2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE
![2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE Structure](CAS/GIF/209959-33-1.gif)
- CAS No.
- 209959-33-1
- Chemical Name:
- 2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE
- Synonyms
- 5-Bromo-N,N-di-Boc-pyrimidin-2-amine;N,N-bis-Boc-2-aMino-5-broMopyriMidine;2-(N,N-BisBOC-Amino)-5-bromopyrimidine;2-Amino-5-bromopyrimidine, 2,2-Bis-BOC protected;2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE;(5-Bromopyrimidin-2-yl)bis(tert-butoxycarbonyl)amine;di-tert-butyl (5-bromopyrimidin-2-yl)imidodicarbonate;2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE, 95+%;2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE ISO 9001：2015 REACH;tert-butyl N-(5-broMopyriMidin-2-yl)-N-[(tert-butoxy)carbonyl]carbaMate
- CBNumber:
- CB3714843
- Molecular Formula:
- C14H20BrN3O4
- Molecular Weight:
- 374.23
- MDL Number:
- MFCD08275685
- MOL File:
- 209959-33-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| tert-Butyl N-(5-bromopyrimidin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate | 087299 | 500.00mg | $126 |
| tert-Butyl N-(5-bromopyrimidin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate | 087299 | 1.00g | $159 |
| tert-butyl N-(5-bromopyrimidin-2-yl)-N-[(tert- butoxy)carbonyl]carbamate 97.0% | B11138 | 25g | $60 |
| tert-butyl N-(5-bromopyrimidin-2-yl)-N-[(tert- butoxy)carbonyl]carbamate 97.0% | B11138 | 50g | $120 |
| tert-butyl N-(5-bromopyrimidin-2-yl)-N-[(tert- butoxy)carbonyl]carbamate 97.0% | B11138 | 100g | $200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 087299 | tert-Butyl N-(5-bromopyrimidin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate | 209959-33-1 | 500.00mg | $126 | 2026-05-18 | Buy |
| Matrix Scientific | 087299 | tert-Butyl N-(5-bromopyrimidin-2-yl)-N-[(tert-butoxy)carbonyl]carbamate | 209959-33-1 | 1.00g | $159 | 2026-05-18 | Buy |
| Synthonix | B11138 | tert-butyl N-(5-bromopyrimidin-2-yl)-N-[(tert- butoxy)carbonyl]carbamate 97.0% | 209959-33-1 | 25g | $60 | 2026-05-06 | Buy |
| Synthonix | B11138 | tert-butyl N-(5-bromopyrimidin-2-yl)-N-[(tert- butoxy)carbonyl]carbamate 97.0% | 209959-33-1 | 50g | $120 | 2026-05-06 | Buy |
| Synthonix | B11138 | tert-butyl N-(5-bromopyrimidin-2-yl)-N-[(tert- butoxy)carbonyl]carbamate 97.0% | 209959-33-1 | 100g | $200 | 2026-05-06 | Buy |
2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE Chemical Properties,Uses,Production
Synthesis
7752-82-1
24424-99-5
![2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE](/CAS/GIF/209959-33-1.gif)
209959-33-1
Step A: 2-Amino-5-bromopyrimidine (2.75 g, 15.8 mmol) and di-tert-butyl dicarbonate (7.58 g, 34.8 mmol) were dissolved in pyridine (30 mL) and the reaction was stirred at 70 °C overnight. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was extracted by partitioning with ethyl acetate (EtOAc) and 1N hydrochloric acid aqueous solution. The aqueous layer was extracted once more with ethyl acetate. The organic phases were combined, dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to give 2-[bis(tert-butoxycarbonyl)amino]-5-bromopyrimidine (5.5 g, 93% yield) as a white solid. Mass spectrometry (MS) analysis showed m/z 398.2 [M + Na]+.
References
[1] Patent: WO2013/101974, 2013, A1. Location in patent: Paragraph 00816; 00817
[2] Patent: US9617268, 2017, B2. Location in patent: Page/Page column 371
[3] Patent: WO2010/121164, 2010, A2. Location in patent: Page/Page column 93-94
[4] Patent: WO2017/176812, 2017, A1. Location in patent: Paragraph 0276
[5] Patent: EP946508, 2009, B1. Location in patent: Page/Page column 60
2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE Preparation Products And Raw materials
2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29120 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25356 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11680 | 58 |
| Xuzhou B&C Chemical Technology Co., Ltd | +86-400-0516-021 +86-15190678838 | info@bcpharma.com | China | 2732 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39021 | 58 |
| JiangXi Bobert Imp&Exp Co.,LTD | 18071643627 | rze2024@163.com | China | 226 | 58 |
View Lastest Price from 2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE pictures](/ProductImageEN/2021-12/Small/fbe54520-04fa-4ffe-a07d-943bc153b678.jpg) |
2025-11-18 | 2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE
209959-33-1
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 2-[BIS(TERT-BUTOXYCARBONYL)AMINO]-5-BROMOPYRIMIDINE
209959-33-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
