Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI)
- CAS No.
- 87674-21-3
- Chemical Name:
- Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI)
- Synonyms
- 4-Acetyl-3-fluoropyridine;3-Fluoro-4-acetylpyridine;1-(3-Fluoro-4-pyridinyl)ethanone;1-(3-fluoropyridin-4-yl)ethan-1-one;Ethanone, 1-(3-fluoro-4-pyridinyl)-;Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI);Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI) ISO 9001：2015 REACH
- CBNumber:
- CB41052860
- Molecular Formula:
- C7H6FNO
- Molecular Weight:
- 139.13
- MDL Number:
- MFCD07375077
- MOL File:
- 87674-21-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-(3-Fluoropyridin-4-yl)ethanone 98% | PC201340 | 100mg | $21 |
| 1-(3-Fluoropyridin-4-yl)ethanone 98% | PC201340 | 250mg | $24 |
| 1-(3-Fluoropyridin-4-yl)ethanone 98% | PC201340 | 1g | $55 |
| 1-(3-Fluoropyridin-4-yl)ethanone 98% | PC201340 | 5g | $268 |
| 1-(3-Fluoropyridin-4-yl)ethanone 98% | PC201340 | 25g | $1231 |
| More product size | |||
| Boiling point | 199℃ |
|---|---|
| Density | 1.175 |
| Flash point | 74℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 1.10±0.18(Predicted) |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C7H6FNO/c1-5(10)6-2-3-9-4-7(6)8/h2-4H,1H3 |
| InChIKey | PPULDLJGJZUOBS-UHFFFAOYSA-N |
| SMILES | C(=O)(C1C=CN=CC=1F)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| HS Code | 2933399990 |
Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI) price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC201340 | 1-(3-Fluoropyridin-4-yl)ethanone 98% | 87674-21-3 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC201340 | 1-(3-Fluoropyridin-4-yl)ethanone 98% | 87674-21-3 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | PC201340 | 1-(3-Fluoropyridin-4-yl)ethanone 98% | 87674-21-3 | 1g | $55 | 2026-06-04 | Buy |
| Apolloscientific | PC201340 | 1-(3-Fluoropyridin-4-yl)ethanone 98% | 87674-21-3 | 5g | $268 | 2026-06-04 | Buy |
| Apolloscientific | PC201340 | 1-(3-Fluoropyridin-4-yl)ethanone 98% | 87674-21-3 | 25g | $1231 | 2026-06-04 | Buy |
Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI) Chemical Properties,Uses,Production
Synthesis
1187669-49-3
75-16-1
87674-21-3
Step 2: Synthesis of 1-(3-fluoropyridin-4-yl)ethanone To a stirred solution of 3-fluoro-N-methoxy-N-methylpyridine-4-carboxamide (1.2 g, 6.5 mmol) in tetrahydrofuran (THF) (15 mL) was slowly added methylmagnesium bromide (2M solution in THF, 16 mL, 32 mmol) at 0 °C. After addition, the reaction mixture was brought to room temperature and stirring was continued for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated ammonium chloride (NH4Cl) solution and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, washed sequentially with water and saturated saline, dried over anhydrous sodium sulfate (Na2SO4), and concentrated under reduced pressure to afford 0.650 g (92% yield) of the target product 1-(3-fluoropyridin-4-yl)ethanone as a colorless oil. Mass spectrum (MS): 140.1 [M+H]+.
References
[1] Patent: US2017/291894, 2017, A1. Location in patent: Paragraph 0486-0488
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 2, p. 787 - 797
[3] Patent: WO2009/114552, 2009, A1. Location in patent: Page/Page column 167
Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23506 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9984 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9976 | 58 |
View Lastest Price from Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-06-25 | Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI)
87674-21-3
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-
- Ethanone, 1-(3-fluoro-4-pyridinyl)- (9CI)
87674-21-3
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
