ANTI-HUMAN RB (AA 300-380)
- CAS No.
- Chemical Name:
- ANTI-HUMAN RB (AA 300-380)
- Synonyms
- ANTI-RB;RB (AB-5);ANTI-PP105;ANTI-RB(AB-2);ANTI-RB(AB-6);ANTI-RB (AB-5);ANTI-RB (AB-1);ANTI-RB PROTEIN;ANTI-PP105 (AB-1);ANTI-HUMAN RB(AB-5)
- CBNumber:
- CB3681006
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00282455
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| Anti- RB antibody produced in rabbit | SAB5701471 | 100 μL | $448 |
| Anti- RB antibody produced in rabbit | SAB5700862 | 100 μL | $448 |
| Anti-RB antibody produced in rabbit | SAB5700023 | 100μL | $448 |
| Anti-Retinoblastoma antibody produced in rabbit affinity isolated antibody | SAB4502591 | 100μg | $560 |
| Anti-Retinoblastoma antibody produced in rabbit affinity isolated antibody | SAB4502590 | 100μg | $560 |
ANTI-HUMAN RB (AA 300-380) price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB5701471 | Anti- RB antibody produced in rabbit | 100 μL | $448 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB5700862 | Anti- RB antibody produced in rabbit | 100 μL | $448 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB5700023 | Anti-RB antibody produced in rabbit | 100μL | $448 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB4502591 | Anti-Retinoblastoma antibody produced in rabbit affinity isolated antibody | 100μg | $560 | 2026-04-30 | Buy | |
| Sigma-Aldrich | SAB4502590 | Anti-Retinoblastoma antibody produced in rabbit affinity isolated antibody | 100μg | $560 | 2026-04-30 | Buy |
ANTI-HUMAN RB (AA 300-380) Chemical Properties,Uses,Production
Uses
["Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Inhibits the intrinsic kinase activity of TAF1. In case of viral infections, interactions with SV40 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity.", 'The gene encoding Retinoblastoma-associated protein (RB1) is a tumor suppressor gene localized on human chromosome 13q14.2.']
Biological Activity
Retinoblastoma-associated protein (RB1) modulates the cell cycle. It acts as a repressor of transcription mediated by E2 factor (E2F) and influences transcriptional silencing. RB1 modulates mitochondrial activities and has a role in the organisation of heterochromatin. Mutations in the gene encoding this protein have been associated with childhood retinoblastoma.
ANTI-HUMAN RB (AA 300-380) Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN RB (AA 300-380) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Merck KGaA | -- | ordercn@merckgroup.com | China | 6394 | 58 |
| Nanjing Weiwo Biotechnology Co., Ltd. | -- | CHINA | 6423 | 58 |
| Supplier | Advantage |
|---|---|
| Merck KGaA | 58 |
| Nanjing Weiwo Biotechnology Co., Ltd. | 58 |
