2-PYRAZOL-1-YL-PYRIDINE
- CAS No.
- 25700-11-2
- Chemical Name:
- 2-PYRAZOL-1-YL-PYRIDINE
- Synonyms
- 2-pyrazole-1-pyridine;2-PYRAZOL-1-YL-PYRIDINE;2-(1-Pyrazolyl)pyridine;2-(1H-pyrazol-1-yl)pyridine;2-(1-Pyrazolyl)pyridine >Pyridine, 2-(1H-pyrazol-1-yl)-
- CBNumber:
- CB3840494
- Molecular Formula:
- C8H7N3
- Molecular Weight:
- 145.16
- MDL Number:
- MFCD09033534
- MOL File:
- 25700-11-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-(1-Pyrazolyl)pyridine >98.0%(GC) | P2239 | 1g | $73 |
| 2-(1-Pyrazolyl)pyridine >98.0%(GC) | P2239 | 5g | $231 |
| 2-PYRAZOL-1-YL-PYRIDINE 97% | 65480 | 1G | $41 |
| 2-(1H-Pyrazol-1-yl)pyridine | ABA70011 | 5g | $437.5 |
| 2-(1H-Pyrazol-1-yl)pyridine 98% | OR302344 | 250mg | $21 |
| More product size | |||
| Melting point | 37.0 to 41.0 °C |
|---|---|
| Boiling point | 265.6±13.0 °C(Predicted) |
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to lump |
| pka | 2.83±0.10(Predicted) |
| color | White to Almost white |
| InChIKey | XXTPHXNBKRVYJI-UHFFFAOYSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
2-PYRAZOL-1-YL-PYRIDINE price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P2239 | 2-(1-Pyrazolyl)pyridine >98.0%(GC) | 25700-11-2 | 1g | $73 | 2026-04-30 | Buy |
| TCI Chemical | P2239 | 2-(1-Pyrazolyl)pyridine >98.0%(GC) | 25700-11-2 | 5g | $231 | 2026-04-30 | Buy |
| AstaTech | 65480 | 2-PYRAZOL-1-YL-PYRIDINE 97% | 25700-11-2 | 1G | $41 | 2026-04-30 | Buy |
| Biosynth | ABA70011 | 2-(1H-Pyrazol-1-yl)pyridine | 25700-11-2 | 5g | $437.5 | 2026-06-04 | Buy |
| Apolloscientific | OR302344 | 2-(1H-Pyrazol-1-yl)pyridine 98% | 25700-11-2 | 250mg | $21 | 2026-06-04 | Buy |
2-PYRAZOL-1-YL-PYRIDINE Chemical Properties,Uses,Production
Synthesis
288-13-1
109-04-6
25700-11-2
General procedure for the synthesis of 2-pyrazole-1-pyridine (Pyr-N-PzH) from pyrazole and 2-bromopyridine: To a 250 mL single-necked round-bottomed flask were added 15.0 g (95 mmol) of 2-bromopyridine, 25.0 g (367 mmol, 3.86 equiv) of pyrazole and 45 mL of xylene. The reaction mixture was heated to reflux for 8 hours and subsequently cooled to room temperature. The resulting mixture was dissolved in dichloromethane and the organic layer was washed four times with 250 mL of water (until pyrazole was not detected by gas chromatography). The organic layer was dried over anhydrous magnesium sulfate, filtered and rotary evaporated to give 12.0 g (82.6 mmol, 87% yield) of the target product as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 8.59 (m, 1H, pyridinyl 6-H), 8.39 (s, 1H, pyrazol-5-H), 7.90 (d, 1H, pyridinyl 3-H), 7.80 (m, 1H, pyridinyl 4-H), 7.73 (s, 1H, pyrazol 3-H), 7.15 (s, 1H, pyridinyl -5-H), 6.45 (m, 1H, pyrazole-4-H).
References
[1] Tetrahedron, 2010, vol. 66, # 47, p. 9141 - 9144
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 13, p. 4101 - 4114
[3] European Journal of Organic Chemistry, 2011, # 14, p. 2692 - 2696
[4] Journal of Organic Chemistry, 2005, vol. 70, # 13, p. 5164 - 5173
[5] Journal of Organic Chemistry, 2011, vol. 76, # 2, p. 654 - 660
2-PYRAZOL-1-YL-PYRIDINE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24529 | 81 |
| Nanjing Norris-Pharm Technology Co., Ltd | 18652989687 | sales@norris-pharm.com | China | 8878 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28387 | 80 |
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