BAPTA
- CAS No.
- 85233-19-8
- Chemical Name:
- BAPTA
- Synonyms
- Glycine, N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxyMethyl)-;BAPTA;CS-2002;BAPTA,97%;BAPTA, >=98%;BAPTA, Free Acid;BAPTA, 10 mM in DMSO;85233-19-8(free acid);BAPTA, extracellular calcium chelator;1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'- TETRAACETI
- CBNumber:
- CB3406887
- Molecular Formula:
- C22H24N2O10
- Molecular Weight:
- 476.43
- MDL Number:
- MFCD00036255
- MOL File:
- 85233-19-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 14510 | 1G | $280 |
| 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 14510 | 50G | $3850 |
| 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 14510 | 100MG | $62.37 |
| 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 14510 | 250MG | $105.5 |
| 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid >97.0%(HPLC) | B3895 | 1g | $97 |
| More product size | |||
| Melting point | 177-179 °C |
|---|---|
| Boiling point | 575.89°C (rough estimate) |
| Density | 1.4482 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| RTECS | MC0423000 |
| storage temp. | 2-8°C |
| solubility | Soluble in dimethyl sulfoxide |
| form | Powder |
| pka | 1.40±0.10(Predicted) |
| color | White to off-white |
| Appearance | Solid Powder |
| Water Solubility | Soluble in water and sodium bicarbonate. |
| λmax | 209 nm, 254 nm, 203 nm, 274 nm |
| Merck | 14,957 |
| BRN | 5192406 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
| Biological Applications | Calcium indicators; zinc indicators; treating acute cell death,cerebral infarction,myocardial infarction,hepatonecrosis,kidney ischemic necrosis,necrotizing pancreatitis,amyloidosis,atherosclerosis,diseases characteriz |
| InChIKey | FTEDXVNDVHYDQW-UHFFFAOYSA-N |
| SMILES | OC(=O)CN(CC(O)=O)c1ccccc1OCCOc2ccccc2N(CC(O)=O)CC(O)=O |
| CAS DataBase Reference | 85233-19-8(CAS DataBase Reference) |
| FDA UNII | K22DDW77C0 |
| UNSPSC Code | 12352112 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29225090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
BAPTA price More Price(105)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 14510 | 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 85233-19-8 | 1G | $280 | 2026-04-30 | Buy |
| Sigma-Aldrich | 14510 | 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 85233-19-8 | 50G | $3850 | 2026-04-30 | Buy |
| Sigma-Aldrich | 14510 | 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 85233-19-8 | 100MG | $62.37 | 2025-07-31 | Buy |
| Sigma-Aldrich | 14510 | 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) | 85233-19-8 | 250MG | $105.5 | 2025-07-31 | Buy |
| TCI Chemical | B3895 | 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid >97.0%(HPLC) | 85233-19-8 | 1g | $97 | 2026-04-30 | Buy |
BAPTA Chemical Properties,Uses,Production
Description
BAPTA free acid (85233-19-8) is a selective extracellular Ca2+ chelator. It is a widely used calcium sponge for chelating Ca2+outside of intact cells.1 It’s a useful tool to probe the involvement of extracellular Ca2+ in cellular signaling.2,3 Non-cell-permeable.
Chemical Properties
White Solid
Uses
Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels.
Uses
As calcium chelator; 19F labelled forms for measurement of intracellular calcium.
Uses
BAPTA is a highly selective calcium chelating reagent. Lipophilic diesters of the chelating agent 1,2-Bis(2 aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) are used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE.
Definition
ChEBI: A polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene.
General Description
In nature 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetra acetic acid (BAPTA) is a main metabolic product of BAPTA -AM (BAPTA-tetra(actoxymethyl ester), a neuro protective agent in cerebral ischemia, in rats.BAPTA is an intercellular Ca2+ chelator.
Biological Activity
Selective calcium chelator.
storage
Store at +4°C
References
[1] ALBERTO MU?OZ. Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus.[J]. PLoS ONE, 2015: e0138008. DOI:10.1371/journal.pone.0138008
[2] K. WOZNIAK. Extracellular Ca2+ Is Required for Fertilization in the African Clawed Frog, Xenopus laevis[J]. PLoS ONE, 2017. DOI:10.1371/journal.pone.0170405
[3] MIROSLAVA DIDIASOVA. STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.[J]. The Journal of Biological Chemistry, 2015: 11983-11999. DOI:10.1074/jbc.m114.598425
BAPTA Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
View Lastest Price from BAPTA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | BAPTA
85233-19-8
|
$33.00-90.00 | 97.21% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-17 | BAPTA
85233-19-8
|
$2.20-8.80 | 1kg | 99%min | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2021-07-02 | 1,2-Bis(2-Aminophenoxy)ethane-N,N,N",N"-tetraacetic acid 98%
85233-19-8
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- BAPTA
85233-19-8
- $33.00-90.00
- 97.21%
- TargetMol Chemicals Inc.
-
- BAPTA
85233-19-8
- $2.20-8.80
- 99%min
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 1,2-Bis(2-Aminophenoxy)ethane-N,N,N",N"-tetraacetic acid 98%
85233-19-8
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
85233-19-8(BAPTA)Related Search:
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