ChemicalBook >> CAS DataBase List >>1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester structure

CAS No.: 37813-30-2

Chemical Name:: 1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

Synonyms: 37813-30-2);Boc-L-Hyp-oet;BOC-L-Proline Ethyl ester;Boc-L-Hydroxy-Proline Ethyl Ester;1-Boc-L-hydroxyproline ethyl ester;1-Boc-4-Hydroxy-L-Proline Ethyl Ester;(Tert-Butoxy)Carbonyl Hyp-OEt (Syrup);(4R)-1-Boc-4-hydroxy-L-proline ethyl ester;(2S,4R)-N-Boc-trans-4-hydroxy-L-proline ethyl ester;1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

CBNumber:: CB3947104

Molecular Formula:: C12H21NO5

Molecular Weight:: 259.3

MDL Number:: MFCD09264314

MOL File:: 37813-30-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:48:15

Product description	Number	Pack Size	Price
Boc-Hyp-OEt ≥97%	CS-0045010	1g	$7
Boc-Hyp-OEt ≥97%	CS-0045010	5g	$9
Boc-Hyp-OEt ≥97%	CS-0045010	10g	$15
Boc-Hyp-OEt ≥97%	CS-0045010	25g	$26
Boc-Hyp-OEt ≥97%	CS-0045010	100g	$89
More product size

Request For Quotation

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Properties

Boiling point	350.2±42.0 °C(Predicted)
Density	1.189±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	14.30±0.40(Predicted)
form	Viscous Liquid
color	Colorless to light yellow
optical activity	Consistent with structure

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester price More Price(50)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0045010	Boc-Hyp-OEt ≥97%	37813-30-2	1g	$7	2026-06-04	Buy
ChemScene	CS-0045010	Boc-Hyp-OEt ≥97%	37813-30-2	5g	$9	2026-06-04	Buy
ChemScene	CS-0045010	Boc-Hyp-OEt ≥97%	37813-30-2	10g	$15	2026-06-04	Buy
ChemScene	CS-0045010	Boc-Hyp-OEt ≥97%	37813-30-2	25g	$26	2026-06-04	Buy
ChemScene	CS-0045010	Boc-Hyp-OEt ≥97%	37813-30-2	100g	$89	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0045010	1g	$7	Buy
CS-0045010	5g	$9	Buy
CS-0045010	10g	$15	Buy
CS-0045010	25g	$26	Buy
CS-0045010	100g	$89	Buy

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Chemical Properties,Uses,Production

Uses

Boc-Hyp-OEt is a proline derivative[1].

Synthesis

24424-99-5

33996-30-4

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

37813-30-2

Step 2: Ethyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride (146.2 g, 0.747 mol) was dissolved in a solvent mixture of dichloromethane (1,600 mL) and ethanol (100 mL) and cooled to 0°C. Triethylamine (113.4 g, 1.12 mol, 156.2 mL) was added to this solution with stirring. Subsequently, di-tert-butyl dicarbonate (195.6 g, 0.90 mol) was added in batches. The reaction mixture was stirred at 0 °C for 15 minutes, then brought to room temperature and continued stirring for 16 hours. Upon completion of the reaction, the mixture was concentrated to about 800 mL and washed with water. The organic layer was dried with magnesium sulfate, filtered and concentrated. Purification by silica gel column chromatography (eluent: 20% ethyl acetate-dichloromethane) afforded ethyl Boc-L-hydroxyproline (193.7 g, 100%) as a yellow oil. Mass spectrum (M + Na): m/e 282. 1H-NMR (CDCl3) δ 1.30 (t, 3H), 1.45 (s, 9H), 1.75 (m, 1H), 2.10 (m, 1H), 2.30 (m, 1H), 3.45 and 3.55 (d, 1H, two rotary isomers), 3.65 (dd, 1H), 4.25 (m, 2H ), 4.40 and 4.45 (t, 1H, two rotary isomers), 4.55 (broad s, 1H).

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Preparation Products And Raw materials

Raw materials

Di-tert-butyl dicarbonate Boc-Hyp-OH Iodoethane H-HYP-OET HCL L-Proline, 4-hydroxy-, ethyl ester, (4R)- (9CI)

Ethanol Triethylamine Dichloromethane

1of2

Preparation Products

(2S,4R)-1-BOC-4-AMINO-PYRROLIDINE-2-CARBOXYLIC ACID

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Suppliers

Global( 94)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16512	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	21169	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15082	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9539	58
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	dominicguo@gk-bio.com	CHINA	9414	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
ATK CHEMICAL COMPANY LIMITED	60
GenicBio Limited	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Dideu Industries Group Limited	58
AFINE CHEMICALS LIMITED	58
Finetech Industry Limited	58
Baoji Guokang Healthchem co.,ltd	58
Nextpeptide Inc	58

View Lastest Price from 1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-04-17	Boc-Hyp-Oet 37813-30-2	$2.00-6.00	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
	2020-02-05	1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester 37813-30-2	$3.00	1KG	98%	100KG	Career Henan Chemical Co

Boc-Hyp-Oet
37813-30-2
$2.00-6.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester
37813-30-2
$3.00
98%
Career Henan Chemical Co

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Spectrum

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester(37813-30-2)¹HNMR

37813-30-2(1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester )Related Search:

Boc-L-beta-Homoproline N-Boc-D-alaninol Boc-O-benzyl-L-tyrosine N-Boc-cis-4-Hydroxy-L-proline methyl ester Boc-Hyp-OH

N-Boc-trans-4-Hydroxy-L-proline methyl ester BOC-L-TRANSPRO(OTS)-OBN BOC-HYP-OTBU BOC-HYP-OBZL 1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

1of2

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester 1-Boc-4-Hydroxy-L-Proline Ethyl Ester (2S,4R)-1-BOC-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID ETHYL ESTER Boc-L-Hydroxy-Proline Ethyl Ester (2S,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-tert-butyl 2-ethyl ester 1-Boc-L-hydroxyproline ethyl ester (2S-trans)-4-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 2-ethyl ester 1-tert-Butoxycarbonyl-4R-hydroxy-L-proline ethyl ester (2S,4R)-1-tert-Butyl 2-ethyl 4-hydroxypyrrolidine-1,2-dicarboxylate 37813-30-2) (2S)-1-tert-butyl 2-ethyl 4-hydroxypyrrolidine-1,2-dicarboxylate (4R)-1-Boc-4-hydroxy-L-proline ethyl ester 1-tert-butyl 2-ethyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate (2S)-4-hydroxypyrrolidine-1,2-dicarboxylic acid O1-tert-butyl ester O2-ethyl ester Boc-L-Hyp-oet (Tert-Butoxy)Carbonyl Hyp-OEt (Syrup) (2S,4R)-1-BOC-4-HYDROXYPYRROLININE-2-CARBOXYLIC ACID ETHYL ESTER 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S,4R)- 1-(tert-butyl) 2-ethyl (2S)-4-hydroxypyrrolidine-1,2-dicarboxylate 1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester USP/EP/BP O1-tert-butyl O2-ethyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Ethyl (2S,4R)-1-Boc-4-Hydroxypyrrolidine-2-carboxylate (2S,4R)-N-Boc-trans-4-hydroxy-L-proline ethyl ester BOC-L-Proline Ethyl ester 37813-30-2

一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Properties

SAFETY

Risk and Safety Statements

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester price More Price(50)

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Chemical Properties,Uses,Production

Uses

Synthesis

References

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Suppliers

View Lastest Price from 1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester manufacturers

1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester Spectrum

37813-30-2(1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester )Related Search: