H-LEU-NH2
- CAS No.
- 687-51-4
- Chemical Name:
- H-LEU-NH2
- Synonyms
- L-LEUCINE AMIDE;(S)-2-Amino-4-methylpentanamide;Leu-NH2;H-LEU-NH2;L-Leu-NH2;leucinamide;LEUCINE-NH2;L-Leucine amide≥ 98% (HPLC);H-Leu-NH2;(S)-2-amino-4-methylvaleramide
- CBNumber:
- CB4104520
- Molecular Formula:
- C6H14N2O
- Molecular Weight:
- 130.19
- MDL Number:
- MFCD00238027
- MOL File:
- 687-51-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| H-Leu-NH2 AldrichCPR | CDS003478 | 250 mg | $77.9 |
| L-Leucine amide Asreported | 281454 | 5g | $363 |
| L-Leucine amide Asreported | 281454 | 10g | $503 |
| L-Leucine amide Asreported | 281454 | 25g | $834 |
| L-Leucine amide Asreported | 281454 | 50g | $1171 |
| More product size | |||
| Melting point | 84-85 °C(Solv: benzene (71-43-2); ethanol (64-17-5)(10:1)) |
|---|---|
| Boiling point | 250.9±23.0 °C(Predicted) |
| Density | 0.980±0.06 g/cm3(Predicted) |
| storage temp. | -15°C |
| form | solid |
| pka | 16.08±0.50(Predicted) |
| InChI | InChI=1S/C6H14N2O/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H2,8,9)/t5-/m0/s1 |
| InChIKey | FORGMRSGVSYZQR-YFKPBYRVSA-N |
| SMILES | C(N)(=O)[C@@H](N)CC(C)C |
| FDA UNII | RP28A6538M |
| EPA Substance Registry System | Pentanamide, 2-amino-4-methyl-, (2S)- (687-51-4) |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | WGK 3 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
H-LEU-NH2 price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS003478 | H-Leu-NH2 AldrichCPR | 687-51-4 | 250 mg | $77.9 | 2026-04-30 | Buy |
| Usbiological | 281454 | L-Leucine amide Asreported | 687-51-4 | 5g | $363 | 2026-06-03 | Buy |
| Usbiological | 281454 | L-Leucine amide Asreported | 687-51-4 | 10g | $503 | 2026-06-03 | Buy |
| Usbiological | 281454 | L-Leucine amide Asreported | 687-51-4 | 25g | $834 | 2026-06-03 | Buy |
| Usbiological | 281454 | L-Leucine amide Asreported | 687-51-4 | 50g | $1171 | 2026-06-03 | Buy |
H-LEU-NH2 Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Definition
ChEBI: An amino acid amide that is L-leucine in which the carboxy OH group is replaced by NH2.
Synthesis
2666-93-5
687-51-4
The general procedure for the synthesis of (S)-2-amino-4-methylpentanamide from L-leucine methyl ester was as follows: to a 250 mL 24/40 interface single neck round bottom flask fitted with a stirrer was added a 10 mL methanol solution of 8.1 g (0.056 mol) of L-leucine methyl ester under nitrogen protection. Subsequently, 40 mL of a 28-30% solution of ammonia was added slowly and dropwise over about 20 minutes. The reaction was stirred continuously under nitrogen atmosphere for 72 hours. Upon completion of the reaction, the solution was concentrated under vacuum at a pressure of 5-10 mmHg using a rotary evaporator (Model: 13uchi Rotovapor R-124, Manufacturer: I3UCHI Seikagaku Corp., Switzerland). The concentrated residue was dissolved in 250 mL of water and extracted with dichloromethane (5 × 500 mL). The organic layers were combined into a 4 L conical flask and dried by adding anhydrous sodium sulfate. After filtration to remove the desiccant, the organic phase was again concentrated using a rotary evaporator at a pressure of 5-10 mmHg, resulting in 5 g of the white solid product (S)-2-amino-4-methylpentanamide.
References
[1] Patent: US2017/57911, 2017, A1. Location in patent: Paragraph 0060; 0127; 0129
H-LEU-NH2 Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3970 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Wuhan Fortuna Chemical Co.,Ltd | +86-2759207851; +8618007136271 | hk@fortunachem.com | China | 6006 | 58 |
| Shanghai Hanhong Scientific Co., Ltd. | +undefined17612118332 | Lucky@hanhonggroup.com | China | 5844 | 58 |
| Henan Zhongfan Industry Limited | +86-18906033525 +86-18906033525; | yiyunchem@163.com | China | 2845 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10002 | 58 |
View Lastest Price from H-LEU-NH2 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-02-02 | L-Leucinamide
687-51-4
|
$1.00-10.00 | 98% | 200TONS | Shaanxi Dideu Medichem Co. Ltd |
-
- L-Leucinamide
687-51-4
- $1.00-10.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
