CGS 15943
- CAS No.
- 104615-18-1
- Chemical Name:
- CGS 15943
- Synonyms
- CGS 15943;CGS-15943A;CGS-15943 solid;CGS 15943, 10 mM in DMSO;CGS-15943 ADENOSINE A1 RECEPTOR;9-CHLORO-2-(2-FURYL)(1,2,4)TRIAZOLO(1,5-C)QUINAZOLIN-5-AMINE;9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine;9-CHLORO-2-(2-FURANYL)-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE;9-Chloro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine;[1,2,4]Triazolo[1,5-c]quinazolin-5-amine,9-chloro-2-(2-furanyl)-
- CBNumber:
- CB3351424
- Molecular Formula:
- C13H8ClN5O
- Molecular Weight:
- 285.69
- MDL Number:
- MFCD01529897
- MOL File:
- 104615-18-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| CGS-15943 solid | C199 | 25mg | $176 |
| CGS 15943 ≥95% | 22073 | 5mg | $37 |
| CGS 15943 ≥95% | 22073 | 10mg | $69 |
| CGS 15943 ≥95% | 22073 | 25mg | $158 |
| CGS 15943 ≥95% | 22073 | 50mg | $280 |
| More product size | |||
| Melting point | 278-279 °C |
|---|---|
| Density | 1.72±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: >16 mg/mL |
| pka | 1.23±0.30(Predicted) |
| form | solid |
| color | white |
| InChI | 1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16) |
| InChIKey | MSJODEOZODDVGW-UHFFFAOYSA-N |
| SMILES | Nc1nc2ccc(Cl)cc2c3nc(nn13)-c4ccco4 |
| FDA UNII | Y5A5D5E2AQ |
| UNSPSC Code | 12352202 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
CGS 15943 price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C199 | CGS-15943 solid | 104615-18-1 | 25mg | $176 | 2026-04-30 | Buy |
| Cayman Chemical | 22073 | CGS 15943 ≥95% | 104615-18-1 | 5mg | $37 | 2026-04-30 | Buy |
| Cayman Chemical | 22073 | CGS 15943 ≥95% | 104615-18-1 | 10mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 22073 | CGS 15943 ≥95% | 104615-18-1 | 25mg | $158 | 2026-04-30 | Buy |
| Cayman Chemical | 22073 | CGS 15943 ≥95% | 104615-18-1 | 50mg | $280 | 2026-04-30 | Buy |
CGS 15943 Chemical Properties,Uses,Production
Uses
Potent adenosine receptor antagonist
Definition
ChEBI: A member of the class of triazoloquinazolines that is [1,2,4]triazolo[1,5-c]quinazoline substited at positions 2, 5 and 9 by furan-2-yl, amino and chloro groups respectively. A potent antagonist at adenosine A1 and adenosi e A2A receptors.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 27, p. 1549, 1990 DOI: 10.1002/jhet.5570270605
Biological Activity
Potent adenosine receptor antagonist (K i values are 3.5, 4.2, 16 and 51 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively). Orally active in vivo .
Biochem/physiol Actions
CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity.
storage
Store at RT
CGS 15943 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2782 | 58 |
