3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
- CAS No.
- 832695-88-2
- Chemical Name:
- 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
- Synonyms
- 3-(N-MethyL;aminocarbonyL;3-Borono-N-methylbenzamide;3-(Methylcarbamoyl)benzeneboronic acid;[3-(MethylcarbaMoyl)phenyl]boronic acid;3-(N-Methylcarbamoyl)benzeneboronic acid;3-(N-methylformionine)phenylboronic acid;3-(N-Methylcarbamoyl)phenylboronic acid,;3-(MethylaMinocarbonyl)benzeneboronic Acid;[3-(MethylaMinocarbonyl)phenyl]boronic Acid
- CBNumber:
- CB3430637
- Molecular Formula:
- C8H10BNO3
- Molecular Weight:
- 178.98
- MDL Number:
- MFCD04038918
- MOL File:
- 832695-88-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 283226 | 1g | $396 |
| 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 283226 | 2g | $571 |
| 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 283226 | 5g | $909 |
| 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 283226 | 10g | $1351 |
| 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 283226 | 25g | $2390 |
| More product size | |||
| Melting point | 114-124°C |
|---|---|
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 7.70±0.10(Predicted) |
| form | solid |
| color | white |
| CAS DataBase Reference | 832695-88-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-43-41-37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-39-36/37 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID price More Price(73)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 283226 | 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 832695-88-2 | 1g | $396 | 2026-06-03 | Buy |
| Usbiological | 283226 | 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 832695-88-2 | 2g | $571 | 2026-06-03 | Buy |
| Usbiological | 283226 | 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 832695-88-2 | 5g | $909 | 2026-06-03 | Buy |
| Usbiological | 283226 | 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 832695-88-2 | 10g | $1351 | 2026-06-03 | Buy |
| Usbiological | 283226 | 3-(N-Methylaminocarbonyl)benzeneboronic acid Asreported | 832695-88-2 | 25g | $2390 | 2026-06-03 | Buy |
3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID Chemical Properties,Uses,Production
Uses
3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID is used in the preparation of thiazolopyridinylacetamide derivatives and analogs for use as PI3K and mTOR kinase inhibitors.
Synthesis
3.0 g (8.85 mmol) of potassium phosphate heptahydrate, 1.50 g (5.90 mmol) of bis(boronic acid) pinacol ester B2(pin)2, 12 mg (0.015 mmol) of Xphos-Pd-G2, and 4 mg (0.008 mmol) of Xphos were added sequentially to a reaction vial with 6 mL of ethanol stirred to mix well, and then 0.36 mL (2.95 mmol) 3-(N-methylformylamino)chlorobenzene was added and the reaction was carried out at room temperature for 1 hour. The reaction solution was diluted by adding 5 mL of ethyl acetate, filtered through diatomaceous earth, washed with ethyl acetate, the filtrates were combined and concentrated under reduced pressure to obtain the crude product, which was separated by silica gel column chromatography, eluted with petroleum ether-ethyl acetate, to obtain 3-(N-methylformylammonio)phenylboronic acid pinacol ester. 3-(N-Methylformylammonio)phenylboronic acid pinacol ester was added to a reaction vial and hydrolyzed dropwise with dilute HCl. The solution first produced a precipitate, and as the precipitate gradually disappeared, the pH of the system was adjusted to 1. NaOH solution with a mass fraction of 25% was added dropwise to the solution to pH 13, and stirred for 1 h. The solution was partitioned, and the organic phase was extracted with 15 mL of NaOH with a mass fraction of 10%, and the aqueous phases were combined, and the bases were extracted with 15 mL of THF for 2 times, respectively. The pH of the obtained base solution was adjusted with dilute HCl, turbidity was produced at the beginning, flocculent appeared slowly, and the pH was adjusted to 5.0. The aqueous phase was extracted with 70 mL of THF, and the organic phase was spin-dried and purified to obtain 3-(N-methylformylamino)phenylboronic acid.
3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-07-13 | 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
832695-88-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
832695-88-2
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
832695-88-2
|
$1.00 | 1KG | 97%-99% | 1kg;5kg;100kg | Career Henan Chemical Co |
-
- 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
832695-88-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
832695-88-2
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-(N-METHYLAMINOCARBONYL)PHENYLBORONIC ACID
832695-88-2
- $1.00
- 97%-99%
- Career Henan Chemical Co
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