20-HEPE
- CAS No.
- 116477-57-7
- Chemical Name:
- 20-HEPE
- Synonyms
- 20-HEPE;20-hydroxy-5(Z),8(Z),11(Z),14(Z),17(Z)-EPA;20-hydroxy-5(Z),8(Z),11(Z),14(Z),17(Z)-eicosapentaenoic acid;5,8,11,14,17-Eicosapentaenoic acid, 20-hydroxy-, (5Z,8Z,11Z,14Z,17Z)-
- CBNumber:
- CB34666883
- Molecular Formula:
- C20H30O3
- Molecular Weight:
- 318.45
- MDL Number:
- MOL File:
- 116477-57-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 20-HEPE ≥95% | 19322 | 25μg | $286 |
| 20-HEPE ≥95% | 19322 | 50μg | $544 |
| 20-HEPE ≥95% | 19322 | 100μg | $1030 |
| 20-HEPE ≥95% | 19322 | 25μg | $260 |
| 20-HEPE ≥95% | 19322 | 50μg | $494 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H336 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| NFPA 704 |
|
20-HEPE price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19322 | 20-HEPE ≥95% | 116477-57-7 | 25μg | $286 | 2026-04-30 | Buy |
| Cayman Chemical | 19322 | 20-HEPE ≥95% | 116477-57-7 | 50μg | $544 | 2026-04-30 | Buy |
| Cayman Chemical | 19322 | 20-HEPE ≥95% | 116477-57-7 | 100μg | $1030 | 2026-04-30 | Buy |
| Cayman Chemical | 19322 | 20-HEPE ≥95% | 116477-57-7 | 25μg | $260 | 2024-03-01 | Buy |
| Cayman Chemical | 19322 | 20-HEPE ≥95% | 116477-57-7 | 50μg | $494 | 2024-03-01 | Buy |
20-HEPE Chemical Properties,Uses,Production
Uses
20-HEPE is a metabolite of eicosapentaenoic acid formed by ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. At 10 μM, it activates peroxisome proliferator-activated receptor α (PPARα) in COS-7 cells expressing a luciferase reporter gene. 20-HEPE also activates mouse transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks analgesic activity in rats.
Definition
ChEBI: 20-HEPE is a HEPE obtained by hydroxylation at position 20 of all-cis-5,8,11,14,17-icosapentaenoic acid. It is a HEPE and a homoallylic alcohol. It is functionally related to an all-cis-5,8,11,14,17-icosapentaenoic acid. It is a conjugate acid of a 20-HEPE(1-).
References
[1] Harmon, et al. Oxygenation of ω-3 fatty acids by human cytochrome P450 4F3B: Effect on 20-hydroxyeicosatetraenoic acid production. Prostaglandins Leukot. Essent. Fatty Acids 75(3), 169-177 (2006).
20-HEPE Preparation Products And Raw materials
Raw materials
Preparation Products
20-HEPE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32468 | 58 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24960 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11972 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 13816009161 18217024652 | tech@zzbioco.com | China | 12064 | 58 |
