 1868
4-Morpholinobenzaldehyde Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10457 | 58 |
View Lastest Price from 4-Morpholinobenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 4-Morpholinobenzaldehyde
1204-86-0
|
$1.00 | 1g | 99% | 10000KGS | Career Henan Chemical Co |
-
- 4-Morpholinobenzaldehyde
1204-86-0
- $1.00
- 99%
- Career Henan Chemical Co
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